Am J Transplant, Volume 16, Suppl 3 Archives - Page 23 of 180 - ATC Abstracts

2016 American Transplant Congress
Evaluation of the Long-Term Outcomes with Everolimus After Calcineurin Inhibitor Withdrawal: 36M Results of the H2304 and PROTECT Extension Studies.
L. Fischer,^1,2 J. Fung,¹ H. Metselaar,¹ G. Kaiser,^1,2 P. Schemmer,² P. Neuhaus,² G. Dong,³ P. Lopez,⁴ P. Bernhardt,⁴ H. Schlitt.²
¹H2304 study group, Hamburg, Germany; ²PROTECT study group, Hamburg, Germany; ³Novartis Pharmaceuticals Corporation, East Hanover, NJ; ⁴Novartis Pharma AG, Basel, Switzerland.
Background: The H2304 and PROTECT studies demonstrated reduced nephrotoxicity with everolimus (EVR)-based calcineurin inhibitor (CNI; cyclosporine: CsA, tacrolimus: TAC)-free regimens at Month (M) 12. Here,…
2016 American Transplant Congress
Pregnancy Excludes Women from Successful Living Donor Transplantation.
P. Porrett,¹ B. Bromberger,² S. Hashmi,¹ A. Morrison,¹ D. Sawinski.³
¹Surgery, University of Pennsylvania, Philadelphia, PA; ²Surgery, Columbia University, New York, NY; ³Medicine, University of Pennsylvania, Philadelphia, PA.
INTRODUCTION Pregnancy-induced sensitization (PIS) is a barrier to the transplantation of women and contributes significantly to gender disparity in transplantation. We hypothesized that this barrier…
2016 American Transplant Congress
Donors with Isolated Anti-HBc (“HBcAb Only”) Antibodies: True Evidence for Past Infection or Laboratory Artifact? Toward a Simple Confirmatory Test for HBcAb.
Y. Chang,^1,3 C. Chinchilla-Reyes,² M. Koss,^1,2 M. Nowicki.^1,2
¹Mendez National Institute of Transplantation Foundation, Los Angeles, CA; ²Viracor-IBT Laboratories, Los Angeles, CA; ³Western University of Health Sciences, Pomona, CA.
Use of organs from donors positive for hepatitis B virus (HBV) markers may safely expand the donor pool. Recently the American Society of Transplantation expert…
2016 American Transplant Congress
Donor-Derived Monocytes Migrate to the Contralateral Lung and Cause Neutrophilia Following Single Lung Transplant.
S. Chiu, Z. Zheng, H. Sun, M. DeCamp, Jr, G. Budinger, H. Perlman, A. Misharin, A. Bharat.
Northwestern University, Chicago, IL.
Purpose: Deterioration of the native lung from lung injury occurs in the majority of patients following single lung transplant, but its pathogenesis remains unknown. Here,…
2016 American Transplant Congress
Effect of Adipose Tissue-Derived Mesenchymal Stem Cells in a Rat Model of Chronic Renal Allograft Rejection.
R. Pepineli, F. Silva, P. Gouveia, G. Tavora, S. Gomes, I. Noronha.
Renal Division, University of Sao Paulo, Sao Paulo, Brazil.
Adipose tissue-derived mesenchymal stem cells (ASC) may represent a new strategy to prevent allograft rejection after kidney transplantation due to its immunomodulatory properties. In the…
2016 American Transplant Congress
HLA Identical Renal Transplant Tolerance Using Donor Hematopoietic Stems Cells (DHSC): Role of Immunoregulation.
J. Leventhal,¹ J. Mathew,¹ D. Salomon,² S. Kurian,² J. Friedewald,¹ L. Gallon,¹ X. Huang,¹ A. Tambur,¹ Y. Kanwar,¹ J. Charette,¹ M. Abecassis,¹ J. Miller.¹
¹Surgery - Comprehensive Transplant Center, Northwestern University, Chicago, IL; ²The Scripps Research Institute, La Jolla, CA.
Purpose: Despite being a “perfect match”, HLA-identical kidney transplants (HLA-Id KTx) are rejected without sufficient immunosuppression (IS), and hence can also benefit from tolerance induction.…
2016 American Transplant Congress
Short-Term Post-Donation Renal Function in Living Kidney Donors.
L. Fahmy, A. Massie, A. Muzaale, S. Sandal, E. Chow, D. Segev.
JHU, Baltimore.
Previous single-center studies of post-donation estimated glomerular filtration rate (eGFR) in living kidney donors were limited by small sample size and lack of generalizability. The…
2016 American Transplant Congress
Utilization and Post-Transplant Outcomes Associated with Hepatitis C+ Donor Kidneys in the Advent of Direct-Acting Antivirals.
M. Bowring, L. Kucirka, A. Massie, X. Luo, M. Sulkowski, D. Segev, C. Durand.
JHU, Baltimore.
The introduction of interferon-free direct-acting antivirals(DAAs) in December 2013 dramatically improved outcomes for individuals with Hepatitis C. The impacts of these therapies on utilization and…
2016 American Transplant Congress
C1-Inhibitor in Acute Antibody-Mediated Rejection Non-Responsive to Conventional Therapy in Kidney Transplant Recipients: A Pilot Study.
C. Lefaucheur,¹ D. Viglietti,¹ C. Gosset,¹ A. Loupy,² A. Zeevi,³ D. Glotz.¹
¹Saint-Louis Hospital, Paris, France; ²Necker Hospital, Paris, France; ³University of Pittsburgh Medical Center, Pittsburgh.
The use of complement inhibitors in the treatment of acute antibody-mediated rejection (AMR) has not been thoroughly evaluated. We performed a prospective, single-arm, pilot study…
2016 American Transplant Congress
Improved Health Related Quality of Life Also in Older Recipients Following Kidney Transplantation.
K. Lønning,¹ K. Heldal,^2,3 T. Bernklev,^2,3 M. Andersen,^1,4 A. Hartmann,^1,3 N. Von der Lippe,³ A. Reisæter,¹ K. Midtvedt.¹
¹Department of Organ Transplantation, Oslo University Hospital, Oslo, Norway; ²Clinic of Internal Medicine, Telemark Hospital, Skien, Norway; ³Institute of Clinical Medicine, University of Oslo, Oslo, Norway; ⁴Department of Health Sciences, University of Oslo, Oslo, Norway.
Background: There is a lack of knowledge regarding elderly patients with end stage renal disease (ESRD) and health related quality of life (HRQOL) after KTX.…