2016 American Transplant Congress
Accumulation of Highly Sensitized Patients in a KPD Registry.
University of Toledo, Toledo, OH.
Objectives: We analyzed sensitization against HLA among patients in a kidney paired donation (KPD) registry. In particular, three groups of patients were included: 1) all…2016 American Transplant Congress
Prediction of Patient Survival After Kidney Transplantation: Construction, Validation and Evaluation of Decision Models Using Data Mining Approaches.
Understanding the risk factors that predispose to death is important in order to deliver the most appropriate therapy to patients (pts) with kidney transplantation (Tx).…2016 American Transplant Congress
ER Stress and Loss of GRP78 Expression Provides a Link Between Renal Ischemia/Reperfusion Injury and the Urinary Metabolome.
Ischemia/reperfusion injury (IRI) profoundly impacts graft survival following kidney transplantation. Epithelial injury is one of the earliest histological alterations of IRI and is especially observed…2016 American Transplant Congress
The Role of B Cells in Liver Transplant Tolerance.
Scarcely one would argue that donor-specific B cells and antibodies contribute to rejection of transplants. However, studies published in the past few years have provided…2016 American Transplant Congress
Learning from Cancer: Using D-Lactate for Therapeutic Immunosuppression.
Accumulation of lactic acid in the tumor microenvironment contributes to local immunosuppressive conditions that weaken anti-tumor immunity. Lactic acid exists as L- and D- optical…2016 American Transplant Congress
Kidney Allotransplantation Induces the Differentiation of Antigen-Experienced CD8 T Cells with Enhanced Metabolic Profiles.
Background. Naïve and memory CD8 T cells have been shown to exhibit different metabolic profiles, especially upon antigen stimulation. However, it is unknown whether the…2016 American Transplant Congress
Continuous Glucose Monitoring in the First 6 Weeks After Transplantation in Pancreas Transplant Recipients.
Introduction The maturation of Continuous glucose monitoring (CGM) technology enables accurate characterization of daily glucose control. We investigated glucose control using CGM in the first…2016 American Transplant Congress
Duodenal Graft Complications After Pancreas Transplant: Evolving Management.
Introduction Pancreas transplantation is an established treatment for insulin-dependent-diabetes-mellitus with renal failure. However, complications relating to the transplant duodenum remain a significant cause of morbidity…2016 American Transplant Congress
Peritransplant Costimulation Blockade Combined with a Short-Course of Rapamycin Prevents Rejection of Vascularized Composite Allografts.
[Background] Reconstructive transplantation represents a valid therapeutic option after devastating tissue loss. Routine clinical application, however, is hampered by the toxicity of long-term maintenance immunosuppression.…2016 American Transplant Congress
Survey Results Show Strong Support for Allowing Patients Undergoing Desensitization to Keep Their Pre-Desensitization CPRA Allocation Priority.
1UNOS, Richmond; 2Emory Univ Hosp, Atlanta; 3Stanford Univ, Palo Alto.
Background: On the waitlist, highly sensitized kidney (KI) candidates who undergo desensitization (DS) lose allocation priority associated with pre-DS CPRA value if some unacceptable antigens…
American Transplant Congress abstracts