Am J Transplant, Volume 16, Suppl 3 Archives - Page 40 of 180 - ATC Abstracts

2016 American Transplant Congress
Liver Ischemia Induces Kupffer Cell Necroptosis to Facilitate Liver Inflammatory Immune Activation.
S. Yue,¹ H. Zhou,^1,2 R. Busuttil,¹ J. Kupiec-Weglinski,¹ X. Wang,² Y. Zhai.¹
¹Surgery, David Geffen School of Medicine-University of California-Los Angeles, Los Angeles, CA; ²Liver Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, China.
Background & AimsAlthough mechanisms of liver immune activation against ischemia reperfusion injury (IRI) have been studied extensively, cellular bases have yet to be fully defined…
2016 American Transplant Congress
Allograft TLR4 Receptor Signaling Induces Specific Early Inflammatory Events in Promotes Allografts Subjected to Prolonged Cold Ischemic Storage.
T. Yagisawa, N. Kohei, D. Kish, R. Fairchild.
Dept. Immunology and Glickman Urological Institute, Cleveland Clinic, Cleveland, OH.
Engagement of Toll-like receptors (TLR) by endogenous danger-associated molecular pattern ligands contributes to the intensity of tissue inflammation, including the inflammation generated during ischemia-reperfusion injury…
2016 American Transplant Congress
Anti-LG3 Antibodies Enhance Renal Microvascular Rarefaction, Fibrosis and Dysfunction Associated with Ischemia-Reperfusion Injury.
B. Yang,^1,3 K. Hamelin,^1,3 M. HÉnault-Rondeau,^1,3 N. Patey,^1,2,3 J. Turgeon,^1,3 S. Lan,^1,3 L. Pomerleau,¹ J. Peng,¹ J. Tremblay,¹ M. DieudÉ,^1,3 M.-J. HÉbert,^1,3 H. Cardinal.^1,3
¹Research Centre, Centre Hospitalier de l'Université de Montréal (CRCHUM), Montreal, QC, Canada; ²Department of Pathology, CHU Ste-Justine, Montreal, QC, Canada; ³Canadian National Transplant Research Program, CNTRP, Canada.
Delayed graft function (DGF) is associated with decreased kidney graft survival. We have shown that pre-transplant anti-LG3 autoantibodies were associated with increased risk of DGF…
2016 American Transplant Congress
Ineligible: Attitudes and Follow-Up of Individuals Ruled Out of Living Kidney Donation.
D. Dobosz,¹ C. Thiessen,¹ J. Gannon,¹ S. Li,¹ K. Kennedy,² D. Gray,³ A. Mussell,³ E. Gordon,² S. Kulkarni,¹ P. Reese.³
¹Yale U, New Haven; ²Northwestern U, Chicago; ³U Pennsylvania, Philadelphia.
Background: Little is known about the experiences of individuals who begin living kidney donor (LKD) evaluation but are turned down due to ineligibility. We assessed…
2016 American Transplant Congress
Effect of Baseline Proteinuria on Long- and Short-Term Outcomes in Live Kidney Donors – 10 Year U.K Cohort Study.
N. Krishnan,¹ L. Bradbury,² N. Raymond.¹
¹Renal & Transplantation, University Hospitals Coventry & Warwickshire NHS Trust, Coventry, United Kingdom; ²Statistics, National Health Service, Organ Donation & Transplant, Bristol, United Kingdom.
Living kidney donation has significantly improved recipient and graft survival world wide. It is importanat to have a better understanding of the outcomes and risks…
2016 American Transplant Congress
Risk Stratification for Optimized Utilization of Deceased Donor Kidneys with Acute Kidney Injury by KDIGO Criteria.
B. Yu,¹ T. Koo,² J. Lee,³ J. Yang,² J. Ha,⁴ C. Ahn,¹ Y. Kim,¹ H. Lee.¹
¹Internal Medicine, Seoul National University Hospital, Seoul, Korea; ²Transplantation Center, Seoul National University Hospital, Seoul, Korea; ³Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Korea; ⁴General Surgery, Seoul National University Hospital, Seoul, Korea.
BackgroundDeceased donor kidneys with acute kidney injury (AKI) raise fear of poor graft outcomes to the transplant clinicians and consequently are often discarded. However, the…
2016 American Transplant Congress
Kidney Transplant Outcomes in Patients with CPRA Values >98% After Implementation of the New OPTN/UNOS Kidney Allocation System (KAS): A Single Center Study Update.
N. Kaur,¹ S. Goral,¹ J. Kearns,² P. Abt,³ A. Naji,³ P. Porrett,³ M. Levine,³ M. Kamoun.²
¹Renal, Electrolyte and Hypertension Division, University of Pennsylvania Medical Center, Philadelphia; ²Pathology and Laboratory Medicine, University of Pennsylvania Medical Center, Philadelphia; ³Surgery, University of Pennsylvania Medical Center, Philadelphia.
Background: Sensitized patients have had prolonged waiting times and greater incidence of death while on the waiting list. On December 4, 2014, UNOS/OPTN activated a…
2016 American Transplant Congress
Tipping the Scales: Liver Transplant Outcomes of the Super Obese.
R. Gedaly, J. Berger, X. Mei, F. Marti, L. Turcios, M. Shah.
Surgery, University of Kentucky, Lexington.
Objective: We aim to study outcomes in liver transplant recipients with BMI >50 using the UNOS database.Methods: We reviewed patients undergoing liver transplantation recorded in…
2016 American Transplant Congress
Intra-Operative Hepatic Arterial Flow Predicts Hepatic Artery Complications After Deceased Donor Liver Transplantation.
H. Fernandez, G. Testa, G. Klintmalm, P. Kim.
Baylor University, Dallas, TX.
IntroductionHepatic arterial flow (HAF) is important for post liver transplant outcomes. This study was conducted to determine the predictive value of measured intraoperative HAF on…
2016 American Transplant Congress
Renal Vein Thrombosis Incidence in 3976 Consecutive Kidney Transplants: Retrospective Analyses Focusing on Intraoperative Risk Factors.
H. Marinho Neto, B. Leslie, J. Neves Neto, J. Offerni, A. Pessoa, M. Almeida, M. Nogueira, S. Ximenes, W. Aguiar, H. Tedesco, J. Medina Pestana.
Kidney Hospital, São Paulo, Brazil.
INTRODUCTION: Although rare (incidence of 0,1 to 8.2%), renal vein thrombosis is a major cause o early graft loss. Here we try to identify perioperative…