ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Crisis on the Waiting List for Children Listed in Low Volume Solid Organ Transplant Centers.

    A. Rana, E. Brewer, W. Winkelmayer, C. O'mahony, J. Goss.

    Department of Abdominal Transplantation, Baylor College of Medicine, Houston, TX.

    Purpose: In a recent analysis, we demonstrated that children listed in low volume liver transplant centers had poor waitlist survival and a depressed transplant rate…
  • 2016 American Transplant Congress

    Utilization of HCV-Positive Donors' Kidneys: Potential Benefits in the Era of Direct Acting Antiviral (DAA) Therapy.

    B. Amundsen,1 M. Sise,2 M. Lin,3 H. Deirawan,1 E. Heher,2 B. Kimball,1 J. Markmann,1 N. Elias.1

    1Massachusetts General Hospital, Boston, MA; 2Massachusetts General Hospital, Boston, MA; 3Brigham and Women's Hospital, Boston, MA.

    Organ shortage and expanding kidney waiting list fostered utilization of HCV positive donors' organs (HCVD+). HCVD+ kidneys have slightly worse long term outcomes compared with…
  • 2016 American Transplant Congress

    HO-1/SIRT1/p53 Axis Regulates Macrophage Activation and Attenuates Liver Ischemia-Reperfusion Injury in Mice.

    K. Nakamura,1 M. Zhang,2 B. Ke,1 S. Kageyama,1 R. Busuttil,1 J. Araujo,2 J. Kupiec-Weglinski.1

    1Surgery, Liver Transplant, University of California-Los Angeles, Los Angeles, CA; 2Medicine, Division of Cardiology, University of California-Los Angeles, Los Angeles, CA.

    Background/Aim: The mechanism by which macrophage heme oxygenase-1 (HO-1)-Sirtuin1 (SIRT1) signaling promotes resistance against inflammation response in liver ischemia-reperfusion injury (IRI) remains elusive. As tumor…
  • 2016 American Transplant Congress

    Thoracic Simulation Allocation Modeling (TSAM) of a 6-Tier Allocation Strategy.

    M. Colvin,1 M. Skeans,1 L. Robbins Callahan,2 L. Edwards,2 J. Zeglin,1 S. Silvestry,3 R. Davies,4 M. Farr,5 A. Israni,1 J. Rogers.6

    1SRTR, Minneapolis; 2UNOS, Richmond; 3Florida Hospital Transplant Inst, Orlando; 4Nemours/AI duPont Hosp for Children, Wilmington; 5Columbia Univ Medical Center, New York; 6Duke Univ, Durham.

    Heart allocation policy (OPTN policy 6) is in development. To stratify medical urgency, the Heart Subcommittee of the OPTN Thoracic Committee developed a 6-tier algorithm…
  • 2016 American Transplant Congress

    Are Prior Living Kidney Donors with ESRD Being Listed and Receiving Transplantation Priority in a Timely Manner?

    J. Wainright, A. Kucheryavaya, D. Klassen, D. Stewart.

    UNOS, Richmond, VA.

    BackgroundPrior living donors (PLDs) receive very high priority on the kidney (KI) waiting list (WL). Programs must submit requests for PLD priority to the UNOS…
  • 2016 American Transplant Congress

    Post-Transplant Monitoring of Donor-Specific Anti-HLA Antibodies and Their Characteristics Improves Risk Stratification of Kidney Allograft Loss.

    D. Viglietti,1 A. Loupy,2 C. Bentlejewski,3 C. Legendre,2 D. Glotz,1 A. Zeevi,3 C. Lefaucheur.1

    1Saint-Louis Hospital, Paris, France; 2Necker Hospital, Paris, France; 3University of Pittsburgh Medical Center, Pittsburgh.

    Circulating donor-specific anti-HLA antibodies (DSA) are associated with allograft failure in solid-organ transplantation. We investigated the pathogenic characteristics of DSA that may improve risk prediction…
  • 2016 American Transplant Congress

    Geographic Differences in Racial Disparity Reduction in Kidney Transplant Rates Before and After the New Kidney Allocation System.

    R. Patzer,1 T. Melanson,1 M. Basu,1 L. Plantinga,1 L. McPherson,1 S. Mohan,2 J. Gander,1 D. Howard,1 S. Pastan.1

    1Emory University, Atlanta; 2Columbia University, New York.

    Background: Prior to the new kidney allocation system (KAS) implemented 12/4/2014, significant African American (AA) vs. white racial disparities existed in access to kidney transplantation…
  • 2016 American Transplant Congress

    Black Ethnicity as a Risk Factor for Poor Kidney Allograft Outcomes Post-Transplantation.

    S. Tahir,1 F. Jackson-Spence,1 H. Gillott,1 F. Everson,2 J. Nath,2 A. Sharif.2

    1University of Birmingham, Birmingham, United Kingdom; 2Queen Elizabeth Hospital, Birmingham, United Kingdom.

    Introduction: Registry studies, largely from the United States, have consistently demonstrated inferior outcomes for black patients undergoing renal transplant. A recent Canadian publication has challenged…
  • 2016 American Transplant Congress

    Successful Treatment of Hepatitis C in Renal Transplant Recipients with Directly Acting Antiviral Agents.

    M. Lubetzky,1 S. Chun,1 A. Joelson,1 E. Akalin,1 P. Gaglio,2 G. DeBoccardo.1

    1Transplantation, Albert Einstein College of Medicine, Bronx, NY; 2Hepatology, Columbia Universtiy, New York, NY.

    Background: Hepatitis C infection (HCV) in kidney transplant (KTx) recipients has been shown to be a risk factor for decreased patient and allograft survival. With…
  • 2016 American Transplant Congress

    Evaluation of Scoring Systems Predicting Patient Survival at Time of Kidney Transplantation.

    O. Staeck, D. Khadzhynov, A. Kleinsteuber, L. Lehner, M. Duerr, K. Budde, F. Halleck.

    Nephrology, Charite, Berlin, Germany.

    Introduction:Estimating life expectancy in kidney transplant recipients (KTR) at time of transplantation is important to achieve the best functional match between patient and graft survival.…
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