ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Deceased Organ Donors with Zero Organs Transplanted: Why and How Can We Improve?

    P. Lange,1 S. Rudich,1 N. Obaseki,1 J. Punch.2

    1Medical Division, Gift of Life Michigan, Ann Arbor, MI; 2Surgery, University of Michigan, Ann Arbor, MI.

    Organ recovery professionals and donor hospitals are under intense pressure to go to whatever lengths necessary to provide transplantable organs. However, such a mentality can…
  • 2016 American Transplant Congress

    A Randomized-Controlled Trial Comparing the Efficacy of CYP3A5 Genotype-Based with Bodyweight-Based Tacrolimus Dosing After Living Donor Kidney Transplantation.

    N. Shuker,1,2 R. Bouamar,2 R. van Schaik,3 M. Clahsen -van Groningen,4 J. Damman,5 C. Baan,1 J. van de Wetering,1 A. Rowshani,1 W. Weimar,1 T. van Gelder,1,2 D. Hesselink.1

    1Internal Medicine, Erasmus Medical Centre, Rotterdam, Netherlands; 2Hospital Pharmacy, Erasmus Medical Centre, Rotterdam, Netherlands; 3Clinical Chemistry, Erasmus Medical Centre, Rotterdam, Netherlands; 4Pathology, Erasmus Medical Centre, Rotterdam, Netherlands; 5Pathology, Academic Medical Centre, Amsterdam, Amsterdam, Netherlands.

    Patients expressing the cytochrome P450 (CYP) 3A5 gene require a higher tacrolimus dose to achieve therapeutic exposure compared with non-expressers. This randomized-controlled study investigated if…
  • 2016 American Transplant Congress

    Elderly Kidney Transplant Recipients Need Optimized Immunosuppression According to Comorbidity and Infection.

    E. Kang,1 S. Park,1 S. Park,1 S. Yang,2 I. Jung,3 S.-K. Park,4 Y. Kim,5 D.-J. Han,1 Y. Kim,1 J. Lee.6

    1Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea; 2Kidney Research Institute, Seoul National University College of Medicine, Seoul, Korea; 3Department of Surgery, Seoul National University Boramae Medical Center, Seoul, Korea; 4Department of Internal Medicine, Asan Medical Center and University of Ulsan College of Medicine, Seoul, Korea; 5Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea; 6Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Korea.

    Backgrounds: The numbers of elderly kidney transplantation is increasing, but there are limited studies about the use of immunosuppressant in this group. We investigated the…
  • 2016 American Transplant Congress

    The Role of Short-Term Ventricular Assist Device in Patients with Cardiogenic Shock – Is It Really a Solution?

    A. Popov, M. Zeriouh, S. Anton, W. Alexander, Z. Bartlomiej, D. Garcia, P. Mohite, A. Padukone, A. Koch, O. Ananiadou, L. Fazekas, A. Simon.

    Department of Cardiothoracic Transplantation and Mechanical Circulatory Support, Royal Brompton & Harefield NHS Foundation Trust, London, United Kingdom.

    Background: Low cardiac output syndrome is associated with significant mortality. In patients with refractory low cardiac output left ventricular assist devices (VAD) are used to…
  • 2016 American Transplant Congress

    Prednisone Wean After Dual Heart and Kidney Transplantation: Is There a Risk?

    D. Chang, J. Patel, M. Kittleson, T. Aintablian, L. Czer, D. Ramzy, J. Kobashigawa.

    Cedars-Sinai Heart Institute, Los Angeles, CA.

    Background: Corticosteroids are the cornerstone of immunosuppressive therapy post transplant (Tx)but there are deleterious effects of long-term use. A protocol of corticosteroid weaning starting 6-12…
  • 2016 American Transplant Congress

    Life-Years Saved After Pediatric Liver Transplantation.

    R. Gruessner, A. Gruessner.

    SUNY Upstate Medical University, Syracuse, NY.

    Introduction: Transplantation has provided tremendous progress for pediatric patients with liver failure.We determined the survival benefit for pediatric patients as reported to UNOS.Methods: In this…
  • 2016 American Transplant Congress

    The UK Kidney Donor Risk Index Score Predicts the Development of TRAS Post Deceased Donor Transplantation.

    M. Willicombe, A. Baheerathan, S. Moser, A. McLean, M. Hammady, W. Gedroyc, D. Taube.

    Imperial College Renal and Transplant Centre, Hammersmith Hospital, London, United Kingdom.

    Introduction: Transplant renal artery stenosis (TRAS) is a heterogeneous disorder with different subtypes and aetiologies, which include traditional cardiovascular and transplant specific risk factors. Whether…
  • 2016 American Transplant Congress

    Renal Transplant in Obese Recipients: Consideration of Donor and Recipient Factors Can Improve Outcomes.

    P. Stahler, J. Mezrich, G. Leverson, D. Kaufman, H. Sollinger.

    Division of Transplantation, University of Wisconsin-Madison, Madison, WI.

    Background: Obesity rates in the transplant population are increasing. Previous studies are limited by small sample sizes, short-term follow up, and conflicting results. Factors including…
  • 2016 American Transplant Congress

    Infections in De Novo Kidney Transplant Recipients Treated with the RANKL Inhibitor Denosumab: A Post-Hoc Analysis of the POSTOP Clinical Trial (NCT01377467).

    M. Bonani,1 D. Frey,2 J. Brockmann,3 T. Fehr,1 T. Müller,1 N. Graf,4 R. Wüthrich.1

    1Division of Nephrology, University Hospital Zurich, Zurich, Switzerland; 2Division of Rheumatology, University Hospital Zurich, Zurich, Switzerland; 3Division of Visceral and Transplantation Surgery, University Hospital Zurich, Zurich, Switzerland; 4Graf Biostatistics, Winterthur, Switzerland.

    Background: A major cause of morbidity and mortality in kidney transplant recipients are infections. In this post-hoc analysis of the POSTOP study we assessed all…
  • 2016 American Transplant Congress

    Increased Frequency of Post-Recovery Liver Reallocation: The Law of Unintended Consequences?

    J. Orlowski, C. Muse, J. Whaley, R. Squires.

    LifeShare of Oklahoma, Oklahoma City, OK.

    Background: In June 2013, U.S. liver allocation changed from a local-regional-national model to “Share 35”, broadening sharing to a regional level based upon recipient listed…
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