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Early Posttransplant Complications Following Abo-Incompatible Kidney Transplantation.

L. Rostaing,1,2,3 A. Allal,1 H. Naciri Benami,1 Z. Abdulrahman,1 L. Esposito,1 F. Sallusto,1 N. Doumerc,1 X. Game,1 B. Debiol,1 N. Congy,1 N. Kamar.1,3,4

1Néphrologie et Transplantation d'Organes, CHU Rangueil, Toulouse, France
2INSERM U 563, CHU Purpan, Toulouse, France
3Faculté
de Médecine de Rangueil, Université
Toulouse III Paul Sabatier, Toulouse, France
4INSERM U1043 CNRS UMR 5282, CHU Purpan, Toulouse, France.

Meeting: 2016 American Transplant Congress

Abstract number: A267

Keywords: Kidney transplantation, Plasmapheresis

Session Information

Date: Saturday, June 11, 2016

Session Name: Poster Session A: Poster Session III: Kidney Complications-Other

Session Time: 5:30pm-7:30pm

 Presentation Time: 5:30pm-7:30pm

Location: Halls C&D

Related Abstracts
  • Infectious Complications in ABO Incompatible Kidney Transplantation Recipient According to the Rituximab Dose
  • Early Complications after ABO Incompatible Kidney Transplantation: A National Database Study

Introduction: Many studies or registries particularly in Japan, but also in Western Europe, have shown that long-term results from ABO-incompatible (ABOi) living-kidney transplantation are as good as those observed for ABO-compatible (ABOc) living-kidney transplantation.

However, it has been reported more posttransplant complications in ABOi patients, such as bleedings or infections.

Methodology: In our single-center retrospective study we assessed all relevant complications occurring within the first 6 months posttransplantation in 44 ABOi and in 44 matched ABOc patients. All patients were comparable at baseline except that ABOi patients had greater immunological risks.

Results: During the 6-month posttransplant period, more ABOi patients presented with postoperative bleeds, thus requiring significantly more blood transfusions. Bleeds were associated with significantly lower values of fibrinogen, platelets, prothrombin time, and hemoglobin levels in the immediate pretransplant period.

Significantly more BK-virus infections occurred in the ABOi group.

Surgical complications, patient- and graft-survival rates, and kidney-function statuses were similar between both groups at 6 months posttransplantation.

Conclusion: We conclude that impairment of hemostatic factors in ABOi patients at pretransplant explained the increased risk of a bleeding episode at posttransplant.

CITATION INFORMATION: Rostaing L, Allal A, Naciri Benami H, Abdulrahman Z, Esposito L, Sallusto F, Doumerc N, Game X, Debiol B, Congy N, Kamar N. Early Posttransplant Complications Following Abo-Incompatible Kidney Transplantation. Am J Transplant. 2016;16 (suppl 3).

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To cite this abstract in AMA style:

Rostaing L, Allal A, Benami HNaciri, Abdulrahman Z, Esposito L, Sallusto F, Doumerc N, Game X, Debiol B, Congy N, Kamar N. Early Posttransplant Complications Following Abo-Incompatible Kidney Transplantation. [abstract]. Am J Transplant. 2016; 16 (suppl 3). https://atcmeetingabstracts.com/abstract/early-posttransplant-complications-following-abo-incompatible-kidney-transplantation/. Accessed February 26, 2021.

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