ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Plasma Endothelial Microvesicle Counts Indicate Allograft Rejection Following Kidney Transplantation.

    D. Zecher,1 A. Cumpelik,2 B. Ruhland,1 B. Banas,1 H. Hopfer,3 M. Dickenmann,4 J. Schifferli.2

    1Nephrology, Regensburg University Hospital, Regensburg, Germany; 2Biomedicine, Basel University Hospital, Basel, Switzerland; 3Pathology, Basel University Hospital, Basel, Switzerland; 4Nephrology, Basel University Hospital, Basel, Switzerland.

    Background: The release of surface-derived microvesicles (MV) is a common phenomenon of cellular activation and occurs specifically as a consequence of terminal complement complex assembly…
  • 2016 American Transplant Congress

    Clinical Analysis of Patients with Hepatocellular Carcinoma Recurrence After Living-Donor Liver Transplantation.

    D. Kim, G. Na, T. Hong, Y. You.

    Surgery, Seoul St. Mary's Hospital, Catholic University, Seoul, Korea.

    Purpose: For living-donor liver transplantation (LDLT), there has been a tendency to accept extended criteria in comparison with deceased-donor liver transplantation (DDLT). However, HCC recurrence…
  • 2016 American Transplant Congress

    Outcomes of Ductoplasty in Right Lobe Living Donor Grafts with More Than One Bile Duct.

    S. Kapoor, V. Varma, B. Nath, V. Kumaran.

    Liver Transplantation & HPB Surgery, Kokilaben Dhirubhai Ambani Hospital & Medical Research Institute, Mumbai, Maharashtra, India.

    Background:Biliary complications remain the Achilles's heel of LDLT, especially in the setting of multiple ducts in the right lobe graft. Hilar plate glissonian sheath preservation…
  • 2016 American Transplant Congress

    Eculizumab for Chronic Antibody-Mediated Injury in Kidney Transplant Recipients: A Randomized-Controlled Trial.

    S. Kulkarni,1 N. Kirkiles-Smith,2 Y. Deng,3 R. Formica,4 M. Gilbert,5 V. Broeckner,6 L. Bow,1 J. Pober.2

    1Surgery, Yale University, New Haven, CT; 2Immunobiology, Yale University, New Haven, CT; 3Yale Center for Analytical Sciences, Yale School of Public Health, New Haven, CT; 4Medicine, Yale University, New Haven, CT; 5Pathology, Yale University, New Haven, CT; 6Histopathology, Univeristy of Cambridge, Cambridge, United Kingdom.

    Purpose: We hypothesize that de novo donor specific antibody (DSA) in kidney transplant patients cause endothelial cell injury that is dependent on complement and treatment…
  • 2016 American Transplant Congress

    Early Onset Hyperuricemia Is a Prognostic Marker for Kidney Allograft Dysfunction.

    M. Han,1 S. Yang,2 I. Jung,3 S.-K. Park,4 Y. Kim,5 D. Han,5 Y. Kim,1 S. Kim,6 J. Lee.7

    1Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea; 2Kidney Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea; 3Department of Surgery, Seoul National University Boramae Medical Center, Seoul, Republic of Korea; 4Department of Internal Medicine, Asan Medical Center and University of Ulsan College of Medicine, Seoul, Republic of Korea; 5Department of Surgery, Asan Medical Center and University of Ulsan College of Medicine, Seoul, Republic of Korea; 6Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea; 7Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Republic of Korea.

    Aim: It is not certain whether hyperuricemia is a true risk factor of kidney allograft failure. We investigated the association of hyperuricemia and graft outcome.Methods:…
  • 2016 American Transplant Congress

    Should Obese Patients Undergo Renal Transplantation? A Retrospective Analysis to Assess Whether Body Mass Index Can Affect Transplant Outcome.

    A. Mehta,1 A. Marriott,1 A. Ghazanfar.2

    1St. George's, University of London, London, United Kingdom; 2Renal Transplant Unit, St. George's Hospital, London, United Kingdom.

    This study aims to analyze our renal transplant recipient population in terms of perioperative complications (90 day) and graft survival (3 years) in relation to…
  • 2016 American Transplant Congress

    Association Between GFR Decline and Long Term Outcome in Renal Transplantation.

    A. Delay,1 O. Moranne,2 N. Maillard,1 E. Alamartine,1 C. Mariat.1

    1Nephrology Department, CHU, Saint Etienne, France; 2Nephrology Department, CHU, Nimes, France.

    In renal transplantation, GFR decline is strongly associated to graft failure and patient death and thus could be an interesting proxy for clinical research. GFR…
  • 2016 American Transplant Congress

    Chemoprevention of Cutaneous Squamous Cell Carcinoma in Renal Transplant Recipients: A Case-Controlled Analysis.

    R. Anand, R. Hung, S. Frame, K. Bramham, M. Wain, A. Cronin.

    Guy's & St Thomas' NHS Foundation Trust, London, United Kingdom.

    Organ transplant recipients are up to 200 times more likely to develop cutaneous squamous cell carcinoma (SCC) than age-matched general populations. Systemic retinoids, such as…
  • 2016 American Transplant Congress

    Donor Risk Index for Intestinal & Multi-Visceral Transplantation.

    G. Zeng,1 M. Chen,2 X. Zhao,3 D. Landsittel,2 H. Sogawa.4

    1Department of Pathology, The Thomas E Starzl Transplantation Institute, Pittsburgh, PA; 2Division of General Internal Medicine, Department of Medicine, University of Pittsburgh, School of Medicine, Pittsburgh, PA; 3Department of General Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, China; 4Multi-Organ Transplant & Hepatobiliary, Westchester Medical Center, Valhalla, NY.

    Background: The Donor Risk Index and the Kidney Donor Profile Index (KDPI) have been utilized for liver and kidney transplantation in clinical and research setting.…
  • 2016 American Transplant Congress

    Eomesodermin Expression by CD8+ Alloreactive T Cells in Human and Nonhuman Primate Allograft Recipients.

    A. Perez-Gutierrez, L. Lu, A. Zahorchak, Y. Ono, A. Thomson, M. Ezzelarab.

    Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA.

    Background:The transcription factor Eomesodermin (Eomes) is critical in the maintenance of antigen-specific memory T cells (Tmem). We have shown previously that prolonged kidney allograft survival…
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