ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Colonization and Risk of Bacteremia by Multi-Drug Resistant Organisms in Intestinal Transplant Recipients.

    J. Simkins,1 J. Camargo,1 M. Morris,1 R. Vianna,2 T. Beduschi,2 L. Abbo.1

    1Medicine/Infectious Diseases, University of Miami Miller School of Medicine, Miami, FL; 2Surgery, Miami Transplant Institute/University of Miami, Miami, FL.

    Background: This study is the first to evaluate colonization rates and subsequent bacteremia with multi-drug resistant organisms (MDRO) in intestinal transplant (ITx) recipients.Methods: Retrospective study…
  • 2016 American Transplant Congress

    When Living Donor Liver Allografts Fail: Exploring the Pitfalls of Retransplantation Using Deceased Donor Organs.

    T. Bittermann,1 A. Shaked,2 K. Lloyd,2 D. Goldberg.1

    1Gastroenterology and Hepatology, University of Pennsylvania, Philadelphia, PA; 2Transplant Surgery, University of Pennsylvania, Philadelphia, PA.

    Background: In the US, living donor liver transplantation (LDLT) is associated with increased long-term graft and patient survival compared to deceased donor liver transplantation (DDLT).…
  • 2016 American Transplant Congress

    Short UK Dialysis Does Not Significantly Impact on Live Donor Kidney Allograft Survival.

    A. Bentall,1,2 M. Jesky,1,2 R. Borrows,1,2 R. Johnson,3 S. Ball.1,2

    1Department of Nephrology, University Hospitals Birmingham, Birmingham, United Kingdom; 2School of Immunity and Infection, University of Birmingham, Birmingham, United Kingdom; 3NHSBT, Bristol, United Kingdom.

    Background. The survival advantage of pre-emptive transplantation (Pre-empTx) in live donor kidney transplantation (LDKTx) was reported by Meier-Kreische (Kidney International, 2000). Dialysis practices differ internationally…
  • 2016 American Transplant Congress

    Earlier Repletion of Lymphocytes After Alemtuzumab Induction Is Associated with a Lower Incidence of Infection Following Renal Transplantation.

    M. Willicombe, D. Goodall, A. McLean, D. Taube.

    Imperial College Renal and Transplant Centre, Hammersmith Hospital, London, United Kingdom.

    Introduction: Alemtuzumab has been increasingly used as an induction agent in renal transplantation, although the optimal dose is unknown. We have previously reported that alemtuzumab…
  • 2016 American Transplant Congress

    Twenty Years of Evolving Trends in Racial Disparities for Adult Kidney Transplant Recipients.

    D. Taber, M. Gebregziabher, K. Chavin, T. Srinivas, P. Baliga, L. Egede.

    Med Univ of South Carolina, Charleston, SC.

    Objective: To determine if baseline risks and post-transplant outcome disparities in African American (AA) kidney transplant recipients have evolved over time.Methods: Analysis of 20-years of…
  • 2016 American Transplant Congress

    Exosomes with Lung Associated Self-Antigens (Collagen V and K alpha 1 Tubulin): Role in Rejection Following Human Lung Transplantation.

    M. Gunasekaran,1,2 Z. Xu,1,2 D. Nayak,1,2 M. Sharma,1,2 R. Hachem,1 T. Mohanakumar.1,2

    1Surgery, Pathology & Immunology, & Medicine, Washington Univ Sch Med, St. Louis, MO; 2Norton Thoracic Institute - St. Joseph's Hospital, Phoenix, AZ.

    Immune response to HLA and non-HLA antigens play a significant role in the development of chronic and acute rejection (AR), bronchiolitis obliterans syndrome (BOS), following…
  • 2016 American Transplant Congress

    Subnormothermic Machine Perfusion (SNMP) Leads to Increased Bile Production and Secretion of Hydrophilic Bile Acids After Liver Transplantation When Compared to Cold Storage (CS).

    B. Banan, R. Lopez, Z. Khan, C. Hughes, G. Michalopoulos, P. Fontes.

    University of Pittsburgh, Pittsburgh.

    Background: Bile production during machine perfusion and after transplantation has been used as marker of liver allograft viability and function. This study aimed to assess…
  • 2016 American Transplant Congress

    A 5-Year Multicenter Evaluation of Seasonal Influenza Infection in Transplant Recipients.

    D. Kumar,1 E. Cordero,4 E. Blumberg,2 A. Limaye,5 M. Levi,7 L. Danziger-Isakov,9 J. Englund,8 S. Husain,1 F. Silveira,10 G. Reid,6 T. Sharma,3 A. Humar.1

    1UHN, Toronto, Canada; 2UPenn, Philadelphia; 3BCH, Boston; 4REIPI, Seville, Spain; 5UoWMC, Seattle; 6LUMC, Chicago; 7UCD, Denver; 8SCH, Seattle; 9CCHMC, Cincinnati; 10UPMC, Pittsburgh.

    Background:Seasonal influenza infection may cause significant morbidity and mortality in transplant patients. However, there are limited prospective data on clinical presentations and determinants of outcomes.…
  • 2016 American Transplant Congress

    Circulating Angiotensin II Receptor: Possible Marker for Antibody Mediated Tissue Injury?

    P. Kimball, F. McDougan, G. Gupta.

    Transplant Surgery, VCU Health, Richmond, VA.

    Background. Antibody mediated rejection is the leading cause of renal allograft failure. Membrane-bound angiotensin II receptor(AngII) in the renal allograft can be a target of…
  • 2016 American Transplant Congress

    Levels of VEGF-C, PLGF and Follistatin at 12 Months Post Transplantation Are Associated with Increased Risk for Long Term Progressive Renal Dysfunction.

    G. Dreyer,1 J. de Fijter,1 D. Briscoe,2 K. Daly,2 M. Reinders.1

    1Nephrology, LUMC, Leiden, Netherlands; 2Transplantation Research Center, Boston Children's Hospital, Boston, MA.

    *contributed equallyIntroduction Integrity of the microvasculature is critical for long term survival after solid organ transplantation. We hypothesize that biomarkers of endothelial injury and repair…
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