ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    The Optimal Time Point for Steroid Withdrawal After Kidney Transplantation Is One Year After Engraftment.

    M. Haller,1 M. Kammer,1,2 A. Kainz,2 G. Heinze,1 R. Oberbauer.1,2

    1Center for Medical Statistics, Informatics and Intelligent Systems (CeMSIIS), Medical University of Vienna, Vienna, Austria; 2Department of Medicine, Medical University of Vienna, Vienna, Austria.

    The optimal time of steroid withdrawal after kidney transplantation remains elusive, since RCTs can evaluate one predefined time point. Thus we analyzed all first kidney…
  • 2016 American Transplant Congress

    Impact of Delayed Graft Function Varies by Demographic and Clinical Characteristics in Deceased Donor Kidney Transplantation.

    C. Liao, A. Massie, S. Bae, A. Muzaale, D. Segev.

    JHU, Baltimore.

    Single-center studies have suggested potential differences in the impact of DGF by recipients' biological susceptibility, quality of allograft, and immune compatibility. The goal of this…
  • 2016 American Transplant Congress

    Association of Neighborhood Poverty and Living Donor Kidney Transplant Rates by Donor Relationship to Recipient.

    G. Vranic, A. Nishio Lucar, D. Keith.

    Medicine, University of Virginia, Charlottesville, VA.

    Background: Living donor (LD) kidney transplant is associated with increased access to transplant and improved patient and allograft outcomes. Despite the known benefits, LD rates…
  • 2016 American Transplant Congress

    Is C3d-fixing Donor Specific HLA Antibody Detection Really Necessary?

    P. Malvezzi,1 M. Villemaire,1 A. Bourdin,2 T. Jouve,1 R. Tetaz,1 B. Janbon,1 N. Terrier,3 D. Masson.2

    1Service de Néphrologie, Grenoble University Hospital, Grenoble, France; 2Laboratoire d'Histocompatibilité, EFS, Grenoble, France; 3Service d'Urologie, Grenoble University Hospital, Grenoble, France.

    Introduction: Chronic antibody–mediated rejection is the main cause of late kidney graft loss. The identification of donor-specific antibodies (DSA) in the serum is one of…
  • 2016 American Transplant Congress

    Malignancies Contribute to Presensitization with Alloreactive T-Cells in Kidney Transplant Recipients.

    T. Schachtner,1,2 M. Stein,2 P. Reinke.1,2

    1Nephrology and Internal Intensive Care, Charite Campus Virchow Clinic, Berlin, Germany; 2Berlin-Brandenburg Center for Regenerative Therapies, Charite Campus Virchow Clinic, Berlin, Germany.

    Alloreactive T-cells have been suggested to impact allograft outcome due to a higher incidence of acute rejection in the initial period after kidney transplantation. Knowledge…
  • 2016 American Transplant Congress

    Human B Cell Cytokines Predict Renal Allograft Rejection and Early Transplant Outcomes.

    A. Cherukuri, R. Mehta, S. Ogunde, S. Hariharan, D. Rothstein.

    UPMC, Pittsburgh.

    In renal transplantation, non-invasive biomarkers that are predictive and allow for early intervention are limited. Here we report findings from a prospective longitudinal study of…
  • 2016 American Transplant Congress

    Accumulation of Highly Sensitized Patients in a KPD Registry.

    S. Stepkowski, B. Mierzejewska, D. Bekbolsynow, M. Rees.

    University of Toledo, Toledo, OH.

    Objectives: We analyzed sensitization against HLA among patients in a kidney paired donation (KPD) registry. In particular, three groups of patients were included: 1) all…
  • 2016 American Transplant Congress

    Prediction of Patient Survival After Kidney Transplantation: Construction, Validation and Evaluation of Decision Models Using Data Mining Approaches.

    I. Scheffner,1 K. Hua,2 D. Simovici,2 T. Abeling,1 H. Haller,1 W. Gwinner.1

    1Nephrology, Hannover Medical School, Hannover, Germany; 2Computer Science, University of Massachusetts, Boston.

    Understanding the risk factors that predispose to death is important in order to deliver the most appropriate therapy to patients (pts) with kidney transplantation (Tx).…
  • 2016 American Transplant Congress

    ER Stress and Loss of GRP78 Expression Provides a Link Between Renal Ischemia/Reperfusion Injury and the Urinary Metabolome.

    C. van Kooten,1 T. Pacchiarotta,2 P. van der Pol,1 J. de Fijter,1 N. Schlagwein,1 D. van Gijlswijk,1 O. Mayboroda.2

    1Nephrology, Leiden University Medical Center, Leiden, Netherlands; 2Centre for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, Netherlands.

    Ischemia/reperfusion injury (IRI) profoundly impacts graft survival following kidney transplantation. Epithelial injury is one of the earliest histological alterations of IRI and is especially observed…
  • 2016 American Transplant Congress

    The Role of B Cells in Liver Transplant Tolerance.

    M. Morita,2 G. Enyindah-Asonye,1 N. Gupta,1 J. Fung,2 S. Qian,1,2 L. Lu.1,2

    1Immunology, LernerResearch Institute, Cleveland Clinic, Cleveland, OH; 2General Surgery, Transplant Center, Digestive Disease Institute, Cleveland Clinic, Cleveland, OH.

    Scarcely one would argue that donor-specific B cells and antibodies contribute to rejection of transplants. However, studies published in the past few years have provided…
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