2016 American Transplant Congress
Molecular Profiles of Renal Allograft Rejection.
Internal Medicine/Renal Medicine, University of Illinois at Chicago, Chicago, Il.
Introduction: The gold standard for the diagnosis of allograft rejection is the Banff Classification, yet it shows substantial variability among pathologists. Using molecular signatures of…2016 American Transplant Congress
Deceased Donor Urine C5a Predicts Donor and Recipient Acute Kidney Injury.
Anti-complement therapies are currently being tested in human kidney transplantation to prevent DGF. In this large prospective, cohort study of 469 deceased organ donors, we…2016 American Transplant Congress
Survival Benefit of High-KDPI Kidneys Among Obese Transplant Candidates.
Obese patients have less access to kidney transplantation; use of high-KDPI kidneys could help expand access in this population, but the cumulative effect of obesity…2016 American Transplant Congress
VO2peak Outperforms Troponin T for Risk Prediction of Cardiovascular Disease and All-Cause Mortality in Patients with End Stage Renal Disease Being Evaluated for Kidney Transplant.
1Mayo Clinic, Arizona; 2Arizona State University, AZ.
Background: Cardiovascular disease (CVD) is a major health care concern in end-stage renal disease (ESRD). Peak oxygen uptake (VO2peak) is a strong predictor of CVD…2016 American Transplant Congress
Adding Anti-Inflammatory Agents During Normothermic Ex-Vivo Liver Perfusion Improves the Preservation of Pig Liver Grafts Before Transplantation.
Multi Organ Transplant Program, Toronto General Hospital, Toronto, Canada.
Introduction: Normothermic ex vivo liver perfusion (NEVLP) improves graft preservation by avoiding cold ischemic injury. We investigated if protective effects of NEVLP can be further…2016 American Transplant Congress
Interaction Between Kidney Tissue Proteome and Humoral Immunity in Antibody Mediated Rejection.
PURPOSE: Antibody-mediated rejection (AMR) is caused by antibodies against human leukocyte antigens (HLA) on graft endothelium, and non-HLA antibodies that target endothelial and epithelial proteins.…2016 American Transplant Congress
Resveratrol Effectively Suppress Th17 Associated Allo-Immune Responses by the Modulation of AMPK/mTOR Pathway.
The aim of this study is to investigate the effect of resveratrol on Th17 allo-immune responses under tacrolimus (Tac)-based immune suppression. First, we investigated the…2016 American Transplant Congress
HLA Antibody Clonality and Epitopes Dictate Complement Activation.
Background: Alloimmunization results in production of polyclonal donor specific antibodies (DSA) against human leukocyte antigens (HLA), which mediate endothelial cell activation, leukocyte recruitment, and complement…2016 American Transplant Congress
Concordance Between Pancreatic Rejection and Kidney Rejection and Kidney Survival in Simultaneous Pancreas Kidney Transplantation.
Transplant Nephrology, Indiana University, Indianapolis, IN.
Purpose: It is not known whether pancreas rejection is associated with increased kidney rejection. Also, it is not known whether pancreas survival affects kidney and…2016 American Transplant Congress
Validation of SUITO Index and C-Peptide/Glucose Creatinine Ratio as Convenient Tools for the Evaluation of the Short and Long-Term Islet Allograft Function.
Background: Mixed Meal Tolerance Test (MMTT) together with the beta-score are standard tools to evaluate beta-cell function after islet transplantation but utilization of the test…
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