Am J Transplant, Volume 16, Suppl 3 Archives - Page 23 of 180 - ATC Abstracts

2016 American Transplant Congress
Mycophenolic Acid Product Discontinuation Prior to Conception: Analysis of Pregnancies in Kidney Transplant Recipients.
S. Constantinescu,^1,2 L. Coscia,² D. Armenti,² M. Moritz.^2,3
¹Medicine, Temple University, Philadelphia, PA; ²Gift of Life Institute, National Transplantation Pregnancy Registry (NTPR), Philadelphia, PA; ³Surgery, Lehigh Valley Health Network, Allentown, PA.
Mycophenolic acid (MPA) products are considered teratogenic and transplant centers report discontinuing MPA in female kidney recipients anticipating pregnancy. Data were collected by the National…
2016 American Transplant Congress
B Cell Signature Profiling in Kidney Transplant Patients on Thymoglobulin.
A. Benitez,¹ T. Milford,² K. Torralba,³ K. Payne,² M. De Vera.¹
¹Transplantation Institute, Loma Linda University Health Care, Loma Linda, CA; ²Basic Science Division of Anatomy, Loma Linda University, Loma Linda, CA.
Purpose: B cell subsets could be used as biomarkers to modulate therapy regimens in kidney transplant patients. B cell subsets occur with varying proportions within…
2016 American Transplant Congress
Induction Therapy with Depleting Antibodies in Low Immunological Risk Renal Transplant Patients Treated with a Steroid Free Regimen – Comparison of Alemtuzumab vs. Antithymocyte Globulin.
N. Bossini,¹ S. Sandrini,¹ R. Tardanico,² F. Valerio,¹ G. Setti,¹ C. Salviani,¹ S. Possenti,¹ P. Foini,¹ E. Marta,¹ G. Cancarini.¹
¹Division and Chair of Nephrology, A.O "Spedali Civili" and University, Brescia, Italy; ²Division and Chair of II Laboratory of Pathology, A.O "Spedali Civili" and University, Brescia, Italy.
Induction therapy with depleting antibodies reduces rejection rate and potentially improves efficacy of steroid free regimens after renal transplantation.This prospective, single-centre, cohort study evaluated cumulative…
2016 American Transplant Congress
Resolution of Undefined Etiology of Respiratory Infections in Lung Transplant Patients with Unbiased Metagenomic Sequencing.
N. Mueller,¹ D. Lewandowska,² B. Ruehe,² P. Schreiber,¹ O. Zagordi,² F. Geissberger,² M. Schuurmans,³ M. Greiner,¹ A. Zbinden,² J. Boeni,² C. Benden,³ A. Trkola,² M. Huber.²
¹University Hospital Zurich, Division of Infectious Diseases, Zurich, Switzerland; ²University of Zurich, Institute of Medical Virology, Zurich, Switzerland; ³University Hospital Zurich, Division of Pulmonary Medicine, Zurich, Switzerland.
Study Purpose A high number of post-transplant infections with respiratory symptoms remain unresolved, despite routine testing for the common respiratory viruses. Using an open metagenomic…
2016 American Transplant Congress
Serelaxin Decreases the Severity of Cold Ischemia-Reperfusion Injury After Liver Transplantation in Mice.
S. Kageyama, K. Nakamura, R. Busuttil, J. Kupiec-Weglinski.
The Dumont-UCLA Transplantation Center, UCLA, Los Angeles, CA.
Background. Extended cold preservation contributes to ischemia-reperfusion injury (IRI), which impairs graft function and leads to poor clinical outcomes. Serelaxin (SER), a recombinant form of…
2016 American Transplant Congress
Prevalence of Polyreactive Innate-Like B Cells Among Graft-Infiltrating B Cells in Human Cardiac Allograft Vasculopathy.
D. Chatterjee,¹ C. Moore,² B. Gao,³ K. Clerkin,¹ S. See,¹ D. Shaked,¹ K. Rogers,¹ S. Nunez,¹ Y. Veras,¹ L. Addonizio,¹ M. Givertz,⁴ Y. Naka,¹ D. Mancini,¹ R. Vasilescu,⁵ C. Marboe,⁵ S. Restaino,¹ J. Madsen,² E. Zorn.¹
¹Medicine, Columbia University Medical Center, NY, NY; ²Massachusetts General Hospital Transplant Center, Boston; ³First Hospital of Jilin University, Changchun, China; ⁴Brigham and Women's Hospital, Boston; ⁵Pathology & Cell Biology, Columbia University Medical Center, NY.
Cardiac allograft vasculopathy (CAV) is a leading cause of death in long-term heart transplant survivors. Dense B cell infiltrates are common in heart transplants with…
2016 American Transplant Congress
Criteria for the Diagnosis of Microvascular Inflammation (MVI) in Kidney Transplant Biopsies (KTxBx).
J. Grande,¹ R. Leduc,² The DeKAF Study Group.
¹Dept. of Lab Medicine & Pathology, Mayo Clinic College of Medicine, Rochester, MN; ²Division of Biostatistics, U. Minnesota School of Public Health, Minneapolis, MN.
The presence of MVI (Banff glomerulitis "g" score and Banff peritubular capillary "ptc" score) in KTxBx, often related to antibody mediated rejection (AMR), is associated…
2016 American Transplant Congress
Impact of Machine Perfusion on Long-Term Kidney Transplant Outcomes.
S. Sandal,^1,2 X. Luo,² A. Massie,² M. Cantarovich,¹ D. Segev.²
¹MUHC, Montreal, Canada; ²JHU, Baltimore.
Machine perfusion (MP) has been shown to decrease DGF rates in kidney transplant (KT) recipients when compared with static cold storage (CS). However, there is…
2016 American Transplant Congress
Complement-Binding Donor-Specific Anti-HLA Antibodies Are Associated with Severe Kidney Allograft Arteriosclerosis.
A. Loupy,¹ D. Viglietti,² J. Duong Van Huyen,¹ D. Glotz,² C. Legendre,¹ A. Zeevi,³ C. Lefaucheur.²
¹Necker Hospital, Paris, France; ²Saint-Louis Hospital, Paris, France; ³University of Pittsburgh Medical Center, Pittsburgh.
The role of circulating donor-specific anti-HLA antibodies (DSA) in the development of accelerated arteriosclerosis have been recently reported in kidney transplant recipients. This study investigated…
2016 American Transplant Congress
An Economical and Effective Vaccination Program in Patients Transplanted for Hepatitis B Virus Related Liver Diseases: A Prospective Study.
W. Ju, A. Yang, Q. Ren, D. Wang, Z. Guo, Y. Ma, A. Hu, Q. Tai, X. Zhu, X. He.
Organ Transplantation Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
Aims: To prospectively investigate the efficacy and safety of procedural HBV vaccination in patients transplanted for HBV related liver diseases for prevention of hepatitis B…