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American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Epitope Load Is Predictive of De Novo Donor Specific Antibodies Occurrence in Renal Transplant Recipients After Conversion from Cyclosporine to Everolimus.

    R. Snanoudj,1 C. Suberbielle,2 N. Kamar,3 E. Cassuto,4 S. Caillard,5 J.-L. Taupin,2 D. Anglicheau,1 C. Legendre,1 A. Hertig,6 E. Rondeau.6

    1Necker Hospital, Paris, France; 2Saint-Louis Hospital, Paris, France; 3Rangueil Hospital, Toulouse, France; 4Pasteur Hospital, Nice, France; 5CHRU, Strasbourg, France; 6Tenon Hospital, Paris, France.

    IntroductionThe degree of HLA compatibility between donor and recipient is an important risk factor of developing de novo DSA, but misjudged by the number of…
  • 2016 American Transplant Congress

    Predonation Prescription Narcotic Use: A Novel Risk Factor for Readmission After Living Donor Nephrectomy.

    K. Lentine,1,7 D. Segev,2,1 D. Axelrod,3 N. Lam,4 A. Garg,5 G. Hess,6 B. Kasiske,1 D. Brennan,8 H. Randall,7 M. Schnitzler.7,1

    1Scientific Registry of Transplant Recipients, Minneapolis; 2Johns Hopkins, Baltimore; 3Dartmouth, Hanover; 4Univ Alberta, Alberta, Canada; 5Western Univ, London, Canada; 6Symphony Health, Pittsburgh; 7Saint Louis Univ, St. Louis.

    Implications of narcotic use in living kidney donor (LKD) candidates for key outcomes, including readmission rates after nephrectomy, are unknown.We integrated 1) national Scientific Registry…
  • 2016 American Transplant Congress

    Mining the Human Proteome for Monitoring Renal Transplant Injury.

    T. Sigdel,1 Y. Gao,2 J. He,2 A. Wang,1 C. Nicora,2 D. Smith,2 W. Qian,2 D. Camp,2 M. Sarwal.1

    1Surgery, University of California-San Francisco, San Francisco; 2Pacific Northwest National Laboratory, Richland.

    The human urinary proteome reflects systemic and inherent renal injury perturbations and can be harnessed to define biomarkers for different kidney transplant injury states. Through…
  • 2016 American Transplant Congress

    Analysis of Broken Chains in Kidney Paired Donation During an 8 Year Period within the National Kidney Registry.

    N. Cowan,1 J. Sinacore,2 H. Gritsch,1 J. Veale.1

    1Department of Urology, University of California - Los Angeles Medical Center, Los Angeles, CA; 2National Kidney Registry, Babylon, NY.

    Purpose: Chain transplantation in kidney paired donation (KPD) offers the ability to facilitate multiple kidney transplants between incompatible pairs using a non-directed donor (NDD) to…
  • 2016 American Transplant Congress

    Hospitalization and Living Donor Kidney Transplantation Among Waitlisted End Stage Renal Disease Patients in the US.

    K. Newman,1,2 A. Adams,2 S. Pastan,2 R. Lynch,2 R. Zhang,1 R. Patzer.1,2

    1Emory University Rollins School of Public Health, Atlanta, GA; 2Emory University School of Medicine, Atlanta, GA.

    Background: For End Stage Renal Disease Patients (ESRD) waitlisted for a deceased donor kidney, living donor kidney transplantation (LDKT) could allow for earlier transplantation and…
  • 2016 American Transplant Congress

    Racial Differences Amongst Infants Undergoing Intestine Transplants.

    K. Khan, C. Desai, S. Kaufman, R. Girlanda, J. Hawksworth, A. Kroemer, T. Fishbein, C. Matsumoto.

    Transplant Institute, MedStar Geogetown University Hospital, Washington, DC.

    BackgroundIt is known that the demographics of the United States are changing because of immigration and increased birth rates in non-white populations. Here we examine…
  • 2016 American Transplant Congress

    Late Renal Xenograft Failure Is Antibody-Mediated: Description of the Longest-Reported Survival in Pig-to-Primate Renal Xenotransplantation.

    L. Higginbotham,1 S. Kim,1 D. Mathews,1 A. Stephenson,1 C. Breeden,1 C. Larsen,1 M. Ford,1 K. Newell,1 A. Tector,2 A. Adams.1

    1Emory Transplant Center, Emory University Hospital, Atlanta, GA; 2Indiana University School of Medicine, Indianapolis, IN.

    Introduction. Xenotransplantation has the potential to alleviate the organ supply shortage, yet pig-to-primate renal xenotransplant has met limited success due to natural preformed anti-pig antibody.…
  • 2016 American Transplant Congress

    Autologous BK-Specific T-Cell Lines in Kidney Transplant Recipients.

    C. Lamarche,1,2,3 O. Julie,1,3 C. Carli,1,3 J.-S. Delisle.1,2,3

    1Centre de Recherche de l'Hôpital Maisonneuve-Rosemont, Montreal, QC, Canada; 2Canadian National Transplant Research Program (CNTRP), Edmonton, Canada; 3ThéCell Network, Quebec, Canada.

    Background: More than 75% of the population has been exposed to BK polyomavirus and carries latent virus in the uroepithelium. Immunocompetent hosts are asymptomatic but…
  • 2016 American Transplant Congress

    Calcineurin Inhibitors Promote Metastasis in Post-Transplant Colorectal Cancer Through Cancer Related- Exosomes Released from Cancer Cells in TGF Beta Independent Epitheilal to Mesenquimal Transition.

    V. Tubita,1 J. Segui-Barber,4 M.-J. Ramírez-Bajo,1 D. Moya-Rull,1 P. Piselli,3 D. Verdirosi,3 F. Oppenheimer,1,2,5 D. Serraino,6 H. Del Portillo,4,7 F. Diekmann,1,2,5 J. Campistol,1,2,5 I. Revuelta.1,2,5

    1Experimental Laboratory of Nephrology and Kidney Transplant, IDIBAPS, Barcelona, Spain; 2Department of Nephrology and Kidney Transplant, Hospital Clínic, Barcelona, Spain; 3Dipartamento di Epidemiologia e Ricerca Pre-Clinica, INMI “L. Spallanzani” IRCCC, Rome, Italy; 4ISGlobal, CRESIB, Hospital Clínic, Universitat de Barcelona, Barcelona, Spain; 5National Network for Kidney Research (REDinREN), Carlos III Royal Institute, Ministry of Health, Madrid, Spain; 6IRCCS Centro di Riferimento Oncologico, Aviano, Italy; 7Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain.

    Introduction: Cancer is one of the major causes of death in kidney transplantation. Despite more mortality in colon cancer (CRC), similar incidence than general population…
  • 2016 American Transplant Congress

    Pancreatic Allograft Failure in Latino Recipients: Diabetes Mellitus Type 2 Conversion?

    H. Fernandez, G. McKenna, N. Onaca, R. Ruiz.

    Baylor University Medical Center, Dallas, TX.

    Introduction:Pancreas transplantation is the definitive treatment for diabetes mellitus (DM). The advantages of simultaneous kidney pancreas transplant in Latinos have been demonstrated previously, but there…
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