ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Preemptive CMV Prophylaxis in Renal Transplant Recipients Receiving Everolimus Immunosuppression Reduces Cytomegalovirus Infection.

    G. Spagnoletti, M. Salerno, V. Bianchi, N. Silvestrini, F. Apponi, J. Romagnoli.

    Surgery - Renal Transplant Unit, Università Cattolica del Sacro Cuore, Rome, Italy.

    Introduction.Aim of this study was to evaluate the efficacy and safety of preemptive prophylaxis of CMV infection in kidney transplant recipients (KTx) receiving polyclonal antibodies…
  • 2016 American Transplant Congress

    Adenovirus Infection in Kidney Transplant Recipients: Report of a Case Series.

    C. Simancas-Ruiz, L. Marino-Vazquez, A. Meraz-Muñoz, A. Nuñez-Abreu, R. Rivera-Marfil, N. Uribe-Uribe, J. Alberu, L. Morales-Buenrostro.

    Nephrology, Transplant and Pathology, National Institute of Medical Sciences and Nutrition SZ, México, DF, Mexico.

    Introduction: In kidney transplant recipients, the incidence of adenovirus infection is 4.1%, usually occur in the first three months after transplantation. Patients may have viral…
  • 2016 American Transplant Congress

    Detection of Endothelial Cell Specific Molecule-1 According to Allograft Status After Kidney Transplantation.

    J.-W. Seo, S.-Y. Kim, Y.-G. Kim, Y.-H. Jeong, Y.-H. Lee, J.-Y. Moon, T.-W. Lee, C.-G. Ihm, S.-H. Lee.

    Division of Nephrology, Department of Internal Medicine, College of Medicine, Kyung Hee University, Seoul, Republic of Korea.

    To investigate urine ESM-1(endothelial cell specific molecule-1) as well as plasma ESM-1 level from renal allograft recipients, we show whether there is the difference of…
  • 2016 American Transplant Congress

    Expansion of Anti-HLA Antibodies After Renal Transplantation and Prognosis in Those Which Fix C1q.

    P. Ruiz-Esteban,1 M. Gonzalez-Molina,1 A. Caballero,2 A. Torio,2 M. Leon,3 E. Palma,1 D. Burgos,1 M. Cabello,1 V. Lopez,1 M. Rodriguez,4 D. Hernandez.1

    1Nephrology, Regional University Hospital, IBIMA, University of Malaga, Malaga, Spain; 2Immunology, Regional University Hospital, IBIMA, University of Malaga, Malaga, Spain; 3Pathology, Regional University Hospital, IBIMA, University of Malaga, Malaga, Spain; 4Nephrology, Torrecardenas Hospital, Almeria, Spain.

    Introduction. Antibody-mediated rejection (ABMR) is the major cause of allograft failure. We studied the evolution and prognostic effect of pre-formed and de novo anti-HLA antibodies…
  • 2016 American Transplant Congress

    In Vitro and In Vivo Characterization of Human Hematopoietic Chimeric Cells – A Novel Approach for Tolerance Induction in Transplantation.

    M. Siemionow, E. Tfaily, M. Cyran, R. Gendek, M. Strojny, E. Szilagyi, J. Cwykiel.

    Department of Orthopaedics, University of Illinois at Chicago, Chicago, IL.

    Background: Cell-based therapies represent a new promising approach for tolerance induction in transplantation. One of the methods for immune response modulation in solid organ and…
  • 2016 American Transplant Congress

    Human Multipotent Mesenchymal Stromal Cells Improve Survival and Function of Pancreatic Islets by Cell-to-Cell Contact.

    E. Montanari,1 R. Meier,2 D. Bosco,1 R. Mahou,3 P. Morel,2 J. Seebach,4 C. Wandrey,3 C. Gonelle-Gispert,1 L. Bühler.2

    1University of Geneva, Geneva, Switzerland; 2Division of Digestive and Transplantation Surgery, University Hospitals of Geneva, Geneva, Switzerland; 3Institut d'Ingénierie Biologique et Institut des Sciences et Ingénierie Chimiques, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland; 4Division of Immunology and Allergy, University Hospitals of Geneva, Geneva, Switzerland.

    Background: MSC exhibit immunomodulatory and anti-inflammatory properties. Notably, MSC were shown to preserve human islet function and to prevent cytokine-induced apoptosis. Aim: To evaluate the…
  • 2016 American Transplant Congress

    Calcineurin Inhibitor (CNI) Nephrotoxicity Is Mediated by Defective Amp-Activated Protein Kinase (AMPK) Activation.

    A. Zmijewska, J. Chen, J. Zmijewski, R. Mannon.

    Medicine, UAB, Birmingham, AL.

    Background: CNIs are potent immunosuppressant therapies, but associated with nephrotoxicity manifested by interstitial fibrosis and progressive graft dysfunction. AMPK is a major sensor and regulator…
  • 2016 American Transplant Congress

    Three-Year Outcome After HSCT with Subsequent KT from the Same Haploidentical Donor without Immunosuppression.

    C. Schwarz,1 A. Lawitschka,2 G. Böhmig,3 E. Dauber,4 H. Greinix,5 N. Kozakowski,6 F. Mühlbacher,1 G. Berlakovich,1 T. Wekerle.7

    1Dept. of Surgery, Div. of Transplantation, Medeical University of Vienna, Vienna, Austria; 2St. Anna Children's Hospital, Vienna, Austria; 3Dept. of Internal Medicine, Division of Nephrology, Medical University of Vienna, Vienna, Austria; 4Dept. of Transfusion Medicine, Medical University of Vienna, Vienna, Austria; 5Dept of Internal Medicine, Div of Hematology, Medical University of Graz, Graz, Austria; 6Dept. of Clinical Pathology, Medical University of Vienna, Vienna, Austria; 7Section of Transplantation Immunology, Dept. of Surgery, Medical University of Vienna, Vienna, Austria.

    Allogeneic hematopoietic stem cell transplantation (HSCT) can lead to donor-specific tolerance. Patients reported in the literature that underwent kidney transplantation (KT) after a previous HSCT…
  • 2016 American Transplant Congress

    Assessing Vaccination Status in Transplant Candidates and Recipients: Current Status and Challenges to Successful Implementation.

    H. Leung, K. Cameron, B. Ho, M. Ison.

    Northwestern University Feinberg School of Medicine, Chicago, IL.

    Background: Vaccines are safety and efficacy of vaccines in transplant candidates and recipients. Several studies have demonstrated significant underutilization of vaccines which increases the risk…
  • 2016 American Transplant Congress

    Lipid Metabolism and Preservation of Discarded Steatotic Human Livers Using 24 Hours Ex-Vivo Normothermic Machine Perfusion.

    Q. Liu, A. Nassar, G. Iuppa, B. Soliman, L. Buccini, M. Blum, T. Okamoto, T. Uso, A. Bennett, W. Baldwin, K. Abu-Elmagd, J. Fung, C. Miller, C. Quintini.

    Cleveland Clinic, Cleveland, OH.

    One primary reason to discard donor livers after procurement is severe steatosis. The impact of normothermic machine perfusion (NMP) on lipid metabolism and preservation of…
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