Am J Transplant, Volume 16, Suppl 3 Archives - Page 2 of 180 - ATC Abstracts

2016 American Transplant Congress
Survival Benefit of High-KDPI Kidneys Among Obese Transplant Candidates.
M. Bowring, A. Massie, X. Luo, D. Segev.
JHU, Baltimore.
Obese patients have less access to kidney transplantation; use of high-KDPI kidneys could help expand access in this population, but the cumulative effect of obesity…
2016 American Transplant Congress
VO_2peak Outperforms Troponin T for Risk Prediction of Cardiovascular Disease and All-Cause Mortality in Patients with End Stage Renal Disease Being Evaluated for Kidney Transplant.
H. Chakkera,¹ C. Lee,² J. Dickinson,^1,2 B. Kaplan,^1,2 I. Qaqish,¹ S. Behmen,¹ R. Heilman,¹ H. Khamash,¹ J. Huskey,¹ S. Nair,¹ R. Scott,¹ D. Steidley,¹ M. Temkit,¹ S. Angadi.^1,2
¹Mayo Clinic, Arizona; ²Arizona State University, AZ.
Background: Cardiovascular disease (CVD) is a major health care concern in end-stage renal disease (ESRD). Peak oxygen uptake (VO2peak) is a strong predictor of CVD…
2016 American Transplant Congress
Adding Anti-Inflammatory Agents During Normothermic Ex-Vivo Liver Perfusion Improves the Preservation of Pig Liver Grafts Before Transplantation.
N. Goldaracena, E. Juan, K. Moritz, V. Spetzler, A. Barbas, D. Grant, M. Selzner.
Multi Organ Transplant Program, Toronto General Hospital, Toronto, Canada.
Introduction: Normothermic ex vivo liver perfusion (NEVLP) improves graft preservation by avoiding cold ischemic injury. We investigated if protective effects of NEVLP can be further…
2016 American Transplant Congress
Interaction Between Kidney Tissue Proteome and Humoral Immunity in Antibody Mediated Rejection.
A. Konvalinka,¹ A. Chruscinski,² S. Kim,¹ K. Tinckam,¹ I. Jurisica,³ R. John.⁴
¹Medicine/Division of Nephrology, Toronto General Hospital, Toronto, ON, Canada; ²Medicine/Division of Cardiology, Toronto General Hospital, Toronto, ON, Canada; ³Medical Biophysics and Computational Science, University of Toronto, Toronto, ON, Canada; ⁴Pathology, Toronto General Hospital, Toronto, ON, Canada.
PURPOSE: Antibody-mediated rejection (AMR) is caused by antibodies against human leukocyte antigens (HLA) on graft endothelium, and non-HLA antibodies that target endothelial and epithelial proteins.…
2016 American Transplant Congress
Resveratrol Effectively Suppress Th17 Associated Allo-Immune Responses by the Modulation of AMPK/mTOR Pathway.
B. Chung, K. Doh, J.-W. Min, K. Kim, B.-M. Kim, M.-L. Cho, C. Yang.
Department of Internal Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea.
The aim of this study is to investigate the effect of resveratrol on Th17 allo-immune responses under tacrolimus (Tac)-based immune suppression. First, we investigated the…
2016 American Transplant Congress
HLA Antibody Clonality and Epitopes Dictate Complement Activation.
K. Thomas,¹ N. Valenzuela,¹ A. Mulder,² E. Reed.¹
¹Pathology and Laboratory Medicine, UCLA, Los Angeles, CA; ²Leiden University Medical Center, Leiden, Netherlands.
Background: Alloimmunization results in production of polyclonal donor specific antibodies (DSA) against human leukocyte antigens (HLA), which mediate endothelial cell activation, leukocyte recruitment, and complement…
2016 American Transplant Congress
Concordance Between Pancreatic Rejection and Kidney Rejection and Kidney Survival in Simultaneous Pancreas Kidney Transplantation.
I. Moinuddin, T. Taber, M. Yaqub, D. Mishler, O. Adebiyi, J. Chen, M. Goble, J. Powelson, J. Fridell, A. Sharfuddin.
Transplant Nephrology, Indiana University, Indianapolis, IN.
Purpose: It is not known whether pancreas rejection is associated with increased kidney rejection. Also, it is not known whether pancreas survival affects kidney and…
2016 American Transplant Congress
Validation of SUITO Index and C-Peptide/Glucose Creatinine Ratio as Convenient Tools for the Evaluation of the Short and Long-Term Islet Allograft Function.
J. Gołębiewska,¹ J. Solomina,² S. Matosz,² C. Thomas,³ L. Schenck,² K. Golab,² W. Chon,³ S. Ramachandran,² M. Tibudan,² A. Dębska-ŚLizień,¹ B. Rutkowski,¹ P. Witkowski.²
¹Department of Nephrology, Transplantology and Internal Medicine, Medical University of Gdańsk, Gdańsk, Poland; ²Department of Surgery, University of Chicago, Chicago, IL; ³Department of Medicine, University of Chicago, Chicago, IL.
Background: Mixed Meal Tolerance Test (MMTT) together with the beta-score are standard tools to evaluate beta-cell function after islet transplantation but utilization of the test…
2016 American Transplant Congress
The In Vivo Non-Invasive Long-Term Functional Assessment of Neuronal Regeneration in Vascularized Composite Allotransplantation.
C.-J. Wen,^1,2 C.-H. Lin,¹ S.-L. Peng,^3,4 F.-N. Wang,³ L.-Y. Huang,³ H.-Y. Cheng,¹ H.-H. Hsu,¹ X.-T. Huang,¹ C.-H. Lin,¹ F.-C. Wei.¹
¹Center for Vascularized Composite Allotransplantation, Chang Gung Medical Foundation, Taoyuan, Taiwan; ²Department of Medicine, Chang Gung University, Taoyuan, Taiwan; ³Department of Biomedical Engineering and Environmental Sciences, Tsing Hua University, Hsinchu, Taiwan; ⁴Biomedical Imaging and Radiological Science, China Medical University, Taichung, Taiwan.
The neuronal regeneration is a key issue of vascularized composite allotransplantation (VCA).As for the generally used functional observations, behavior testing or invasive functional inspection (e.g.…
2016 American Transplant Congress
A2 Kidneys into B Recipients: Is Postoperative Anti-A1 Titer Monitoring Useful?
A. DeMers, R. Forbes, D. Moore, K. Smith, D. Shaffer.
Kidney and Pancreas Transplantation, Vanderbilt University Medical Center, Nashville, TN.
Background: Since the introduction of the new Kidney Allocation System in December 2014, our center implemented a protocol for transplanting A2 kidneys into B recipients…