ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    The Impact of Pre-Transplant Infections on Post-Liver Transplant Outcomes.

    S. Ngo, J. Levitsky, M. Ison.

    Divisions of Infectious Diseases, Hematology and Organ Transplantation, Northwestern University Feinberg School of Medicine, Chicago, IL.

    Background: Pre- and Post-liver transplant infections are a common cause of morbidity and mortality in orthotopic liver transplant (OLT) patients. How pre-transplant infections affect early…
  • 2016 American Transplant Congress

    Financial Burdens and Coping Mechanisms of Living Kidney Donors.

    S. Li,1 C. Thiessen,1 J. Gannon,1 D. Dobosz,1 D. Gray,3 A. Mussell,3 K. Kennedy,2 P. Reese,3 E. Gordon,1 S. Kulkarni.2

    1Yale U, New Haven; 2Northwestern U, Chicago; 3U Pennsylvania, Philadelphia.

    BackgroundFinancial disincentives remain a major barrier to increasing rates of living kidney donation. A recent study found that 96% of living kidney donors (LKD) reported…
  • 2016 American Transplant Congress

    Efficacy and Renal Function in Kidney Transplant Recipients Receiving Tacrolimus (TAC)-Based Immunosuppressive Regimens in Combination with Everolimus (EVR) versus Mycophenolate (MPA).

    A. Brigido, H. Tedesco, C. Felipe, M. Cristelli, M. Franco, J. Medina-Pestana.

    Nephrology Division, Hospital do Rim - UNIFESP, Sao Paulo, Brazil.

    Acute rejection and renal function are associated with long-term renal allograft survival. We evaluated these outcomes in patients receiving reduced TAC exposure combined with EVR…
  • 2016 American Transplant Congress

    Induction Therapy with Rabbit Antithymocyte Globulin (rATG, Thymoglobulin®) vs Basiliximab After Kidney Transplantation: A Health Economic Analysis from a German Perspective.

    L. Cremaschi,1 R. Thissen,2 T. Benzing,2 M. Wiesener,3 N. Zink,3 T. Paivanas,4 J. Reitan,4 M. Gallagher,5 F. Thaiss.1

    1Univ. Hospital Eppendorf UKE, Hamburg, Germany; 2Univ. Hospital Cologne, Colgone, Germany; 3Univ. Hospital Erlangen-Nürnberg, Erlangen, Germany; 4RJM Group, LLC, Washington, DC; 5Sanofi-Aventis US, Cambridge, MS.

    Study objective. A health economic analysis was undertaken to quantify the economic consequences of acute rejection and serious adverse events in patients receiving induction with…
  • 2016 American Transplant Congress

    The Impact of Body Mass Index > 35 on Kidney Transplant Outcomes: A Systematic Review.

    D. Walczak, E. Benedetti.

    Organ Transplant, University of Illinois Hospital and Health Sciences System, Chicago, IL.

    Background: The increased prevalence of obesity (BMI > 30) among adults in the United States over the last two decades is reflected in the number…
  • 2016 American Transplant Congress

    Microarray Analysis of Transbronchial and Mucosal Biopsies in Lung Transplant Recipients Detects Molecular Changes of T-Cell Mediated Inflammation.

    K. Halloran,1 J. Chang,2 V. Ramassar,2 J. Weinkauf,1 A. Kapasi,1 D. Lien,1 J. Reeve,2 P. Halloran.1,2

    1Medicine, University of Alberta, Edmonton, Canada; 2Alberta Transplant Applied Genomics Centre, University of Alberta, Edmonton, Canada.

    Purpose: The main diagnostic platform for rejection in lung transplant recipients is histology of transbronchial biopsies (TBB), a test with a poor performance and safety…
  • 2016 American Transplant Congress

    Machine Perfusion (MP) at 21[deg]C Simulates Hibernation Metabolic Pathways in a Non-Hibernator Mammal.

    B. Banan, S. Dobrowolski, G. Michalopoulos, P. Fontes.

    University of Pittsburgh, Pittsburgh.

    Background: Hibernation is a complex and multi stage process that leads to unique metabolic changes over an extended period of time. Regulatory genes and transcription…
  • 2016 American Transplant Congress

    Ledipasvir/Sofosbuvir (LDV/SOF) for 12 or 24 Weeks Is Safe and Effective in Kidney Transplant Recipients with Chronic Genotype 1 or 4 HCV Infection.

    S. Pol,1 A. Aghemo,2 L. Lin,3 R. Hyland,3 C. Yun,3 J. Spellman,3 M. Natha,3 D. Brainard,3 J. McHutchison,3 M. Bourlière,4 M. Peck-Radosavljevic,6 M. Michael,5 M. Colombo.2

    1Hopital Cochin, Paris, France; 2Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy; 3Gilead Sciences Inc, Foster City; 4Hôpital Saint Joseph, Marseilles, France; 5Hannover Medical School, Hannover, Germany; 6Medical University of Vienna, Vienna, Austria.

    Background and Aims: Interferon (IFN) and ribavirin (RBV) for the treatment of chronic hepatitis C (HCV) in kidney transplant recipients is complicated by the risk…
  • 2016 American Transplant Congress

    Mapping Heterogeneity in Antibody-Mediated Rejection Using Molecular Phenotypes and Archetype Analysis.

    J. Reeve,1 P. Halloran.1,2

    1Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada; 2Medicine, University of Alberta, Edmonton, AB, Canada.

    Archetype analysis is a method for identifying new relationships among samples without subdividing them into classes, finding a limited number of archetypical cases and calculating…
  • 2016 American Transplant Congress

    Predictors of eGFR Slope at One Year in Kidney Transplants – A Big Data Approach.

    J. Zhang, Z. Su, D. Taber, J. Marsden, W. Moran, P. Mauldin, T. Srinivas.

    MUSC, Charleston.

    Background: Estimated glomerular filtration rate (eGFR), a predictor of graft loss (GL) in kidney transplantation could inform intervention. National data yield eGFRs at fixed time…
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