Am J Transplant, Volume 16, Suppl 3 Archives - Page 175 of 180 - ATC Abstracts

2016 American Transplant Congress
Compensating Live Kidney Donors: The Views of United States Voters.
J. Fisher,¹ T. Peters,² R. Gish,³ R. Howard.⁴
¹Surgery, Scripps Center for Organ Transplantation, La Jolla, CA; ²Surgery, University of Florida, Jacksonville, FL; ³Medicine, Stanford University Medical Center, Stanford, CA; ⁴Surgery, LifeQuest Organ Recovery Services, Gainesville, FL.
Purpose: An increasing number of U.S. patients die waiting for a kidney transplant. Financial compensation of living donors is one possible remedy for the organ…
2016 American Transplant Congress
The Heterogenous Genomic Landscape of Unresectable Hepatoblastoma Requiring Liver Transplantation: Prognostic Implications.
M. Ningappa, B. Higgs, S. Ranganathan, C. Ashokkumar, R. Sindhi.
Surgery, Children's Hospital of Pittsburgh of UPMC and University of Pittsburgh, Pittsburgh, PA.
Background: Hepatoblastoma, the most common pediatric liver malignancy, is cured by chemotherapy and surgical resection. Locally invasive/multifocal tumors require liver transplantation (LTx). A unique tumor…
2016 American Transplant Congress
The Effect of Maternal Graft in Early Acute Cellular Rejection After Pediatric Living Donor Liver Transplantation.
Y. Noguchi,¹ T. Ueno,¹ K. Bessho,² Y. Takama,¹ H. Yamanaka,¹ N. Tanaka,¹ Y. Tazuke,¹ H. Okuyama.¹
¹Pediatric Surgery, Osaka University, Suita, Osaka, Japan; ²Pediatrics, Osaka University, Suita, Osaka, Japan.
Objectives: It has been reported that the living donor liver transplantation (LDLT) in which the patients received a maternal graft could be more successful compared…
2016 American Transplant Congress
Simultaneous Pancreas/Kidney Transplantation Increases the Risk of Late-Onset BKV-Associated Nephropathy.
T. Schachtner,^1,2 M. Zaks,¹ A. Kahl,¹ P. Reinke.^1,2
¹Nephrology and Internal Intensive Care, Charite Campus Virchow Clinic, Berlin, Germany; ²Berlin-Brandenburg Center for Regenerative Therapies, Charite Campus Virchow Clinic, Berlin, Germany.
Infections have increased in simultaneous pancreas/kidney transplant recipients (SPKTRs) with BKV-associated nephropathy (BKVN) being the most important infectious cause of allograft loss. Comparisons of BKVN…
2016 American Transplant Congress
Tacrolimus Precision Medicine: Antibiotics Increase Intra-Patient Variability in Tacrolimus Trough Concentrations in Kidney Transplant Recipients.
Y. Zheng, J. Lee, A. Masand, D. Dadhania, M. Thangamani, M. Suthanthiran.
Medicine/Nephrology and Hyeprtension, Weill Cornell Medical College, New York, NY.
BACKGROUND. The gut microbiome impacts drug absorption, metabolism, and distribution and was recently shown to be associated with tacrolimus dosing requirements. Since antibiotics can alter…
2016 American Transplant Congress
Urgent Kidney Transplantation as Successful Treatment of Calciphylaxis in Three Patients with End-Stage Kidney Failure.
E. Nordheim,¹ D. Dahle,¹ I. Syse,¹ A. Åsberg,^1,2 A. Reisæter,¹ H. Holdaas,¹ T. Jenssen,^1,3 A. Hartmann.^1,4
¹Transplantation Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway; ²Shool of Pharmacy, University of Oslo, Oslo, Norway; ³Kidney, Arctic University of Tromsø, Tromsø, Norway; ⁴Institute of Clinical Medicine, Medical Faculty, University of Oslo, Oslo, Norway.
Background: Calciphylaxis often referred to as calcific uremic arteriolopathy (CUA) is a rare and serious complication with limited treatment options. Kidney transplantation restores kidney function…
2016 American Transplant Congress
Effect of Inflammation on Concentration of Intracellular Tacrolimus.
E. Bae,¹ S. Yang,² S. Han,¹ J.-Y. Park,¹ H. Lee,¹ Y. Kim.¹
¹Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea; ²Kidney Research Institute, Seoul National University, Seoul, Republic of Korea.
Background: The use of calcineurin inhibitors improved the outcome for transplant recipients. However, acute rejection (AR) and infection remained still an unsolved problem. We evaluated…
2016 American Transplant Congress
Tacrolimus Levels in Patients Treated with Direct Acting Antivirals Post-Transplant.
J. Wiegel, T. Egbuka.
Pharmacy, Oregon Health & Science University, Portland, OR.
Purpose: To determine if treatment of recurrent hepatitis C virus (HCV) post-liver transplant with the direct-acting antivirals (DAAs) sofosbuvir, simeprevir, and ledipasvir (in combination and/or…
2016 American Transplant Congress
Initial Experience with the Bacterial Enzyme IdeS® (IgG Endopeptidase) for Desensitization of Highly-HLA Sensitized (HS) Patients.
S. Jordan,¹ J. Choi,¹ X. Zhang,¹ M. Haas,² A. Peng,¹ J. Kahwaji,¹ R. Villicana,¹ A. Vo.¹
¹Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA; ²Pathology, Cedars-Sinai Medical Center, Los Angeles, CA.
Introduction: The IgG degrading enzyme derived from Streptococcus pyogenes (IdeS®) is a 35k-Da cysteine protease that cleaves human IgG molecules at the lower hinge region…
2016 American Transplant Congress
Porcine Islets Engineered to Display SA-FasL Protein on Their Surface Induce Tolerance in Mice Following Transplantation into the Liver or Under the Kidney Capsule.
H. Zhao,¹ K. Woodward,¹ H. Shirwan,¹ M. Graham,² B. Hering,² E. Yolcu.¹
¹Institute for Cellular Therapeutics and Department of Microbiology and Immunology, University of Louisville, Louisville, KY; ²Schulze Diabetes Institute and Department of Surgery, University of Minnesota, Minneapolis, MN.
Introduction: We have recently demonstrated that allogeneic islets engineered to transiently display on their surface a novel form of FasL protein chimeric with streptavidin (SA-FasL)…