ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Acute Kidney Injury and Chronic Kidney Disease in Donation After Circulatory Death Liver Transplantation: UK Single Centre Study.

    I. Umbro,1,2 F. Tinti,1,2 F. Evison,3 A. Sharif,4 B. Gunson,5 A. Mitterhofer,2 J. Ferguson,1 P. Muiesan.1

    1The Liver Unit, Queen Elizabeth Hospital, Birmingham, United Kingdom; 2Nephrology and Dialysis Unit, Sapienza University of Rome, Rome, Italy; 3Department of Health Informatics, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom; 4Department of Nephrology and Transplantation, Queen Elizabeth Hospital, Birmingham, United Kingdom; 5NIHR Birmingham Liver Biomedical Research Unit and Centre for Liver Research, University of Birmingham, Birmingham, United Kingdom.

    Aim of the study is to assess the incidence of acute kidney injury (AKI) and chronic kidney disease (CKD) after liver transplantation (LT) in DCD…
  • 2016 American Transplant Congress

    Pharmacist Impact on Medication Errors in a Chronic Kidney Transplant Clinic.

    K. Covert,1 C. Mardis,1 J. Fleming,1 A. Mardis,1 H. Meadows,1 N. Pilch,1 P. Mohan,2 M. Posadas,2 M. Salazar,2 T. Srinivas,2 G. Mour,2 D. Taber.1

    1Pharmacy, The Medical University of South Carolina, Charleston, SC; 2Transplant Nephrology, The Medical University of South Carolina, Charleston, South Carolina.

    Medication errors are associated with increased incidence of infection, rejection, and graft loss in kidney transplant recipients. This study aims to assess the impact of…
  • 2016 American Transplant Congress

    Morbid Obesity and Functional Status as Predictors of Surgical Complication After Renal Transplantation.

    T. Veasey, J. Fleming, S. Strout, R. Miller, N. Pilch, H. Meadows, C. Mardis, B. Mardis, P. Baliga, J. McGillicuddy, D. Taber.

    Medical University of South Carolina, Charleston, SC.

    Purpose: Surgical complications after renal transplant may impact patient morbidity and healthcare utilization. Identification of patients at risk would allow for planning allocation of resources…
  • 2016 American Transplant Congress

    The Influence of Rising Lab MELD on Vascular Invasion in HCC.

    K. Halazun, E. Przybyszewski, E. Verna, B. Samstein, A. Fox, R. Brown, J. Emond.

    Liver Transplant & HPB Surgery, Weill Cornell Medical College, NY, NY.

    Background Vascular invasion (VI) is one of the most important predictors of HCC recurrence. Although attempts to identify predictors of VI have been made, datasets…
  • 2016 American Transplant Congress

    Anti-Angiotensin II Type 1 Receptor Antibody Reduction with Proteasome Inhibitor-Based Desensitization.

    A. Girnita, E. Portwood, P. Brailey, S. Tremblay, R. Alloway, E. Woodle.

    University of Cincinnati, Cincinnati.

    Background. Desensitization results have largely focused on effects on anti-HLA antibody (HLA-Ab) and anti-ABO antibody levels. Anti-angiotensin II type 1 receptor antibody (AT1R-Ab) has recently…
  • 2016 American Transplant Congress

    Normothermic Ex Vivo Liver Perfusion (NEVLP) Using Steen Solution as Preservation Technique for Liver Transplantation-First Clinical Results.

    M. Selzner, N. Goldaracena, J. Echeverri, I. Linares, M. Kaths, N. Selzner, M. Cattral, E. Renner, A. Ghanekar, L. Lilly, P. Greig, I. McGilvray, D. Grant.

    Surgery, Toronto General Hospital, Toronto, Canada.

    The European trial investigating NEVLP as preservation technique for liver transplantation uses Gelafusine, a non-FDA approved bovine derived gelatin-based perfusion solution. In contrast, we report…
  • 2016 American Transplant Congress

    Assessment of Chikungunya IgM Prevalence Among Deceased Organ and Tissue Donors Using Two Enzyme Immunoassay (EIA) Kits.

    H. Prince, M. Altrich, M. Nowicki.

    Viracor-IBT Laboratories, Los Angeles, CA.

    Study Purpose: The emergence of Chikunungya virus (ChikV) infection in the western hemisphere has raised concerns of donor-derived transmission. We assessed the prevalence of recent…
  • 2016 American Transplant Congress

    Association of Cytomegalovirus-Specific T Cell-Mediated Immunity with the Risk of CMV Infection Occurrence in Kidney Transplant Recipients.

    D. Dęborska-Materkowska,1 A. Perkowska-Ptasińska,1 A. Sadowska,1 D. Sitarek,1 J. Gozdowska,1 M. Ciszek,2 M. Serwańska-Świętek,3 A. Jóźwik,3 P. Domagała,3 A. Kwiatkowski,3 M. Durlik.1

    1Department of Transplantation Medicine, Nephrology and Internal Diseases, Warsaw Medical University, Warsaw, Poland; 2Department of Immunology, Transplantology and Internal Diseases, Warsaw Medical University, Warsaw, Poland; 3Department of General and Transplantation Surgery, Warsaw Medical University, Warsaw, Poland.

    Introduction CMV remains the significant cause of morbidity in transplant recipients. Despite universal prophylaxis, late CMV infection occurs in high proportion of kidney transplant recipients.…
  • 2016 American Transplant Congress

    Foxp3 Controls Oxidative Phosphorylation in Regulatory T Cells.

    U. Beier,1 A. Angelin,2 J. Jiao,1 H. Xiao,1 L. Wang,3 S. Dahiya,3 A. Wells,3 D. Wallace,2 W. Hancock.3

    1Pediatric Nephrology, Children's Hospital of Philadelphia and University of Pennsylvania, Philadelphia, PA; 2Center for Mitochondrial and Epigenomic Medicine, Children's Hospital of Philadelphia, Philadelphia, PA; 3Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia and University of Pennsylvania, Philadelphia, PA.

    Current immunosuppressive therapies are limited by non-specificity and toxicities, and new pharmacologic approaches to immunosuppressive therapies are needed. Many T cell subsets have distinct metabolic…
  • 2016 American Transplant Congress

    NK Cells Are Required in B-Cell Dependent, Antibody Mediated Islet Transplant Tolerance.

    C. Schuetz, K. Lee, L. Kojima, L. Washburn, L. Liu, W.-H. Liu, J. Kim, J. Markmann.

    Dept of Surgery, Transplant Surgery Division, Massachusetts General Hospital, Boston, MA.

    Immunologic tolerance to islets has been achieved in various rodent models using antibodies directed at CD45RB and Tim-1. We have shown that this tolerance mechanism…
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