Am J Transplant, Volume 16, Suppl 3 Archives - Page 93 of 180 - ATC Abstracts

2016 American Transplant Congress
Recombinant TSGL-Ig Protects Liver Endothelial Cells Against Prolonged Cold Preservation Injury in Mouse Liver Transplantation.
C. Zhang,^1,2 H. Ji,¹ Y. Liu,^1,2 Y. Zhang,^1,2 X.-D. Shen,¹ F. Gao,¹ R. Busuttil, G. Shaw, J. Kupiec-Weglinski.
¹Dumont-UCLA Transplant Center, Division of Liver and Pancreas Transplantation, Department of Surgery, David Geffen School of Medicine at University of California-Los Angeles, Los Angeles, CA; ²Department of Surgery, Division of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
Background: Liver endothelial cells (LEC) suffer from ROS-mediated stress in the pathogenesis of liver ischemia-reperfusion injury (IRI). We used a novel recombinant form of soluble…
2016 American Transplant Congress
Distinctive Roles of Gsk3 Inhibitory Phosphorylation in Liver Inflammatory Immune Response and Hepatocellular Injury Against Ischemia Reperfusion.
H. Zhou,^1,2 J. Zhu,¹ S. Yue,¹ R. Busuttil,¹ J. Kupiec-weglinski,¹ L. Lu,² Y. Zhai.¹
¹Surgery, David Geffen School of Medicine-UCLA, Los Angeles, CA; ²Liver Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, China.
Background & AimsGlycogen synthase kinase 3 (Gsk3) a and b are ubiquitously expressed, constitutively active serine/threonine kinases, which play complex roles in cell activation, proliferation…
2016 American Transplant Congress
Attenuation of Warm Hepatic Ischemia-Reperfusion Injury by Bruton's Tyrosine Kinase Inhibition.
A. Zarrinpar,¹ T. Palumbo,¹ K. Nakamura,¹ C. Lassman,² R. Busuttil,¹ J. Kupiec-Weglinski.¹
¹Surgery, Dumont-UCLA Translant Center, Los Angeles, CA; ²Pathology, UCLA, Los Angeles, CA.
Bruton's tyrosine kinase (Btk) is a central player in multiple signaling pathways in lymphoid and myeloid cells, including neutrophils. Neutrophils are crucial effectors in the…
2016 American Transplant Congress
Measured Glomerular Filtration Rate of the Remaining Kidney Divided by Its Volume Prior to Donation Is a Predictor of the Long-Term Gain of Function in Living Kidney Donors.
M. Courbebaisse,¹ F. Gaillard,² A. Le Nestour,⁴ J.-M. Correas,³ H. Slimani-Thevenet,⁵ C. Leon,² D. Eladari,¹ M.-O. Timsit,⁶ P. Otal,⁷ G. Friedlander,¹ P. Houillier,¹ N. Kamar,⁸ C. Legendre.²
¹AP-HP, Georges Pompidou European Hospital, Physiology department, Paris Descartes University, and INSERM, Unit 1151, Paris, France; ²AP-HP, Hôpital Necker-Enfants Malades, Renal Transplantation Department, Paris Descartes University, Paris, France; ³AP-HP, Hôpital Necker-Enfants Malades, Radiology Department, and Paris Descartes University, Paris, France; ⁴University of Otago, Biostastistic department, Otago, New Zealand; ⁵AP-HP, Georges Pompidou European Hospital , Nuclear Medicine department, Paris Descartes University, and INSERM, Unit 1151, Paris, France; ⁶AP-HP, Georges Pompidou European Hospital , Nuclear Medicine department, Paris Descartes University, and INSERM, Unit 1151, Paris, France; ⁷Toulouse University Hospital, CHU Rangueil, Department of Radiology, Paul Sabatier University, Toulouse, France; ⁸Toulouse University Hospital, CHU Rangueil, Department of Nephrology and Organ Transplantation, Paul Sabatier University, INSERM U1043, IFR–BMT, CHU Purpan, Toulouse, France.
Predictors of long-term renal function in living kidney donors are a matter of debate. To describe the predictors of remaining kidney functional gain, we conducted…
2016 American Transplant Congress
End Stage Renal Disease (ESRD) Patients' Willingness to Accept Risks to Living Kidney Donors.
J. Gannon,¹ C. Thiessen,¹ K. Yu,¹ L. Skrip,¹ P. Reese,² E. Gordon,³ S. Kulkarni.¹
¹Yale University, New Haven; ²University of Pennsylvania, Philadelphia; ³Northwestern University, Chicago.
Background: While many potential living kidney donors (LKDs) are willing to accept high levels of ESRD risk, receipt of a living donor kidney is also…
2016 American Transplant Congress
Influence of Cold Ischemia Time in Kidney Transplants from Small Pediatric Donors.
L. Kayler,¹ M. Lubetzky,² P. Friedman.³
¹Erie County Medical Center, Buffalo; ²Montefiore Medical Center, Bronx; ³Montefiore Medical Center, Bronx.
Clinicians may be reluctant to transplant small pediatric kidneys that also have prolonged cold ischemia time (CIT) for fear of an additional deleterious effect since…
2016 American Transplant Congress
Deceased Donor ABO-Incompatible Kidney Transplantation Has the Potential to Reduce Blood Group Disparity.
M. Manook,¹ L. Bradbury,² D. Osei-Bordom,¹ B. Sandhu,¹ T. Maggs,¹ O. Shaw,¹ N. Kessaris,¹ S. Shah,³ A. Dorling, N. Mamode.¹
¹Guy's & St Thomas' Hospital, London, United Kingdom; ²NHS Blood & Transplant, Bristol, United Kingdom; ³King's College Hospital, London, United Kingdom.
Introduction: Patients with blood group O or B wait significantly longer for a kidney transplant than other groups. Blood group incompatible transplantation is widely accepted…
2016 American Transplant Congress
Predicting and Reducing 30-Day Readmission After Liver Transplant (OLT).
K. Eid, M. Elshamy, L. Louwers, B. Eghtesad, C. Quintini, K. Snyder, F. Aucejo, K. Hashimoto, M. Fujiki, C. Miller, D. Kelly.
Transplant Surgery, Cleveland Clinic Foundation, Cleveland, OH.
Background:Reducing early readmissions is a challenge. This study aimed to identify predictors of 30-day readmissions and interventions to minimize readmissions.Methods: Records of 523 adult OLT…
2016 American Transplant Congress
The Use of Thromboelastography (TEG) in Preoperative Pediatric Liver Transplantation to Predict Postoperative Thrombotic Complications.
K. Curiel,¹ B. Wicklund,² K. Gonzalez,¹ W. Andrews,¹ V. Fioravanti,¹ R. Hendrickson.¹
¹Department of Pediatric Surgery, Children's Mercy Hospital, Kansas City, MO; ²Department of Hematology, Children's Mercy Hospital, Kansas City, MO.
Introduction: Little data exists in the use of thromboelastography (TEG) in pediatric liver transplantation. In 2011 we implemented pre-transplant TEGs for patients listed for liver…
2016 American Transplant Congress
Extraperitoneal Placement of the Kidney Prevents Graft Vascular Kinking or Rotation in Simultaneous Pancreas-Kidney Transplant (SPK).
M. Maraschio, A. Alcaraz, E. Giordano Segade.
Pancreas-Kidney Transplant Program, Hospital Privado Universitario de Córdoba, Cordoba, Argentina.
BACKGROUND: The preferred technique for kidney placement in SPK is intraperitoneal through a midline incision, as it is easy and fast to be performed. However,…