ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Urinary Virome in Human Kidney Transplants Reveals Multiple Virus Subtypes with Distinct Genome Polymorphisms.

    R. Ranjan,1 A. Rani,1 H. McGee,1 D. Brennan,2 P. Finn,1 D. Perkins.1,3

    1Medicine, University of Illinois, Chicago, IL; 2Division of Renal Diseases, Washington University School of Medicine, St. Louis, MO; 3Surgery, University of Illinois, Chicago, IL.

    Recent studies have established that human urine has its own unique microbiome, but little is known about the virome. The human virome is the collection…
  • 2016 American Transplant Congress

    Pregnancy in the Renal Transplant Recipient: Pregnancy Viability and Effects on Graft Function.

    A. Lima, M. Cristelli, C. Teixeira, I. Pietrobom, G. Basso, L. Viana, M. de Paula, C. C[acirc]ndido, H. Tedesco-Silva, J. Pestana.

    Nephrology, Hospital do Rim, São Paulo, Brazil.

    Background: Fertility in women is recovered few months after kidney transplantation. However, pregnancy viability and maternal complications remain uncertain. Methods: We studied data of patients…
  • 2016 American Transplant Congress

    Evaluation of Patient-Reported Nonadherence with Tacrolimus Level Variability in Renal Transplant Recipients.

    N. Parrish,1 T. Kaiser,2 A. McCann,1 J. Aladimi,2 J. Harris,3 A. Govil,2 B. Abu Jawdeh,2 G. Mogilishetty,2 R. Alloway,2 E. Woodle.2

    1Pharmacy Services, University of Cincinnati Medical Center, Cincinnati, OH; 2Medicine, University of Cincinnati, Cincinnati, OH; 3Transplant, University of Cincinnati Medical Center, Cincinnati, OH.

    Medication nonadherence (NA) continues to be a major cause of graft loss post-transplant. Several methods for prospective adherence monitoring have been described including patient interview…
  • 2016 American Transplant Congress

    An In-Situ Treatment of Donor Skin Induces MARCH1 and Decreases MHC II Expression on Donor Dendritic Cells, Promoting Skin Allograft Acceptance.

    T. Borges,1,2 F. Machado,1 C. Bonorino,1 L. Riella.2

    1School of Biosciences and Biomedical Research Institute, PUCRS, Porto Alegre, RS, Brazil; 2Schuster Family Transplantation Research Center, Renal Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

    Background: Skin transplants are the most immunogenic of all transplants and donor DCs play a crucial role in activating effector alloreactive T cells and initiating…
  • 2016 American Transplant Congress

    Primary Graft Failure following Cardiac Transplantation Is Associated with Elevated Pre-Transplant Levels of Pro-Inflammatory Factors.

    D. Chatterjee,1 K. Clerkin,1 K. Rogers,1 D. Mancini,1 Y. Naka,1 H. Takayama,2 K. Takeda,2 P. Colombo,2 G. Vlad,3 R. Vasilescu,3 B. Levin,4 M. Farr,1 S. Restaino,1 E. Zorn.1

    1Columbia University Medical Center, NY; 2Surgery, Columbia University Medical Center, NY; 3Pathology & Cell Biology, Columbia University Medical Center, NY; 4Biostatistics, Columbia University Medical Center, NY.

    Primary graft failure (PGF) is defined as severe ventricular dysfunction immediately following heart transplantation (HTx) requiring temporary mechanical circulatory support (MCS) such as VA ECMO…
  • 2016 American Transplant Congress

    Latest VCA Statistics in the U.S.

    W. Cherikh,1 H. McGehee,1 C. Wholley,1 L. Levin,2 S. McDiarmid.3

    1United Network for Organ Sharing, Richmond, VA; 2Hosp of the Univ of Pennsylvania, Philadelphia, PA; 3UCLA Medical Center, Los Angeles, CA.

    Background. On July 3, 2014, the Organ Procurement and Transplantation Network/United Network for Organ Sharing (OPTN/UNOS) was charged with the oversight of Vascularized Composite Allograft…
  • 2016 American Transplant Congress

    Examining the Risk for Post-Transplant Viral Infections and Lymphoproliferative Disorder (PTLD) in Kidney Transplant Patients (Pts) Receiving Calcineurin Inhibitor-Based Immunosuppression (CNI-IS) Compared to Belatacept (CTLA4Ig).

    B. Shin, J. Choi, J. Kahwaji, S. Ge, D. Thomas, A. Vo, O. Galera, R. Villicana, A. Peng, S. Jordan, M. Toyoda.

    Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA.

    Introduction: CTLA4Ig is a novel IS agent that acts through costimulatory blockade of T-cells and obviates the need for CNI. Despite benefits in improving renal…
  • 2016 American Transplant Congress

    Impact of the Kidney Allocation System with Deceased Donor Kidney Utilization at the DSA Level.

    W. Ally,2 C. Saunders,1 K. Brayman,2 A. Agarwal.2

    1Lifenet Health, Virginia Beach, VA; 2University of Virginia Health System, Charlottesville, VA.

    Background: In December 2014, UNOS implemented broad sweeping changes in the new Kidney Allocation System (KAS). Recent summary reports by UNOS suggest that on a…
  • 2016 American Transplant Congress

    25-Hydroxyvitamin D Insufficiency Is Associated with Higher Risk of BK Virus Re-Activation After Kidney Transplantation.

    N. Elfadawy,1 S. Flechner,2 E. Poggio,2 B. Stephany,2 R. Fatica,2 J. Schold,2 S. Mossad.2

    1Internal Medicine, Case Western Reserve University, Cleveland, OH; 2Cleveland Clinic, Cleveland, OH.

    BACKGROUND: The past decade has seen increased interest in vitamin D, as new data suggest that it plays a role in the immune system. The…
  • 2016 American Transplant Congress

    Utility in Treating Renal Failure in End-Stage Liver Disease with Simultaneous Liver-Kidney Transplantation.

    X. Cheng,1 M. Stedman,1 W. Kim,2 J. Tan.1

    1Division of Nephrology, Stanford University, Palo Alto, CA; 2Division of Gastroenterology and Hepatology, Stanford University, Palo Alto, CA.

    The number of simultaneous liver-kidney transplants (SLKT) for end-stage liver disease (ESLD) with renal failure is rising. The overall utility of kidneys used in this…
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