Am J Transplant, Volume 16, Suppl 3 Archives - Page 42 of 180 - ATC Abstracts

2016 American Transplant Congress
A Pathway to Belatacept Monotherapy: Alemtuzumab, Belatacept and Rapamycin for Kidney Transplantation.
A. Guasch,¹ H. Xu,² A. Mehta,¹ A. Ghali,¹ S. Mead,¹ H. Gebel,¹ R. Bray,¹ C. Larsen,¹ T. Pearson,¹ A. Kirk.²
¹Emory Transplant Center, Atlanta, GA; ²Duke University, Durham, NC.
Kidney transplantation remains limited by toxicities of calcineurin inhibitors (CNIs) and steroids. Belatacept is a less toxic CNI alternative delivered by monthly intravenous infusion, but…
2016 American Transplant Congress
IgG Dilutions, Subclasses, C1q, and IgM: Determining Relevant Testing for De Novo DSA and Outcome Prediction.
M. Everly,¹ L. Rebellato,² C. Haisch,² K. Briley,² P. Bolin,² S. Kendrick,³ C. Morgan,² A. Maldonado,⁴ A. Nguyen,¹ P. Terasaki.¹
¹Terasaki Foundation Laboratory, Los Angeles; ²East Carolina University, Greenville, NC; ³Eastern Nephrology Associates, Greenville, NC; ⁴Vidant Medical Center, Greenville, NC.
Numerous publications have shown secondary antibody testing of IgG (subclasses, C1q, etc) in de novo DSA (dnDSA) positive patients may have clinical relevance. Herein, we…
2016 American Transplant Congress
Nondirected Kidney Donation – Donating More Than a Kidney.
C. Jacobs,¹ J. Wiseman,¹ D. Berglund,¹ D. Larson,¹ C. Garvey,¹ M. Vogues,¹ S. Rein,¹ O. Sanchez,¹ C. Radecki Breitkopf,² H. Ibrahim,¹ A. Matas.¹
¹U of MN, Mpls; ²Mayo Clinic, Rochester.
Little is known about donation-related out-of-pocket costs incurred by NDD. For NDD, we studied: resources used to cover these costs; level of stress due to…
2016 American Transplant Congress
Increased Access to Transplantation of Highly Sensitized Patients Facilitated by the New Kidney Allocation System.
A. Colovai, M. Ajaimy, C. Savchik, S. Chan, P. Masiakos, J. Rocca, E. Akalin.
Abdominal Transplant, Montefiore Medical Center, Bronx, NY.
The purpose of our study was to evaluate the impact of the new kidney allocation system (KAS 2014) on the access to transplantation of HLA…
2016 American Transplant Congress
Molecular Assessment of Kidney Transplant Biopsies Performs Similarly in Medulla and Cortex.
K. Madill-Thomsen,¹ J. Reeve,¹ G. Bohmig,² F. Eskandary,² P. Halloran.^1,3
¹Alberta Transplant Applied Genomics Center, Edmonton, AB, Canada; ²Department of Nephrology and Dialysis, Medical University of Vienna, Vienna, Austria; ³Department of Medicine, Division of Nephrology and Transplant Immunology, University of Alberta, Edmonton, AB, Canada.
Histologic assessment of kidney biopsies is usually unable to interpret medulla, but molecular changes associated with rejection likely occur in both medulla and cortex. Analysis…
2016 American Transplant Congress
Pre-Transplant Panel of Reactive T Cells (PRT) as an Independent Predictor of 2-Year Kidney Graft Function.
I. Gandolfini,¹ E. Crespo,² M. Baweja,¹ U. Maggiore,³ P. Cravedi,¹ P. Heeger,¹ O. Bestard.²
¹Icahn School of Medicine, New York, NY; ²Bellvitge University Hospital, Barcelona, Spain; ³University of Parma, Parma, Italy.
Background: The ELISPOT PRT quantifies frequencies of IFN-g-producing effector/memory T cells reactive against a panel of allogenic stimulators. In contrast to the donor-reactive ELISPOT, it…
2016 American Transplant Congress
Global Kidney Exchange.
M. Rees,¹ T. Dunn,¹ S. Rees,¹ J. Rogers,¹ L. Reece,¹ A. Roth,² C. Kuhr,¹ O. Ekwenna,¹ D. Fumo,¹ K. Krawiec,³ S. Jain,¹ C. Marsh,¹ M. Tan,¹ S. Paloyo.⁴
¹Alliance for Paired Kidney Donation, Perrysburg; ²Stanford University, Palo Alto; ³Duke University, Durham; ⁴Philippine General Hospital, Manila, Philippines.
Introduction: Instead of thinking of the developing world as a place where there are desperate people who will sell their kidneys for money, we propose…
2016 American Transplant Congress
Predictors of Postoperative Cardiovascular Complications Until Three Months After Kidney Transplantation.
M. Slot,^1,2 J. van de Wetering,¹ M. Kho,¹ M. Betjes,¹ J. Roodnat.¹
¹Nephrology, Erasmus Medical Center, Rotterdam, Netherlands; ²Nephrology, VU Medical Center, Amsterdam, Netherlands.
Purpose: To identify factors involved in cardiac events within three months after renal transplantation.Methods: We conducted a chart review for all renal transplants (RT) performed…
2016 American Transplant Congress
Simulating Alternative Bayesian Criteria to Identify Transplant Center Performance Outliers.
J. Schold,¹ C. Miller,¹ M. Henry,² L. Buccini,¹ S. Flechner,¹ D. Goldfarb,¹ E. Poggio,¹ K. Andreoni.³
¹Cleveland Clinic, Cleveland, OH; ²Ohio State University, Columbus, OH; ³University of Florida, Gainesville, FL.
The newly constructed Bayesian models to evaluate transplant center performance were implemented in 2014. The rates and impact of the assumptions used for flagging centers…
2016 American Transplant Congress
Renal Fibroblast Activation and Survival by Anti-MHC Class I Antibody: The Role of mTOR Signaling Pathway.
J. Chen, A. Zmijewska, R. Mannon.
Medicine/Surgery, University of Alabama at Birmingham, Birmingham, AL.
Background: Antibody-mediated injury (AMI) is an important contributor to late kidney allograft loss, and is accompanied by interstitial fibrosis (IF) and tubular atrophy (TA). However,…