ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Acute Rejection, New-Onset Diabetes After Transplant and Transplant Outcomes in Pediatric Kidney Recipients: Analysis of the Organ Procurement and Transplant Network/United Network for Organ Sharing (OPTN/UNOS) Database.

    A. Mehrnia, T. Le, T. Tamer, S. Bunnapradist.

    Nephrology, UCLA, Los Angeles, CA.

    Introduction Our objective was to identify the associations of new-onset diabetes after transplant (NODAT) and acute rejection (AR) in predicting patient mortality and transplant failure…
  • 2016 American Transplant Congress

    Adding an Antimetabolite to a Calcineurin-Inhibitor-Based Immunosuppression Regimen Leads to Improved Native Renal Function After Liver Transplantation.

    A. Karim, D. Conway, G. Leverson, J. Mezrich, L. Fernandez, A. D'Alessandro, D. Foley.

    Surgery, University of Wisconsin, Madison, WI.

    Background: Nephrotoxic side effects of calcineurin inhibitors (CNI) have been well established. The addition of anti-metabolites (AM) to CNI-based immunosuppression (IS) regimens has been proposed…
  • 2016 American Transplant Congress

    Novel Approaches to Medication Teaching in Solid Organ Transplantation.

    D. Tsapepas, N. Jandovitz, S. Dulanya, D. Salerno, S. Hammad, P. Jordan.

    NewYork-Presbyterian Hospital, Columbia University, New York.

    Technology has become a fundamental part of our daily lives; mobile application (app) technologies enhance a healthcare providers ability to deliver patient-centered care. Solid organ…
  • 2016 American Transplant Congress

    Conversion to Once-Daily Tacrolimus in Stable Pediatric Liver Transplantation Recipients.

    N. Lee, S. Lee, C.-W. Cho, J. Lee, J. Lee, J. Kim, G.-S. Choi, C. Kwon, J.-W. Joh, S.-K. Lee.

    Department of Surgery Organ Transplant Center, Samsung Medical Center, Seoul, Republic of Korea.

    Purpose: Pediatric patients are known to have lower compliance than adult patients. Once-daily formulation of tacrolimus may increase compliance in pediatric liver transplant recipients. The…
  • 2016 American Transplant Congress

    Combined Liver-Kidney Transplantation in Children: Long-Term Follow-Up in 27 Children.

    M. Kemper,1 B. Nashan,2 L. Fischer,2 F. Brinkert.1

    1Pediatrics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; 2Hepatobiliary and Transplantation Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

    Combined liver and kidney transplantation (CLKT) is an important treatment option for patients suffering from diseases like autosomal recessive polycystic kidney disease (ARPKD) or primary…
  • 2016 American Transplant Congress

    Nuclear Factor of Activated T-Cells Post-Renal Transplant.

    K. Tornatore,1,4 K. Attwood,2 O. McGuire,3 K. O'Loughlin,3 R. Venuto,4 H. Minderman.3

    1Translational Pharmacology Research Center, School of Pharmacy, Buffalo; 2Biostatistics, School of Public Health, Buffalo; 3Flow Cytometry Laboratory, Roswell Park Cancer Institute, Buffalo; 4Medicine, School of Medicine, University at Buffalo, Buffalo.

    Background: Nuclear Factor of Activated T-cells (NFAT1) is a transcription factor regulating the expression of key targets involved with cellular immune function. Calcineurin is a…
  • 2016 American Transplant Congress

    Pneumocystis jirovecii Pneumonia: Late and Serious Complication Among Kidney Transplant Recipients.

    L. Viana, T. Sandes, M. Cristelli, A. Oliveira, D. Santos, H. Tedesco-Silva, J. Medina-Pestana.

    HOSPITAL DO RIM-UNIFESP, São Paulo, Brazil.

    We report 50 confirmed PJP cases that occurred in kidney transplant patients between 06/16/2011 and 10/17/2015 in a single center.In the studied period, there were…
  • 2016 American Transplant Congress

    Clinical Significance of Mycophenolic Acid Therapeutic Drug Monitoring in Kidney Transplant Recipients.

    C.-D. Kim, J.-H. Cho, K. Kim, M. Kim, W. Do, Y. Yang, T. Yim, I. Hwang, J.-H. Lee, H.-Y. Jung, J.-Y. Choi, S.-H. Park, Y.-L. Kim.

    Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea.

    Background: Mycophenolic acid (MPA) is a widely used immunosuppressant to prevent acute rejection in kidney transplant recipients (KTRs). However, clinical significance of MPA therapeutic drug…
  • 2016 American Transplant Congress

    Tool to Assess Risk of Non-Adherence in Renal Transplant Candidates.

    T. Kaiser,1 K. Daley,2 L. Dick,2 L. Deye,2 N. Parrish,2 J. Huff,2 A. Govil,1 B. Abu Jawdeh,1 G. Mogilishetty,1 R. Alloway,1 E. Woodle.1

    1Medicine, University of Cincinnati, Cincinnati; 2Transplant, University of Cincinnati Medical Center, Cincinnati, OH.

    Nonadherence (NA) is likely the primary driver of late graft loss and was found to occur in 59% of renal transplant (RTx) patients at our…
  • 2016 American Transplant Congress

    Genetic TIM-4 Deletion Promotes Immunoregulatory Tissue-Resident Macrophage Survival and Lowers the Barrier to Cardiac Allograft Tolerance.

    T. Thornley,1 P. Kyriazis,1 K. Agarwal,1 Z. Fang,1 L. Ma,1 V. Chipashvili,1 M. Koulmanda,1,2 T. Strom.1,2

    1Medicine, Harvard Medical School and Beth Israel Deaconess Medical Center, Boston, MA; 2Surgery, Harvard Medical School and Beth Israel Deaconess Medical Center, Boston, MA.

    We report that the CD169+TIM-4+ tissue-resident macrophage (TRM) subset is the dominant tissue-resident leukocyte in skin, heart, and pancreas from C57BL/6 mice and skin and…
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