ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Universal Stenting of Renal Transplants Associated with a Low Complication Rate When Quality Assurance Program Ensures Stent Removal.

    C. Yeast, J. Riley, C. Ashbaugh, G. Ross, M. Wakefield.

    Urology, University of Missouri, Columbia, MO.

    Introduction: The routine use of ureteral stents during renal transplantation remains controversial despite recent evidence that universal stenting decreases ureteric complications. Further, assurance of timely…
  • 2016 American Transplant Congress

    Outcome After Kidney Transplant (KTx) in Patients with Chronic Hypotension on Haemodialysis (HD).

    O. Manolitsi, N. Kessaris, J. Olsburgh, I. Loukopoulos.

    Kidney and Pancreas Transplant Unit, Surgical Department, Guy's and St Thomas'NHS Foundation Trust, London, United Kingdom.

    5% of the HD population have chronic hypotension ( hypotension in the absence of volume depletion, antihypertensive medication, heart failure or cortisol deficiency). The perioperative…
  • 2016 American Transplant Congress

    Down-Regulated of Circulating miR-29b, miR-185 and NR_073415.2 in Post-Transplanted Patients with Cytomegalovirus Infection May Serve as Novel Biomarkers for Early Diagnosis.

    A. Yang, W. Ju, Z. Guo, C. Wu, J. Lin, M. Chen, R. Deng, E. Chen, Y. Gao, X. Zhu, X. He.

    Organ Transplantation Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.

    Aims: Mortality of CMV infection in post-transplanted patients was quite high, which severely influencing the long-term survival of recipients. For giving them early treatment and…
  • 2016 American Transplant Congress

    Evaluation of the Impact of the Implementation of a Specialty Pharmacy Program in the Treatment of Hepatitis C (HCV).

    E. Aldag, T. Pedone, R. Pedersen, S. Besur, K. Safdar, A. Sahajpal.

    Aurora St Luke's Medical Center, Milwaukee, WI.

    Background: Current guidelines recommend newer therapies over previous interferon-based treatments. The creation of a specialty pharmacy program within our institution that provides managed care for…
  • 2016 American Transplant Congress

    Impact of Angiotensin II Type I Receptor Antibody Positivity in Highly-HLA Sensitized (HS) Patients Transplanted After Desensitization (DES).

    A. Vo,1 C. Boutsicaris,1 X. Zhang,2 N. Reinsmoen,2 J. Choi,1 S. Jordan.1

    1Kidney Transplant, Cedars-Sinai Medical Center, LA, CA; 2HLA Laboratory, Cedars-Sinai Medical Center, LA, CA.

    Introduction: Angiotensin II type I receptor antibody (AT1R Ab) is a target for non-HLA antibodies. AT1R ab exert direct effects on endothelial and vascular smooth…
  • 2016 American Transplant Congress

    Alloimmunity Through Non-HLA Epitopes in Kidney Transplantation.

    R. Reindl-Schwaighofer,1 A. Kainz,1 B. Cole,2 J. van Setten,2 K. Jelencsics,1 B. Keating,2 R. Oberbauer.1

    1Department of Nephrology, Medical University of Vienna, Vienna, Austria; 2Transplant Division, University of Pennsylvania, Philadelphia, PA.

    Introduction: An unexpected diversity in the human genome has been identified including more than 2,500 nonsynonymous single nucleotide polymorphisms (nsSNP) and up to 20 homozygous…
  • 2016 American Transplant Congress

    FGF and Wnt Signaling in Pancreatic Progenitor and Beta-Cell Growth.

    S. Afelik,1 N. Yonan,1 B. Pool,2 J. Jensen,2 J. Oberholzer.1

    1Surgery, Division of Transplantation, University of Illinois, Chicago, IL; 2Stem Cell Biology and Regenerative Medicine, Cleveland Clinic Foundation, Cleveland, OH.

    Beta-cell replacement therapy offersa cure for diabetes, but this is limited by the lack of readilyavailable supply of cells. Our goal is generate enough beta-cells…
  • 2016 American Transplant Congress

    Delaying the Induction of Mixed Chimerism Until Two Months After NHP Heart and Kidney Cotransplantation Results in Long Term Survival.

    K. Huh,1 M. Tonsho,1 P. Spencer,1 J. Paster,1 X. Wu,1 I. Hanekamp,1 T. Kawai,1,3 R. Smith,2 A. Cosimi,1 A. Dehnadi,1 G. Benichou,1 R. Colvin,1,2 J. Madsen.1,4

    1Center for Transplantation Sciences, Department of Surgery, Massachusetts General Hospital, Boston, MA; 2Department of Pathology, Massachusetts General Hospital, Boston, MA; 3Department of Surgery, Massachusetts General Hospital, Boston, MA; 4Division of Cardiac Surgery, Department of Surgery, Massachusetts General Hospital, Boston, MA.

    Background. We have previously achieved delayed tolerance in cynomologous recipients cotransplanted with heart and kidney allografts by treating recipients with standard triple drug immunosuppression for…
  • 2016 American Transplant Congress

    MiRNA-200b Inhibits Epithelial-Mesenchymal Transition in TGF-β1 Induced Human Bronchial Epithelial Cells.

    S. Ladak, C. Ward, S. Ali.

    Institute of Cellular Medicine, Newcastle University, Newcastle Upon Tyne, United Kingdom.

    The role of TGF-β1 in mediating extracellular matrix remodeling during the pathogenesis of lung fibrosis has been well defined. Dysregulated expression of miRNA is increasingly…
  • 2016 American Transplant Congress

    Trends in Aspergillus Infection After Liver Transplantation, 1988-2014.

    R. Al Masri, L. Jennings, S. Asrani, G. Klintmalm, C. Spak.

    Transplant Hepatology/Transplant Surgery/Infectious Disease, Baylor University Medical Center, Dallas, TX.

    Background: Invasive Aspergillosis is an important cause of morbidity and mortality in liver transplant recipients. Aspergillus may account for up to 25% of all fungal…
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