Am J Transplant, Volume 16, Suppl 3 Archives - Page 159 of 180 - ATC Abstracts

2016 American Transplant Congress
CD57+ CD4 T Cells Persist in the Periphery Following Kidney Transplantation.
J. Espinosa,^1,2 L. Stempora,¹ R. Townsend,³ A. Kirk.¹
¹Duke University, Durham; ²Emory University, Atlanta; ³Bristol-Meyers Squibb, Princeton.
Purpose: We have shown that CD57+PD1- CD4 T cells play a role in belatacept-resistant rejection, but their mechanism of action is incompletely defined. Potential mechanisms…
2016 American Transplant Congress
Reciprocity for Compatible Pair Participation in Kidney Paired Donation.
J. Gill,¹ M.-C. Fortin,² C. Rose,¹ E. Cole,³ K. Tinckam,³ J. Gill.¹
¹Nephrology, UBC, Vancouver, BC, Canada; ²Nephrology, CHUM, Montreal, QC, Canada; ³Nephrology, UHN, Toronto, ON, Canada.
Participation of ABO and HLA compatible pairs (CPs) in kidney paired donation (KPD) could significantly increase living donor (LD) transplantation (TX). CPs may be more…
2016 American Transplant Congress
Pre-Transplant Cardiovascular Risk Factors Affect Kidney Allograft Survival: A Multi-Center Study in Korea.
J. An,^1,2 S. Ahn,³ E. Bae,² E. Kang,² H.-L. Kim,⁴ Y.-J. Kim,⁵ Y. Oh,^1,2 C. Lim,^1,2 Y. Kim,² Y. Kim,⁶ J. Lee.^1,2
¹Division of Nephrology, Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Korea; ²Division of Nephrology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea; ³Department of Preventive Medicine, Yonsei University Wonju College of Medicine, Wonju, Gangwon-do, Korea; ⁴Division of Cardiology, Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Korea; ⁵Division of Cardiology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea; ⁶Department of Surgery, Asan Medical Center and University of Ulsan College of Medicine, Seoul, Korea.
Background - Pre- or post-transplant cardiovascular (CV) risk factors affect the development of CV events even after successful kidney transplantation (KT). However, the impact of…
2016 American Transplant Congress
KDPI Outcomes and Discard Rates – The Contradiction of the U.S. and European Approach.
L. Lehner, A. Kleinsteuber, F. Halleck, D. Khadzhynov, M. Duerr, K. Budde, O. Staeck.
Dept. of Nephrology CCM, Charite Berlin, Berlin, Germany.
Introduction: Only a few data exist on the KDPI in European patients (pts). We evaluated the influence of donor factors assessed by the KDPI on…
2016 American Transplant Congress
Ibrutinib Suppresses Alloantibody Responses in A Mouse Model of Allosensitization: A Preliminary Report.
G. Wu, I. Kim, N.-N. Chai, A. Klein, S. Jordan.
CTC/Surgery, Cedars-Sinai Medical Center, Los Angeles, CA.
Background Ibrutinib is a Bruton tyrosine Kinase (BTK) antagonist that inhibits B cell receptor (BCR) signaling, therefore blocking B cell activation. Ibrutinib is approved by…
2016 American Transplant Congress
Single Cell Profiling of Th9 Cells Allows Identification of Functionally Different Subsets.
K. Stanko, J. Schumann, K. Vogt, S. Schlickeiser, C. Appelt, B. Sawitzki.
Institute of Medical Immunology, Charite University Medicine, Berlin, Germany.
T helper type 9 (Th9) cells represent a distinct subset of CD4+ effector T cells that is characterized by high secretion of interleukin (IL)-9. Protective…
2016 American Transplant Congress
Effect of Isolated Intraperitoneal Sirolimus Treatment on the Kidneys of C57BL/6 Mice.
B. Kim,^1,3 Y. Cho,³ H. Lee,³ D. Joo,^2,3 K. Huh,^2,3 M. Kim,^2,3 Y. Kim.^2,3
¹Nephrology Division, Department of Internal Medicine, Severance Hospital, Yonsei University Health System, Seoul, Republic of Korea; ²Department of Transplantation Surgery, Severance Hospital, Yonsei University Health System, Seoul, Republic of Korea; ³The Research Institute for Transplantation, Seoul, Republic of Korea.
Sirolimus, a mammalian target of rapamycin inhibitor, is widely used in transplantation. However, the mechanism by which sirolimus induces adverse effects such as proteinuria and…
2016 American Transplant Congress
Influence of Pancreas Import and Cold Ischemia on Outcomes Following Pancreas Transplantation.
M. Khan,¹ H. El-Hennawy,¹ J. Rogers,¹ A. Farney,¹ G. Orlando,¹ A. Reeves-Daniel,² A. Palanisamy,² R. Stratta.¹
¹Surgery, Wake Forest, Winston-Salem, NC; ²Internal Medicine, Wake Forest, Winston-Salem, NC.
Proposed changes in pancreas transplant (PT) allocation may improve organ sharing but increase cold ischemia time (CIT). Methods: We performed a single center, retrospective study…
2016 American Transplant Congress
Mechanical Thrombectomy for the Treatment of Pancreas Transplant Venous Thrombosis: A Single Center Experience.
S. Shin,¹ H. Ko,² K. Ko,² Y. Kim,¹ J. Choi,¹ J. Jung,¹ D. Han.¹
¹General Surgery, Asan Medical Centere, Seoul, Republic of Korea; ²Radiology, Asan Medical Center, Seoul, Republic of Korea.
The aim of this study is to investigate the safety and efficacy of mechanical thrombectomy used as a tool for graft rescue in patients with…
2016 American Transplant Congress
Absence of Acute Allograft Rejection in the Early Post Operative Period in a Full Face VCA Recipient with a Positive B-Cell Flow Cytometric Crossmatch Utilizing an Induction Immunosuppression Regimen Including Anti-thymocyte and Anti-CD20 Agents.
B. Gelb,³ M. Plana,¹ D. Dadhania,² M. Suthanthiran,² J. Diaz-Siso,¹ E. Rogriguez.¹
¹Plastic and Reconstructive Surgery, NYU Langone, New York; ²Rogosin Institute, New York; ³Transplant Surgery, NYU Langone, New York.
Background: The presence of donor-specific antibodies (DSA) to human leukocyte antigen (HLA) convey increased risk of allograft rejection. Patients suffering full-thickness burns to the face…