2016 American Transplant Congress
Renal Outcome with Eculizumab in Patients with aHUS with Native and Transplanted Kidneys: Pooled Analysis of 100 Patients.
Purpose: aHUS often progresses to ESRD and requires transplant (tx). Eculiumab (ECU), a terminal complement inhibitor, inhibits TMA irrespective of tx status. We evaluated outcomes…2016 American Transplant Congress
Factors Associated with Acute Rejections in Kidney Transplant Recipients: Time for HLA-DR Matching in Elderly Recipients?
Nephrology, Charite Universitaetsmedizin, Berlin, Germany.
Background. Within the Eurotransplant Senior Allocation Program (ESP) HLA-matching is neglected,potentially causing inferior outcomes. There is a lack of data analysing the long-term immunologic outcomes…2016 American Transplant Congress
Significant Association of Vitamin-D Receptor (VDR) Gene Polymorphism and Incidence of De Novo DSA in Renal Transplantation.
Department of Gastroenrological and Transplant Surgery, Hiroshima University, Hiroshima, Japan.
Objective-Renal Transplantation (RT) is the optimal choice forend stage renal disease. Despite all advances in the development ofeffective immunosuppressive regimens in renal transplantation one of…2016 American Transplant Congress
The Live Donor Champion Program: A Novel Approach to Identying Live Kideny Donors.
Surgery, Johns Hopkins University, School of Medicine, Baltimore, MD.
Background: The Live Donor Champion (LDC) program is a clinical program offered to kidney waitlist candidates at our high volume transplant center. The six-month program…2016 American Transplant Congress
Implications of Subclinical Borderline Acute Cellular Rejection Detected in Protocol Biopsies on Graft Outcomes.
Background: The effects of subclinical borderline acute cellular rejection (BACR-defined as I1T1 per Banff criteria) detected in protocol biopsies (Bx) on subsequent graft function and…2016 American Transplant Congress
Removing Geographic and Financial Barriers for Directed Living Kidney Donations: Lessons from Kidney Paired Donation.
1Univ Hosp Case Med Ctr, Cleveland, OH; 2UNOS, Richmond, VA.
Living donor (LD) kidney (K) transplants (Tx), which peaked at 6647 in 2004 (42.5% of tx), decreased by 2014 to 5538 (32.4% of tx). Although…2016 American Transplant Congress
ABO Incompatible Living Related Kidney Transplantation: Results of a Matched-Pair Analysis with ABO Compatible Living Donation.
Background: Organ shortage has led to an increase in living related kidney transplantation of ABO compatible (ABOc) as well as ABO incompatible (ABOi) organs. Here…2016 American Transplant Congress
Age and Education Level Are Predictors of Patient Preferences for Educational Formats in ESRD Patients Undergoing Transplant Education.
Background: Health literacy impacts hospitalizations and mortality. ESRD patients have reduced health literacy due to a high proportion of lower educational background and socioeconomic resources.…2016 American Transplant Congress
Limited Efficacy of Bortezomib on Desensitization via Rapid Humoral Compensation in a Sensitized Rhesus Model.
1Surgery, Duke University, Durham; 2Surgery, Emory University, Atlanta.
Sensitized patients comprise a significant proportion (30%) of candidates on the waiting list for transplantation. With recent evidence that the presence of donor-specific antibodies (DSA)…2016 American Transplant Congress
Immunologic Basis for Immunocloaking.
1BREONICS Inc., Watervliet, NY; 2Plastic Surgery, University of Utrecht, Utrecht, Netherlands.
A novel organ-specific immunomodifying therapy referred to as immunocloaking (IC) provides protection from early allograft rejection without immunosuppressive drugs. The IC binds to the surfaces…
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