ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Kidney Survival Outcomes in Combined Intestinal-Kidney Transplant: An Analysis of the UNOS/OPTN Database 2000-2014.

    A. Sharfuddin, T. Taber, M. Yaqub, I. Moinuddin, A. Khalil, O. Adebiyi, M. Mujtaba.

    Medicine/Nephrology, Indiana University, Indianapolis.

    Background: Intestinal transplants (isolated/modified/multi-visceral) carry a high morbidity and mortality. Kidney outcomes after combined intestinal (IT) with kidney transplant (CIKT) remain largely uninvestigated.Methods: The UNOS…
  • 2016 American Transplant Congress

    Activation of Alloreactive T Cells by Allogeneic Exosomes and Cells Cross-Dressed with Allogeneic MHC Molecules.

    M. Babiker-Mohamed, J. Marino, P. Crosby, G. Benichou.

    Department of Surgery, Center for Transplantation Sciences, Massachusetts General Hospital & Harvard Medical School, Boston, MA.

    Our recent studies have documented the presence of high numbers of recipient antigen presenting cells (APCs) displaying donor MHC molecules (cross-dressed) on their surface after…
  • 2016 American Transplant Congress

    Bile Acid Signaling Affects Metabolism and Prolongs Allograft Survival in Obese Recipients.

    M. Quante, A. ElKhal, M. Seyda, J. Schuitenmaker, H. Uehara, S. Tullius.

    Division of Transplant Surgery & Transplant Surgery Research Laboratory, Brigham and Women's Hospital / Harvard Medical School, Boston, MA.

    Although obesity has been linked to impaired transplant outcomes, underlying mechanisms and consequences of obesity on alloimmunity are only poorly understood.Allogenic skin transplantations were performed…
  • 2016 American Transplant Congress

    In Vitro Reactivity of CD4+ T Cells Subsets from Hosts with Antigen Specific Transplant Tolerance Mediated by CD4+CD25+T Cells.

    B. Hall, C. Robinson, K. Plain, N. Verma, G. Tran, N. Carter, M. Nomura, R. Boyd, S. Hodgkinson.

    Immune Tolerance Laboratory, UNSW Australia, Sydney, NSW, Australia.

    In animals with transplant tolerance without lympho-hemopoietic chimerism peripheral T cells reactive to donor are not deleted, but their capacity to effect rejection is inhibited…
  • 2016 American Transplant Congress

    Older Patients Reliably Participate in Automated Living Donor Follow Up Rather Than Avoiding This New Technology.

    H. Braun, M. Parente, R. Hirose, G. Roll.

    Surgery, University of California-San Francisco, San Francisco, CA.

    Introduction: UCSF implemented automated living donor follow up to increase access to patients, improve communication, efficiency of data collection, and UNOS compliance. Using a modified…
  • 2016 American Transplant Congress

    Does Social Support Predict Clinical Outcomes Post-Transplantation? A Systematic Review and Meta-Analysis.

    K. Ladin,1 A. Daniels,1 M. Osani,2 R. Bannuru.2

    1Occupational Therapy, Tufts University, Medford, MA; 2Tufts Medical Center, Boston, MA.

    Background: Although social support is used to determine eligibility, the relationship between social support and medication nonadherence remains unclear. We examined the predictive value of…
  • 2016 American Transplant Congress

    Exome Sequencing and HLA-Independent Prediction of Long-Term Kidney Allograft Function.

    L. Mesnard,1,3,6 T. Muthukumar,2,9 M. Burbach,2 C. Li,2 H. Shang,4 D. Dadhania,2,3 J. Lee,2,3 V. Sharma,2 J. Xiang,4 M. Carmagnat,5 C. Suberbielle,5 N. Ouali,6 E. Rondeau,6,1 J. Friedewald,8 M. Abecassis,7 M. Suthanthiran,2,9 F. Campagne.3

    1UMR1155, INSERM, Paris, France; 2Division of Nephrology and Hypertension, New York Presbyterian Hospital, New York; 3Department of Physiology and Biophysics, The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, New York, NY; 4Genomics Core Facility, Weill Cornell Medical College, New York, NY; 5Laboratoire d'histocompatibilité Hôpital Saint Louis, APHP, Paris, France; 6Service des Urgences Néphrologiques et Transplantation Rénale, APHP, Paris, France; 7Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, IL; 8Northwestern University Feinberg School of Medicine, Chicago, IL; 9Department of Transplantation Medicine, Weill Cornell Medical College, New York, NY.

    Current strategies to improve graft outcome following kidney transplantation consider information at the HLA loci. We asked whether information outside of the HLA loci can…
  • 2016 American Transplant Congress

    Validation of the Newly Developed North America Islet Donor Scoring System in the Medium Volume Islet Transplant Center.

    J. Solomina,1 S. Matosz,1 M. Sledzinski,2 J. Golebiewska,3 O. Savaril,1 L.-J. Wang,4 T. Kin,5 K. Golab,1 S. Ramachandran,1 M. Tibudan,1 L. Schenck,1 W. Chon,6 C. Thomas,6 P. Witkowski.1

    1Surgery, University of Chicago, Chicago, IL; 2Surgery, Medical University of Gdansk, Gdansk, Poland; 3Internal Medicine, Medical University of Gdansk, Gdansk, Poland; 4Surgery, University of Illinois, Chicago, IL; 5Surgery, University of Alberta, Edmonton, AB, Canada; 6Medicine, University of Chicago, Chicago, IL.

    Background.North America Islet Donor Scoring (NAIDS) system has been recently developed for selection of the optimal pancreas donor based on analysis of the results from…
  • 2016 American Transplant Congress

    Long-Term Efficacy and Safety of Everolimus Based Immunosuppression on De Novo Kidney Transplantation with 7 Years Follow-Up.

    Y. Watarai, M. Okada, K. Futamura, T. Nagai, T. Yamamoto, M. Tsujita, T. Hiramitsu, N. Goto, S. Narumi, T. Kobayashi.

    Transplant Surgery, Nagoya Daini Red Cross Hospital, Nagoya, Aichi, Japan; Kidney Transplant Surgery, Aichi Medical University, Nagoya, Aichi, Japan.

    Purpose: Long-term efficacy and safety of everolimus (EVR) based immunosuppression for de novo kidney transplant recipient who were involved in A1202 study from our institute…
  • 2016 American Transplant Congress

    Steroid Free Immunosuppression and Clinical Outcomes in Recipients of Deceased Donor Kidney Transplant with Positive Flow Cytometry Crossmatch.

    O. Adebiyi, T. Taber, W. Goggins, D. Mishler, M. Yaqub, A. Sharfuddin.

    Indiana University, Indianapolis.

    Background: Positive flow cytometry crossmatch (FCXM) is considered a high immunologic risk for transplantation. Available studies reporting outcomes in positive FCXM kidney transplants were done…
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