2017 American Transplant Congress
The miRNome of EBV+ PTLD is Distinct from EBV+ Infectious Mononucleosis.
Post-transplant lymphoproliferative disorder (PTLD) is a potentially fatal complication of organ transplantation commonly associated with Epstein Barr virus (EBV) infection. More than 90% of the…2017 American Transplant Congress
Maribavir for Treatment of Cytomegalovirus Infections Resistant or Refractory to Ganciclovir or Foscarnet in Solid Organ Transplant Recipients: A Phase 2 Study.
Study NCT01611974 assessed safety, tolerability, and antiviral activity of maribavir (MBV) for treatment of resistant or refractory (R/R) CMV infections among transplant recipients. Those aged…2017 American Transplant Congress
Regulatory T Cells Inhibit Plasmablast Formation and IgG Production by Tempering T Follicular Helper Cell Function.
Thomas E. Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA
Background: Donor-specific antibodies (DSA) are an important biomarker for acute rejection, transplant glomerulopathy and late allograft failure in kidney transplantation. Few studies have characterized the…2017 American Transplant Congress
HLA Donor-Specific Antibody (DSA) Negative Antibody-Mediated Rejection (AMR): Incidence, Treatment and Outcomes.
Background: Banff 2013 criteria for the diagnosis of antibody-meditated rejection (AMR) in kidney transplants require the presence of donor-specific antibody (DSA). Clinical significance of histological…2017 American Transplant Congress
CXCL12 Modulation of Localized Immune Responses to Subcutaneous Islet Macrocapsulation.
Infectious Disease, Massachusetts General Hospital, Boston, MA
Purpose:To determine the impact of CXCL12 on vascularization and immune response to xeno islets transplanted into TheraCyte macroencapsulation device in diabetic C57BL/6 mice.Materials and Methods:Three…2017 American Transplant Congress
Factors Affecting Desensitization Outcome.
The purpose of this study was to identify factors that affect the outcome of desensitization. We reviewed antibody and HLA mismatch data from 114 patients…2017 American Transplant Congress
Re-Evaluation of Imaging Studies in Patients with Hepatocellular Carcinoma at a Transplant Center Impacts Patient Care.
Organ Transplant, Scripps Clinic, La Jolla, CA
Introduction: The United Network for Organ Sharing (UNOS) requires confirmation of HCC based on imaging to be made at a transplant center. This places a…2017 American Transplant Congress
OPO-Wide Waitlist Size and Deceased Donor Kidney Transplant Rate.
1JHU, Baltimore, MD; 2USNA, Annapolis, MD
Substantial geographic disparity exists in access to deceased donor kidney transplantation (DDKT); mechanisms for the disparity are not fully understood. The relationship between OPO-wide waitlist…2017 American Transplant Congress
Outcomes of Deceased Donor Kidney Transplantation in Elderly Recipients Aged 70 Years and Older.
Introduction: The number of patients aged 70 years and older receiving renal replacement therapy is increasing. There is uncertainty regarding whether listing for deceased donor…2017 American Transplant Congress
Human Transitional B Cell Cytokine Profile Predicts Renal Allograft Rejection and Clinical Course.
In Kidney Transplant Recipients (KTRs), non-invasive predictive biomarkers that allow early intervention are limited. Here we report findings from a prospective longitudinal study using B…
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