Am J Transplant, Volume 16, Suppl 3 Archives - Page 90 of 180 - ATC Abstracts

2016 American Transplant Congress
Relationship Between Dialisys Duration and Prevalence of Cardiovascular Diseases in Kidney Transplantation Recipients.
K. Unagami,¹ M. Okumi,² T. Hirai,² Y. Okabe,³ K. Masutani,⁴ T. Shimizu,² K. Omoto,² M. Inui,² H. Ishida,² T. Kitazono,⁴ K. Nitta,¹ K. Tanabe,² The Japan Academic Consortium of Kidney Transplantation (JACK).
¹Nephrology, Tokyo Women's Medical University, Tokyo, Japan; ²Urology, Tokyo Women's Medical University, Tokyo, Japan; ³Surgery, Kyushu University, Fukuoka, Japan; ⁴Medicine and Clinical Science, Kyushu University, Fukuoka, Japan.
Background: Among kidney transplantation (KTx) recipients, the prevalence of Cardiovascular disease (CVD) is high. However, to our knowledge, the relationship between the prevalence of CVD…
2016 American Transplant Congress
Quantiferon-CMV Test, CMV-Specific ELISPOT and CMV-Dextramer Assays in Assessing the Risk of CMV Infection in Seropositive Kidney Transplant Recipients.
H. Lee,¹ K. Park,² J. Ryu,² J. Yu,³ B. Chung,³ C. Yang,³ E.-J. Oh.¹
¹Department of Laboratory Medicine, The Catholic University of Korea, Seoul, Korea; ²Department of Biomedical Science, Graduate School, The Catholic University of Korea, Seoul, Korea; ³Division of Nephrology, Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.
Human cytomegalovirus (CMV) infection is one of the primary opportunistic pathogens and is a leading cause of morbidity and mortality in kidney transplant recipients. Assessing…
2016 American Transplant Congress
Predictors of Post Transplant Lymphoprolipherative Disorder Among Adult Kidney Transplant Recipients.
M. Mohamed, S. Parajuli, B. Muth, A. Djamali, B. Astor.
Internal Medicine, University of Wisconsin School of Medicine, Madison, WI.
Objective: Identifying predictors of Post Transplant Lymphoprolipherative Disorder (PTLD); early (0 - 3 years) and late in kidney transplantation.Methodology: Single center longitudinal study among kidney…
2016 American Transplant Congress
C1q Donor Specific Antibody Associates with Post Transplant Biopsy Findings in Highly Sensitized Kidney Transplant Recipients.
S. Kuppachi,¹ D. Holanda,² S. Gallegos,³ E. Field.^3,4
¹Nephrology, University of Iowa Hospitals and Clinics, Iowa City, IA; ²Pathology, University of Iowa Hospitals and Clinics, Iowa City, IA; ³Iowa Regional Histocompatibility and Immunogenetics Laboratory, Veteran Affairs Medical Center, Iowa City, IA; ⁴Immunology, University of Iowa Hospitals and Clinics, Iowa City, IA.
We performed monitoring of conventional donor specific antibodies (DSA) and C1q binding DSA (C1q DSA) to correlate levels with pathology findings in protocol kidney biopsies…
2016 American Transplant Congress
The Effect of Tocilizmab Treatment (TCZ-Rx) on Total IgG and Anti-CMV-IgG Levels in HLA-Sensitized (HS) Kidney Transplant Patients.
B.-H. Shin, S. Ge, J. Choi, J. Kahwaji, A. Vo, A. Petrosyan, S. Jordan, M. Toyoda.
Transplant Immunology Lab, Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA.
Background: TCZ has anti-B cell and anti-inflammatory properties. We have reported its successful use for pre-transplant (Tx) desensitization (DES) and treatment of ABMR. We also…
2016 American Transplant Congress
Inflammatory Conditions Switch the Effect of MSC on B Cells from Pro-Tolerogenic to Anti-Proliferative.
M. Franquesa,^1,2 F. Luk,¹ S. Korevaar,¹ L. Boon,³ F. Borras,² M. Betjes,¹ C. Baan,¹ M. Hoogduijn.¹
¹Transplantation and Nephrology Lab, Internal Medicine, Erasmus MC, Rotterdam, Netherlands; ²IVECAT, Nephrology Department, IGTP, Badalona, Spain; ³Bioceros, Utrecht, Netherlands.
The immunomodulatory capacity of mesenchymal stem cells (MSC) makes them a promising therapeutic tool in transplantation. MSC are recently gaining interest for their immunomodulatory effects…
2016 American Transplant Congress
IgM Treatment Successfully Prevents Type 1 Diabetes by Dysregulation of Pancreatic MicroRNAs with Immunomodulatory Roles.
P. Chhabra, R. Gehrau, V. Mas, D. Bower, D. Maluf, K. Brayman.
UVA, Charlottesville.
Type 1 Diabetes (T1D) is hallmarked by beta-cells destruction. We aimed to identify specific pancreatic microRNAs (miRNA) as potential biomarkers for T1D prediction and diagnosis,…
2016 American Transplant Congress
Chemokine Receptor CXCR4 Antagonist, a Novel Pathway to Prevent Chronic Allograft Nephropathy.
Y. Xu, Q. Zhang, X. Hu.
Department of Urology, Beijing Chaoyang Hospital, Beijing, China.
BackgroundChronic allograft nephropathy (CAN) remains a major problem for long term graft survival and different pathways participate in its development. CXC chemokine receptor 4 (CXCR4)…
2016 American Transplant Congress
Memory Regulatory T Cell: A Potential Actor in Immunological Operational Tolerance in Kidney-Transplant Patients via the ATP Degradation into Adenosine.
M. Durand,^1,2 F. Braza,¹ N. Degauque,¹ F. Dubois,² M. Chesneau,¹ P. Guérif,^1,3 M. Giral,^1,3 S. Brouard.¹
¹ITUN-INSERM U1064, Nantes, France; ²University of Nantes, Nantes, France; ³Biotherapy Clinical Investigation Center, Nantes, France.
Regulatory T cells (Tregs) are essential actors in the control of self-tolerance and exacerbated inflammation. In experimental transplantation Tregs are critical to achieve alloantigen tolerance…
2016 American Transplant Congress
Outcomes of Untreated Asymptomatic Bacteriuria in Renal Transplant Recipients: A Single-Center Experience.
W. Davis, R.-A. Lee, L. Daniels, S. Todd, K. True, P. Chong.
University of North Carolina Medical Center, Chapel Hill, NC.
Background. Renal transplant recipients (RTR) with asymptomatic bacteriuria (AB) are often treated with antibiotics. This could lead to complications related to antibiotic treatment including Clostridium…