ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Tool to Assess Risk of Non-Adherence in Renal Transplant Candidates.

    T. Kaiser,1 K. Daley,2 L. Dick,2 L. Deye,2 N. Parrish,2 J. Huff,2 A. Govil,1 B. Abu Jawdeh,1 G. Mogilishetty,1 R. Alloway,1 E. Woodle.1

    1Medicine, University of Cincinnati, Cincinnati; 2Transplant, University of Cincinnati Medical Center, Cincinnati, OH.

    Nonadherence (NA) is likely the primary driver of late graft loss and was found to occur in 59% of renal transplant (RTx) patients at our…
  • 2016 American Transplant Congress

    Genetic TIM-4 Deletion Promotes Immunoregulatory Tissue-Resident Macrophage Survival and Lowers the Barrier to Cardiac Allograft Tolerance.

    T. Thornley,1 P. Kyriazis,1 K. Agarwal,1 Z. Fang,1 L. Ma,1 V. Chipashvili,1 M. Koulmanda,1,2 T. Strom.1,2

    1Medicine, Harvard Medical School and Beth Israel Deaconess Medical Center, Boston, MA; 2Surgery, Harvard Medical School and Beth Israel Deaconess Medical Center, Boston, MA.

    We report that the CD169+TIM-4+ tissue-resident macrophage (TRM) subset is the dominant tissue-resident leukocyte in skin, heart, and pancreas from C57BL/6 mice and skin and…
  • 2016 American Transplant Congress

    Primary Graft Failure following Cardiac Transplantation Is Associated with Elevated Pre-Transplant Levels of Pro-Inflammatory Factors.

    D. Chatterjee,1 K. Clerkin,1 K. Rogers,1 D. Mancini,1 Y. Naka,1 H. Takayama,2 K. Takeda,2 P. Colombo,2 G. Vlad,3 R. Vasilescu,3 B. Levin,4 M. Farr,1 S. Restaino,1 E. Zorn.1

    1Columbia University Medical Center, NY; 2Surgery, Columbia University Medical Center, NY; 3Pathology & Cell Biology, Columbia University Medical Center, NY; 4Biostatistics, Columbia University Medical Center, NY.

    Primary graft failure (PGF) is defined as severe ventricular dysfunction immediately following heart transplantation (HTx) requiring temporary mechanical circulatory support (MCS) such as VA ECMO…
  • 2016 American Transplant Congress

    Latest VCA Statistics in the U.S.

    W. Cherikh,1 H. McGehee,1 C. Wholley,1 L. Levin,2 S. McDiarmid.3

    1United Network for Organ Sharing, Richmond, VA; 2Hosp of the Univ of Pennsylvania, Philadelphia, PA; 3UCLA Medical Center, Los Angeles, CA.

    Background. On July 3, 2014, the Organ Procurement and Transplantation Network/United Network for Organ Sharing (OPTN/UNOS) was charged with the oversight of Vascularized Composite Allograft…
  • 2016 American Transplant Congress

    Examining the Risk for Post-Transplant Viral Infections and Lymphoproliferative Disorder (PTLD) in Kidney Transplant Patients (Pts) Receiving Calcineurin Inhibitor-Based Immunosuppression (CNI-IS) Compared to Belatacept (CTLA4Ig).

    B. Shin, J. Choi, J. Kahwaji, S. Ge, D. Thomas, A. Vo, O. Galera, R. Villicana, A. Peng, S. Jordan, M. Toyoda.

    Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA.

    Introduction: CTLA4Ig is a novel IS agent that acts through costimulatory blockade of T-cells and obviates the need for CNI. Despite benefits in improving renal…
  • 2016 American Transplant Congress

    Impact of the Kidney Allocation System with Deceased Donor Kidney Utilization at the DSA Level.

    W. Ally,2 C. Saunders,1 K. Brayman,2 A. Agarwal.2

    1Lifenet Health, Virginia Beach, VA; 2University of Virginia Health System, Charlottesville, VA.

    Background: In December 2014, UNOS implemented broad sweeping changes in the new Kidney Allocation System (KAS). Recent summary reports by UNOS suggest that on a…
  • 2016 American Transplant Congress

    25-Hydroxyvitamin D Insufficiency Is Associated with Higher Risk of BK Virus Re-Activation After Kidney Transplantation.

    N. Elfadawy,1 S. Flechner,2 E. Poggio,2 B. Stephany,2 R. Fatica,2 J. Schold,2 S. Mossad.2

    1Internal Medicine, Case Western Reserve University, Cleveland, OH; 2Cleveland Clinic, Cleveland, OH.

    BACKGROUND: The past decade has seen increased interest in vitamin D, as new data suggest that it plays a role in the immune system. The…
  • 2016 American Transplant Congress

    Utility in Treating Renal Failure in End-Stage Liver Disease with Simultaneous Liver-Kidney Transplantation.

    X. Cheng,1 M. Stedman,1 W. Kim,2 J. Tan.1

    1Division of Nephrology, Stanford University, Palo Alto, CA; 2Division of Gastroenterology and Hepatology, Stanford University, Palo Alto, CA.

    The number of simultaneous liver-kidney transplants (SLKT) for end-stage liver disease (ESLD) with renal failure is rising. The overall utility of kidneys used in this…
  • 2016 American Transplant Congress

    Clinical Prediction Tool to Guide Referral of Elderly Dialysis Patients for Kidney Transplant Evaluation.

    L.-X. Chen,1 M. Josephson,1 N. Stankus,1 K. Campbell,1 D. Hedeker,2 M. Saunders.1

    1Department of Medicine, University of Chicago, Chicago, IL; 2Department of Public Health Sciences, University of Chicago, Chicago, IL.

    Background: Adults over 70 years old are the fastest growing segment of the end stage renal disease (ESRD) population. Due to substantial variation in co-morbidities…
  • 2016 American Transplant Congress

    Mortality and Graft Loss Attributable to Readmission Following Kidney Transplantation.

    E. King, M. Bowring, L. Kucirka, M. McAdams-DeMarco, A. Massie, D. Segev.

    Surgery, Johns Hopkins University, School of Medicine, Baltimore, MD.

    BACKGROUND: Early hospital readmission (EHR) following kidney transplantation (KT) is independently associated with graft loss and mortality. Prior work assumes that this association is constant…
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