ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Breadth of HLA-Specific B Cell Reactivity and Frequency Assessed by a Novel Multiplex Bead Based Assay Predicts and Correlates with Rejection in Kidney Transplant Recipients.

    A. Akl, Z. Ilyas, O. Traitanon, L. Gallon, A. Tambur, M. Ansari.

    Northwestern University, Chicago.

    Introduction: Recipients with broad sensitization to HLA defined by a high percentage of Panel Reactive Antibodies (PRA) are at higher immunologic risk for poor graft…
  • 2016 American Transplant Congress

    Alemtuzumab Induction Allows Better Rejection Free Graft Survival in Comparison to Basiliximab Although with Increased Post Transplant Viral Infections.

    V. Siddagangaiah,1 H. Sharma,2 N. Lal,1 J. Rai,1 M. Howse,1 D. Ridgway,1 A. Sharma,1 A. Hammad,1 S. Mehra.1

    1Renal Transplant Surgery, Royal Liverpool and Broadgreen University Hospital, Liverpool, United Kingdom; 2Transplant Surgery, Manchester Royal Infirmary, Manchester, United Kingdom.

    Introduction: 3C study concluded that in comparison to basiliximab, alemtuzumab induction reduces the risk of biopsy proven acute rejection (BPAR) in renal transplant recipients. In…
  • 2016 American Transplant Congress

    Thoracic Simulated Allocation Modeling (TSAM) of Broader Sharing.

    M. Colvin,1 M. Skeans,1 L. Robbins Callahan,2 L. Edwards,2 J. Zeglin,1 S. Silvestry,3 R. Davies,4 M. Farr,5 A. Israni,1 J. Rogers.6

    1SRTR, Minneapolis, MN; 2UNOS, Richmond, VA; 3Florida Hospital Transplant Institute, Orlando, FL; 4Nemours/A.I. duPont Hospital for Children, Wilmington, DE; 5Columbia University Medical Center, New York, NY; 6Duke University, Durham, NC.

    Heart allocation policy (OPTN policy 6) is in development. The Heart Subcommittee of the OPTN Thoracic Committee developed a 6-tiered medical urgency algorithm, then investigated…
  • 2016 American Transplant Congress

    Matrix Metalloproteinase-2 (MMP-2) Activity Protects Against Hepatic Ischemia Reperfusion Injury Through MMP-9-Dependent and MMP-9-Independent Mechanisms.

    S. Duarte, P. Matian, H. Kato, R. Busuttil, A. Coito.

    The Dumont-UCLA Transplant Center, Los Angeles.

    Matrix Metalloproteinases (MMPs) are a family of proteinases with key roles in tissue homeostasis, inflammation and repair. We have recently shown that MMP-9 and MMP-2,…
  • 2016 American Transplant Congress

    Bioinformatic Analysis of Pathways Mediating Clusterin Functions in Kidney Cells Under Normoxia and Hypoxia.

    G. Dairi, Q. Guan, C. Collins, C. Ong, M. Gleave, C. Nguan, C. Du.

    Department of Urologic Sciences, University of British Columbia, Vancouver, BC, Canada.

    Background: Clusterin (CLU) is a chaperone-like protein and contributes to the resistance of the kidney to ischemia-reperfusion injury (IRI), however its pathways are not fully…
  • 2016 American Transplant Congress

    Mitochondrial Membrane Potential Correlates with Ischemic Injury and Kidney Graft Function in Rats.

    M. Chen, J. Huang, L. Qi, S. Kwon, R. Montgomery, Z. Sun.

    Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.

    BackgroundBoth short- and long-term outcomes of all organ transplants depend on the quality of the organ. Presently there is no completely reliable method to evaluate…
  • 2016 American Transplant Congress

    Effect of Baseline Co-Morbidity on Mortality in Living Kidney Donors – 10 Year UK Cohort Study.

    N. Krishnan,1 L. Bradbury,2 N. Raymond.1

    1Renal & Transplantation, University Hospitals Coventry & Warwickshire NHS Trust, Coventry, United Kingdom; 2Statistics, National Health Service, Organ Donation & Transplant, Bristol, United Kingdom.

    Living kidney donation has significantly improved recipient and graft survival world wide. With a move to increase these numbers further, it becomes mandatory to have…
  • 2016 American Transplant Congress

    The Safety and Efficacy of Suspended Gasless Laparoscopy Living-Donor Nephrectomy in Renal Transplantation.

    J. Tian.

    Organ Transplantation Center, Qilu Hospital of Shandong University, Jinan, China.

    BACKGROUNDS: To develop a minimally invasive surgery for the kidney transplant donor and get the no CO2 pressure condition harvested kidney, we have developed suspended…
  • 2016 American Transplant Congress

    Predicting Delayed Kidney Graft Function with Gene Expression in Preimplantation Biopsies.

    T. Mourão,1,3 K. Mine,1 E. Campos,1,3 J. Medina-Pestana,2,3 H. Tedesco-Silva,2 M. Gerbase-De Lima.

    1Immunogenetics Institute, Associação Fundo de Incentivo à Pesquisa - AFIP, São Paulo, SP, Brazil; 2Hospital do Rim e Hipertensão, Fundação Oswaldo Ramos, São Paulo, SP, Brazil; 3UNIFESP, São Paulo, SP, Brazil.

    Aiming to further the investigation of markers in pre-implantation biopsies (PIB) for the prediction of delayed graft function (DGF), we analyzed, in a different cohort…
  • 2016 American Transplant Congress

    Factors Associated with Prolonged Warm Ischemia Time Among Deceased Donor Kidney Transplant Recipients.

    A. Miller,1 B. Kiberd,1 I. Alwayn,2 S. Kim,3 K. Tennankore.1

    1Medicine, Division of Nephrology, Dalhousie University, Halifax, NS, Canada; 2Surgery, Multi Organ Transplant Program, Dalhousie University, Halifax, NS, Canada; 3Medicine, Division of Nephrology, University of Toronto, Toronto, ON, Canada.

    Prolonged warm ischemia time (the time from organ removal from cold storage to reperfusion with warm blood) is associated with graft failure and mortality among…
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