ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Understanding the Initial Rise in Kidney Discard Rates Observed Post-KAS.

    D. Stewart,1 A. Kucheryavaya,1 R. Brown,1 D. Klassen,1 N. Turgeon,2 M. Aeder.3

    1UNOS, Richmond, VA; 2Emory Univ, Atlanta, GA; 3Univ Hosp Case Med Ctr, Cleveland, OH.

    Background: Kidney discard rates increased by 10% -- from 18.3% to 20.2% (p=0.001) -- during the first 7 months of KAS but returned to pre-KAS…
  • 2016 American Transplant Congress

    Investigating Posttransplant Allo-Donor Specific CD57+ Cells in Patients with Alemtuzumab Induction and Belatacept-Based Regimen.

    H. Xu, F. Feng, A. Kirk.

    Department of Surgery, Duke University, Durham, NC.

    Recent studies have showed correlation between CD4+CD57+PD1- cells and costimulation blockade resistant rejection (CoBRR) in patients treated with belatacept without depletional induction. We have recently…
  • 2016 American Transplant Congress

    Pulse Pressure and GFR Decay in Kidney Transplant Recipients.

    O. Sanchez, S. Reule, R. Spong, N. Issa, A. Kukla, A. Matas, H. Ibrahim.

    U of MN, Mpls.

    Single blood pressure values have commonly been used to assess the risk of allograft failure in kidney transplant recipients. In this analysis we prospectively evaluated…
  • 2016 American Transplant Congress

    A Pathway to Belatacept Monotherapy: Alemtuzumab, Belatacept and Rapamycin for Kidney Transplantation.

    A. Guasch,1 H. Xu,2 A. Mehta,1 A. Ghali,1 S. Mead,1 H. Gebel,1 R. Bray,1 C. Larsen,1 T. Pearson,1 A. Kirk.2

    1Emory Transplant Center, Atlanta, GA; 2Duke University, Durham, NC.

    Kidney transplantation remains limited by toxicities of calcineurin inhibitors (CNIs) and steroids. Belatacept is a less toxic CNI alternative delivered by monthly intravenous infusion, but…
  • 2016 American Transplant Congress

    IgG Dilutions, Subclasses, C1q, and IgM: Determining Relevant Testing for De Novo DSA and Outcome Prediction.

    M. Everly,1 L. Rebellato,2 C. Haisch,2 K. Briley,2 P. Bolin,2 S. Kendrick,3 C. Morgan,2 A. Maldonado,4 A. Nguyen,1 P. Terasaki.1

    1Terasaki Foundation Laboratory, Los Angeles; 2East Carolina University, Greenville, NC; 3Eastern Nephrology Associates, Greenville, NC; 4Vidant Medical Center, Greenville, NC.

    Numerous publications have shown secondary antibody testing of IgG (subclasses, C1q, etc) in de novo DSA (dnDSA) positive patients may have clinical relevance. Herein, we…
  • 2016 American Transplant Congress

    Nondirected Kidney Donation – Donating More Than a Kidney.

    C. Jacobs,1 J. Wiseman,1 D. Berglund,1 D. Larson,1 C. Garvey,1 M. Vogues,1 S. Rein,1 O. Sanchez,1 C. Radecki Breitkopf,2 H. Ibrahim,1 A. Matas.1

    1U of MN, Mpls; 2Mayo Clinic, Rochester.

    Little is known about donation-related out-of-pocket costs incurred by NDD. For NDD, we studied: resources used to cover these costs; level of stress due to…
  • 2016 American Transplant Congress

    Increased Access to Transplantation of Highly Sensitized Patients Facilitated by the New Kidney Allocation System.

    A. Colovai, M. Ajaimy, C. Savchik, S. Chan, P. Masiakos, J. Rocca, E. Akalin.

    Abdominal Transplant, Montefiore Medical Center, Bronx, NY.

    The purpose of our study was to evaluate the impact of the new kidney allocation system (KAS 2014) on the access to transplantation of HLA…
  • 2016 American Transplant Congress

    Molecular Assessment of Kidney Transplant Biopsies Performs Similarly in Medulla and Cortex.

    K. Madill-Thomsen,1 J. Reeve,1 G. Bohmig,2 F. Eskandary,2 P. Halloran.1,3

    1Alberta Transplant Applied Genomics Center, Edmonton, AB, Canada; 2Department of Nephrology and Dialysis, Medical University of Vienna, Vienna, Austria; 3Department of Medicine, Division of Nephrology and Transplant Immunology, University of Alberta, Edmonton, AB, Canada.

    Histologic assessment of kidney biopsies is usually unable to interpret medulla, but molecular changes associated with rejection likely occur in both medulla and cortex. Analysis…
  • 2016 American Transplant Congress

    Pre-Transplant Panel of Reactive T Cells (PRT) as an Independent Predictor of 2-Year Kidney Graft Function.

    I. Gandolfini,1 E. Crespo,2 M. Baweja,1 U. Maggiore,3 P. Cravedi,1 P. Heeger,1 O. Bestard.2

    1Icahn School of Medicine, New York, NY; 2Bellvitge University Hospital, Barcelona, Spain; 3University of Parma, Parma, Italy.

    Background: The ELISPOT PRT quantifies frequencies of IFN-g-producing effector/memory T cells reactive against a panel of allogenic stimulators. In contrast to the donor-reactive ELISPOT, it…
  • 2016 American Transplant Congress

    Global Kidney Exchange.

    M. Rees,1 T. Dunn,1 S. Rees,1 J. Rogers,1 L. Reece,1 A. Roth,2 C. Kuhr,1 O. Ekwenna,1 D. Fumo,1 K. Krawiec,3 S. Jain,1 C. Marsh,1 M. Tan,1 S. Paloyo.4

    1Alliance for Paired Kidney Donation, Perrysburg; 2Stanford University, Palo Alto; 3Duke University, Durham; 4Philippine General Hospital, Manila, Philippines.

    Introduction: Instead of thinking of the developing world as a place where there are desperate people who will sell their kidneys for money, we propose…
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