ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Lipid Metabolism and Preservation of Discarded Steatotic Human Livers Using 24 Hours Ex-Vivo Normothermic Machine Perfusion.

    Q. Liu, A. Nassar, G. Iuppa, B. Soliman, L. Buccini, M. Blum, T. Okamoto, T. Uso, A. Bennett, W. Baldwin, K. Abu-Elmagd, J. Fung, C. Miller, C. Quintini.

    Cleveland Clinic, Cleveland, OH.

    One primary reason to discard donor livers after procurement is severe steatosis. The impact of normothermic machine perfusion (NMP) on lipid metabolism and preservation of…
  • 2016 American Transplant Congress

    Outcomes in Black vs Non-Black Patients Administered Belatacept (Bela) or Cyclosporine (CsA) in BENEFIT.

    F. Vincenti,1 J. Medina Pestana,2 M. Abouljoud,3 B. Bresnahan,4 V. Duro Garcia,5 L. Mulloy,6 K. Rice,7 L. Rostaing,8 C. Zayas,9 K. Calderon,10 U. Meier-Kriesche,10 M. Polinsky,10 H. Zhao,10 C. Larsen.11

    1UCSF, San Francisco; 2Hosp do Rim, Sao Paulo, Brazil; 3Henry Ford Hosp, Detroit; 4Med Coll of Wisconsin, Milwaukee; 5Hospital Dom Vicente Scherer, Porto Alegre, Brazil; 6Georgia Regents Univ, Augusta; 7Baylor Univ Med Ctr, Dallas; 8Univ Hosp and INSERM U563, IFR-BMT, Toulouse, France; 9Piedmont Hosp, Atlanta; 10BMS, Lawrenceville; 11Emory Univ Transplant Center, Atlanta.

    Studies consistently show worse outcomes for black vs non-black kidney transplant recipients. At 7 yrs post-transplant in BENEFIT, bela was associated with superior graft survival…
  • 2016 American Transplant Congress

    Acute Rejection, New-Onset Diabetes After Transplant and Transplant Outcomes in Pediatric Kidney Recipients: Analysis of the Organ Procurement and Transplant Network/United Network for Organ Sharing (OPTN/UNOS) Database.

    A. Mehrnia, T. Le, T. Tamer, S. Bunnapradist.

    Nephrology, UCLA, Los Angeles, CA.

    Introduction Our objective was to identify the associations of new-onset diabetes after transplant (NODAT) and acute rejection (AR) in predicting patient mortality and transplant failure…
  • 2016 American Transplant Congress

    Adding an Antimetabolite to a Calcineurin-Inhibitor-Based Immunosuppression Regimen Leads to Improved Native Renal Function After Liver Transplantation.

    A. Karim, D. Conway, G. Leverson, J. Mezrich, L. Fernandez, A. D'Alessandro, D. Foley.

    Surgery, University of Wisconsin, Madison, WI.

    Background: Nephrotoxic side effects of calcineurin inhibitors (CNI) have been well established. The addition of anti-metabolites (AM) to CNI-based immunosuppression (IS) regimens has been proposed…
  • 2016 American Transplant Congress

    Novel Approaches to Medication Teaching in Solid Organ Transplantation.

    D. Tsapepas, N. Jandovitz, S. Dulanya, D. Salerno, S. Hammad, P. Jordan.

    NewYork-Presbyterian Hospital, Columbia University, New York.

    Technology has become a fundamental part of our daily lives; mobile application (app) technologies enhance a healthcare providers ability to deliver patient-centered care. Solid organ…
  • 2016 American Transplant Congress

    Conversion to Once-Daily Tacrolimus in Stable Pediatric Liver Transplantation Recipients.

    N. Lee, S. Lee, C.-W. Cho, J. Lee, J. Lee, J. Kim, G.-S. Choi, C. Kwon, J.-W. Joh, S.-K. Lee.

    Department of Surgery Organ Transplant Center, Samsung Medical Center, Seoul, Republic of Korea.

    Purpose: Pediatric patients are known to have lower compliance than adult patients. Once-daily formulation of tacrolimus may increase compliance in pediatric liver transplant recipients. The…
  • 2016 American Transplant Congress

    Combined Liver-Kidney Transplantation in Children: Long-Term Follow-Up in 27 Children.

    M. Kemper,1 B. Nashan,2 L. Fischer,2 F. Brinkert.1

    1Pediatrics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; 2Hepatobiliary and Transplantation Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

    Combined liver and kidney transplantation (CLKT) is an important treatment option for patients suffering from diseases like autosomal recessive polycystic kidney disease (ARPKD) or primary…
  • 2016 American Transplant Congress

    Nuclear Factor of Activated T-Cells Post-Renal Transplant.

    K. Tornatore,1,4 K. Attwood,2 O. McGuire,3 K. O'Loughlin,3 R. Venuto,4 H. Minderman.3

    1Translational Pharmacology Research Center, School of Pharmacy, Buffalo; 2Biostatistics, School of Public Health, Buffalo; 3Flow Cytometry Laboratory, Roswell Park Cancer Institute, Buffalo; 4Medicine, School of Medicine, University at Buffalo, Buffalo.

    Background: Nuclear Factor of Activated T-cells (NFAT1) is a transcription factor regulating the expression of key targets involved with cellular immune function. Calcineurin is a…
  • 2016 American Transplant Congress

    Pneumocystis jirovecii Pneumonia: Late and Serious Complication Among Kidney Transplant Recipients.

    L. Viana, T. Sandes, M. Cristelli, A. Oliveira, D. Santos, H. Tedesco-Silva, J. Medina-Pestana.

    HOSPITAL DO RIM-UNIFESP, São Paulo, Brazil.

    We report 50 confirmed PJP cases that occurred in kidney transplant patients between 06/16/2011 and 10/17/2015 in a single center.In the studied period, there were…
  • 2016 American Transplant Congress

    Clinical Significance of Mycophenolic Acid Therapeutic Drug Monitoring in Kidney Transplant Recipients.

    C.-D. Kim, J.-H. Cho, K. Kim, M. Kim, W. Do, Y. Yang, T. Yim, I. Hwang, J.-H. Lee, H.-Y. Jung, J.-Y. Choi, S.-H. Park, Y.-L. Kim.

    Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea.

    Background: Mycophenolic acid (MPA) is a widely used immunosuppressant to prevent acute rejection in kidney transplant recipients (KTRs). However, clinical significance of MPA therapeutic drug…
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