Am J Transplant, Volume 16, Suppl 3 Archives - Page 45 of 180 - ATC Abstracts

2016 American Transplant Congress
Graft Outcomes in Pediatric Kidney Transplants Are Better with Laparoscopic Donor Nephrectomy and High Volume Centers.
J. Burg,¹ D. Scott,¹ K. Roayaie,¹ E. Maynard,¹ J. Barry,² C. Enestvedt.¹
¹Abdominal Organ Transplantation, OHSU, Portland, OR; ²Urology, OHSU, Portland, OR.
Purpose Initial reports for pediatric kidney recipients suggested superior outcomes for open donor (ODN) compared to laparoscopic donor nephrectomy (LDN). Current outcomes based on donor…
2016 American Transplant Congress
Hypothermic Machine Perfusion Is Also Beneficial for Deceased Donor Kidneys When Cold Ischemic Time Is Short and a Short Cold Ischemic Time Is Also Beneficial When Kidneys Are Machine Perfused.
J. Kox,¹ C. Moers,² D. Monbaliu,³ A. Strelniece,⁴ J.-W. Treckmann,⁵ I. Jochmans,³ H. Leuvenink,² L. van Heurn,¹ J. Pirenne,³ A. Paul,⁵ R. Ploeg.^2,6
¹Dept. of Surgery, Maastricht University Medical Center, Maastricht, Netherlands; ²Dept. of Surgery, University Medical Center Groningen, Groningen, Netherlands; ³Abdominal Transplant Surgery, University Hospital Leuven, Leuven, Belgium; ⁴Eurotransplant, Leiden, Netherlands; ⁵General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany; ⁶Oxford Transplant Centre, Oxford, United Kingdom.
IntroductionHypothermic machine perfusion (HMP) of deceased donor kidneys is associated with better outcome compared to static cold storage (SCS). It is generally assumed that HMP…
2016 American Transplant Congress
Profiling Immunologic Risk for Acute Rejection in Liver Transplantation: Recipient Age Is a Robust Risk Factor.
M. Kueht, R. Cotton, C. O'Mahony, J. Goss, A. Rana.
Surgery, Division of Abdominal Transplantation and Hepatobiliary Surgery, Balyor College of Medicine, Houston, TX.
Profiling the immunologic risk for acute rejection in liver transplantation (OLT) may allow for selection immunosuppression (IS) target ranges appropriate to risk levels, all with…
2016 American Transplant Congress
Pre-Transplant Bariatric Surgery and One-Year Graft Loss Risk in Kidney Transplants.
G. Mour, J. Zhang, Z. Su, D. Taber, P. Mauldin, T. Srinivas.
MUSC, Charleston.
Background: Several centers recommend bariatric surgery (BS) pre-transplantation (pre-Tx) with arbitrary BMI cutoffs. The effects of BS on Tx outcome are unclear. We studied the…
2016 American Transplant Congress
Initial Experience Treating Hepatitis C Positive Kidney Transplant Recipients with Non-Interferon-Containing Regimens: Successes and Challenges.
M. Aull, A. Watkins, J. Kim, K. Rhee, D. Dadhania, J. Lee, S. Kapur.
Weill Cornell Medical College, New York, NY.
Historically, treatment of hepatitis C virus (HCV) infection with interferon-based regimens after kidney transplantation has been associated with risk of rejection & graft loss. Direct…
2016 American Transplant Congress
Gsk3β Regulates Macrophage Pro-Inflammatory Immune Activation via AMPK-Mediated Induction of Small Heterodimer Partner (SHP).
H. Zhou,^1,2 J. Zhu,^1,3 S. Yue,¹ R. Busuttil,¹ J. Kupiec-Weglinski,¹ X. Wang,² Y. Zhai.¹
¹Surgery, David Geffen School of Medicine-University of California-Los Angeles, LA, CA; ²Liver Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, China; ³Liver Surgery, Renji Hospital, Shanghai, China.
Background & AimsAlthough glycogen synthase kinase 3 β (Gsk3β) has been found to play key roles in ischemia and reperfusion injuries (IRI) of different organs,…
2016 American Transplant Congress
Blockade of the ASC Coreceptor Enhances Hematopoietic Stem Cell Engraftment.
R. Elahimehr, S. Kasimsetti, A. Shigeoka, D. McKay.
UCSD, San Diego.
Purpose: HSC engraftment is essential for successful bone marrow transplantation, and successful HSC engraftment allows for induction of tolerance to solid organ allografts. Engrafted HSCs…
2016 American Transplant Congress
Donor-Derived Toll-Like Receptor-Dependent Intravascular Monocytes Cause Primary Lung Graft Dysfunction.
S. Chiu, Z. Zheng, H. Sun, M. DeCamp, Jr, G. Budinger, H. Perlman, A. Misharin, A. Bharat.
Northwestern University, Chicago, IL.
Purpose: Neutrophils mediate primary lung allograft dysfunction (PGD), the predominant cause of early graft loss following lung transplant. The mechanisms of neutrophil infiltration remain incompletely…
2016 American Transplant Congress
Obesity Is Associated with Increased Risk of ESRD Among Living Kidney Donors.
J. Locke,¹ C. Lewis,¹ R. Reed,¹ V. Kumar,¹ D. Sawinski,² A. Massie,³ P. MacLennan,¹ R. Mannon,¹ R. Gaston,¹ D. Segev.³
¹School of Medicine, University of Alabama at Birmingham, Birmingham, AL; ²School of Medicine, University of Pennsylvania, Philadelphia, PA; ³School of Medicine, Johns Hopkins University, Baltimore, MD.
Background: Living kidney donor (LKD) demographics have changed, and transplant centers have relaxed selection criteria to include LKDs who are obese. Prior studies of LKDs…
2016 American Transplant Congress
Kidney Donor Profile Index Trend Analyses.
D. Vikraman, K. Ravindra, S. Sanoff, W. Irish, U. Patel, D. Sudan.
Surgery, Duke University Medical Center, Durham, NC.
IntroductionIn spite of improved outcomes associated with the usage of extended criteria donor (ECD) kidneys, the number of kidney transplants (KT) using this donor population…