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  • 2016 American Transplant Congress

    The Role of Obesity in Survival Outcomes of Liver Transplant Recipients with High MELD Score.

    S.-H. Chang,1 N. Carlsson,1 X. Liu,2 J. Wellen,3 J. Hagopian,4 T. Horwedel,4 T. Alhamad.5

    1Division of Public Health Sciences, Department of Surgery, Washington University in St. Louis, St. Louis; 2Division of Biostatistics, Washington University in St. Louis, St. Louis; 3Department of Surgery, Washington University in St. Louis, St. Louis; 4Department of Pharmacy, Barnes Jewish Hospital, St. Louis; 5Renal Division, Washington University, St. Louis.

    Background:Obesity has become an epidemic in the United States. More than one third of adults are obese, defined as having body mass index (BMI) greater…
  • 2016 American Transplant Congress

    Liver Graft Steatosis Associates with an Increase of Circulating Immune Response Chemokines.

    R. Gehrau, V. Mas, A. Sharma, V. Bontha, D. Maluf.

    University of Virginia, Charlottesville.

    Background: Liver graft steatosis, especially macrosteatosis induces severe graft injury post-liver transplantation (LT) by activating cell-mediated immunity and inflammation. This study aimed to determine differential…
  • 2016 American Transplant Congress

    The Role of Palliative Care in the Thoracic Transplant Multidisciplinary Care Team: Barriers and Benefits.

    A. Manfredi,1 C. Toevs.2

    1Loyola University Medical Center, Maywood, IL; 2Terre Haute Regional Hospital, Terre Haute, IN.

    PURPOSE: Patients under consideration for or who have undergone lung and heart transplantation experience many symptoms, including dyspnea, anxiety, pain and caregiver burden. Integration of…
  • 2016 American Transplant Congress

    Patients Treated with Belatacept Show Low Levels of APRIL and HLA Antibodies.

    M. Rial,1 N. Ambrosi,2 F. Caro,2 D. Curcio,1 J. Salaberry,2 O. Guardia,1 A. Dotta,1 D. Guerrieri,2 K. Padros,3 E. Chuluyan,2 D. Casadei.

    1Instituto de Nefrología, Nephrology, Buenos Aires, Argentina; 2CEFYBO, Facultad de Medicina, UBA-CONICET, Buenos Aires, Argentina; 3PRICAI, Fundación Favaloro, Buenos Aires, Argentina.

    Belatacept, a fusión protein that blocks the B7-CD28 costimulation pathway, decreases the level of antibodies in non-human primates and murine models but, few studies have…
  • 2016 American Transplant Congress

    Deceased Donor Kidney Transplantation in the Setting of Positive Donor-Specific Antibodies.

    B. Orandi,1 J. Montgomery,2 E. Kraus,1 D. Segev,1 R. Montgomery,1 N. Alachkar.1

    1Johns Hopkins University, Baltimore; 2University of Michigan, Ann Arbor.

    Recent changes to the kidney allocation system favor highly sensitized transplant candidates, resulting in these patients receiving more offers for deceased donor (DD) kidneys. Despite…
  • 2016 American Transplant Congress

    Clinical Factors That Determine the More Appropriate Induction Agent: ATG versus IL-2 Receptor Antagonists.

    S. Bae, A. Massie, S. DiBrito, X. Luo, L. Kucirka, F. Al Ammary, D. Segev.

    Johns Hopkins, Baltimore, MD.

    Antithymocyte globulin (ATG) is recommended over IL-2 receptor antagonist (IL2) in high-risk recipients for induction immunosuppression. However, “high-risk” status has not been defined in an…
  • 2016 American Transplant Congress

    Outcomes in Obese Renal Transplant Recipients Using High versus Low-Dose Thymoglobulin.

    N. Jasiak,1 C. Stromayer,1 J. Thielke,1 J. Chen,2 J. Chen,1 B. Talon,1 R. Rubin-Tobar,1 E. Benedetti,2 P. West-Thielke.1,2

    1Pharmacy, University of Illinois, Chicago; 2Transplant Surgery, University of Illinois, Chicago, IL.

    Background: Dosing of rabbit anti-thymocyte globulin (rATG) induction in renal transplant recipients is highly variable by transplant center. Optimizing rATG dose becomes extremely important for…
  • 2016 American Transplant Congress

    Prospective Randomized Controlled Study Evaluating the Relationship Between Electronic Adherence Data and Tacrolimus Concentration Data.

    B. Kane,1 M. Lockwood,1 L. Potter,1 L. Lourenco,1 A. Bodzin,1 D. Covington,2 K. Mayer,3 J. Millis.1

    1University of Chicago Transplant Center, University of Chicago, Chicago, IL; 2Clinical Research, Innovation Clinical Research, LLC, Tucson, AZ; 3R&D, SIMpill, LLC, Madison, WI.

    Purpose: The SIMpill® Medication Adherence System (MAS) is being evaluated in transplant recipients in a prospective 3-year study. The MAS captures patient medication adherence data…
  • 2016 American Transplant Congress

    Liver Graft Rejuvenation Prior to Transplantation: A Bench-to-Bedside Approach.

    A. Zarrinpar,1 B. Ke,1 H. Ji,1 E. Reed,2 R. Busuttil,1 J. Kupiec-Weglinski.1

    1Surgery, Dumont-UCLA Translant Center, Los Angeles, CA; 2Pathology, UCLA, Los Angeles, CA.

    To address the shortage of organs for transplantation many use “marginal” livers, which are particularly susceptible to ischemia-reperfusion injury (IRI). We have taken a two-pronged…
  • 2016 American Transplant Congress

    Ex Vivo Perfusion of Porcine Forelimbs to Prolong Allowable Ischemia Time.

    N. Krezdorn,1 M. Kueckelhaus,2 A. Dermietzel,2 M. Alhefzi,1 M. Aycart,1 S. Fischer,3 T.-S. Win,1 H. Kiwanuka,1 E. Bueno,1 B. Pomahac.1

    1Department of Surgery, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston; 2Department of Plastic Surgery, Burn Center, Sarcoma Reference Center, BG University Hospital Bergmannsheil, Bochum, Germany; 3Department of Hand, Plastic and Reconstructive Surgery, Burn Trauma Center, BG Trauma Center Ludwigshafen, Heidelberg, Germany.

    PurposeSuccessful replantation in patients suffering from traumatic amputation of one or more extremities is limited by the muscle ischemia time of 4-6h, which also holds…
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