2017 American Transplant Congress
Willingness of End-Stage Renal Disease Patients (ESRD) without Hepatitis C (HCV) to Accept a HCV+ Kidney.
1UPENN, Philadelphia, PA; 2Yale, New Haven, CT
Background: New HCV drugs could reduce the risks of donor-derived HCV infection. However, it is unknown if HCV-negative (HCV-) ESRD patients would accept an HCV+…2017 American Transplant Congress
Evaluating T Cell Repopulation Post Alemtuzumab Induction with a Belatacept-Based Regimen.
Department of Surgery, Duke University, Durham, NC
We reported that alemtuzumab induction followed by belatacept-sirolimus based immunosuppression effectively prevents costimulation blockade resistant rejection (CoBRR). This study investigates the phenotypic characteristics of repopulating…2017 American Transplant Congress
Immune Monitoring-Guided Treatment of a Pediatric Patient with Sequential GvHD, Acute Rejection and CMV Infection Following Lung Transplantation.
Background: A 17 year old patient with cystic fibrosis (HLA-A11+, CMV-) underwent bilateral sequential lung transplantation (donor: HLA-A32+, CMV+). Immunosuppression (IS) consisted of Tacrolimus, MMF…2017 American Transplant Congress
The Treg/Th17 Axis: A Dynamic Balance Regulated by Stromal Laminins.
University of Maryland, Baltimore
Background: Our recent work demonstrated that laminins α4β1γ1 and α5β1γ1, components of the lymph node (LN) stroma, are differentially regulated. Tolerance is associated with relatively…2017 American Transplant Congress
Donor Leukocytes Are Eliminated by the Host's Immune System Shortly After Skin Transplantation in Mice.
We have recently reported the lack of donor passenger leukocytes in the recipient's lymphoid organs of mice recipient of a skin allograft. On the other…2017 American Transplant Congress
Prospective Monitoring of De Novo Donor-Specific Antibodies: Incidence, Clinical Outcomes and Dynamic Changes Over 5 Years After Kidney Transplantation.
Montefiore Medical Center Transplant Center, Albert Einstein College of Medicine, Bronx
Background: We aimed to investigate the incidence and dynamic changes of de novo donor-specific-antibodies (dnDSA) after kidney transplantation and clinical outcomes.Methods: This is a prospective…2017 American Transplant Congress
Risk of Kidney Rejection Following Simultaneous Liver Kidney Transplantation.
Introduction: Simultaneous liver kidney transplant (SLK) recipients may be at risk of antibody-mediated kidney rejection (AMR) if the pre-transplant crossmatch is positive (+CXM). Accordingly, in…2017 American Transplant Congress
Factors in Association with Sepsis Differ Between Simultaneous Pancreas/Kidney and Single Kidney Transplant Recipients.
As immunosuppressive therapy and allograft survival have improved in simultaneous pancreas/kidney transplant recipients (SPKTRs), the increased incidence of infection has become a major hurdle of…2017 American Transplant Congress
Myeloid HO-1 Regulates M2 Macrophage Activation in Liver Ischemia-Reperfusion Injury (IRI).
Background/Aim: Although anti-inflammatory macrophage differentiation (M2) from pro-inflammatory (M1) phenotype is critical for heme oxygenase-1 (HO-1) cytoprotection, the role of cell type-specific HO-1 induction remains…2017 American Transplant Congress
Prolonged Liver Ischemia Triggers Necrotic Depletion of TIM4+ Kupffer Cells to Facilitate Tissue Inflammatory Immune Activation in Liver Ischemia-Reperfusion Injury.
Although mechanisms of immune activation against liver ischemia-reperfusion injury (IRI) have been studied extensively, questions regarding liver resident Kupffer cells vs. infiltrating macrophages (iM[Oslash]s) remain…
- 1
- 2
- 3
- …
- 181
- Next Page »