ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Reduced Incidence of Rejection in AB0-incompatible Kidney Transplantation – Five Year Follow-Up in a Single Center.

    A. Weidemann, F. Karpf, T. Dienemann, K. Birkner, J. Jacobi, K.-U. Eckardt.

    Nephrology and Hypertension, Universitaet Erlangen-Nuernberg, Erlangen, Germany.

    Introduction:Living kidney donation is the method of choice to expand the donor pool in times of severe organ shortage. In many centers, AB0-incompatible kidney transplantation…
  • 2016 American Transplant Congress

    Biopsies for Delayed Graft Function After Alemtuzumab Induction in Kidney Transplantation: The Incidence of Early Rejection After Alemtuzumab Is Very Low but Not Negligible.

    E. McGuire, C. Roufosse, T. Cook, D. Ashby, T. Cairns, J. Galliford, M. Willicombe, D. Taube, A. McLean.

    Imperial Kidney & Transplant Centre, Hammersmith Hospital, Imperial College Healthcare, London, United Kingdom.

    IntroductionUK practice advocates transplant biopsy (Bx) at day 7, then weekly in the presence of delayed graft function (DGF) because if missed, early rejection adversely…
  • 2016 American Transplant Congress

    Cytokine Networks in Kidney Transplant Patients.

    R. Sabat,1 E. Witte,1 P. Reinke,2 K. Wolk,1 N. Babel.3,4

    1Interdisciplinary Group Molecular Immunopathology, and Psoriasis Research and Treatment Center, Dermatology/Medical Immunology, Charite University Medicine Berlin, Berlin, Germany; 2Department of Nephrology and Berlin-Brandenburg Center for Regenerative Therapies, Charite University Medicine Berlin, Berlin, Germany; 3Medical Clinic I, Marien Hospital Herne, University Clinic Ruhr-University Bochum, Herne, Germany; 4Berlin-Brandenburg Center for Regenerative Therapies, Charite University Medicine Berlin, Berlin, Germany.

    As key mediators of the intercellular communication, cytokines play a crucial role in many processes following transplantation, including inflammation, tissue regeneration, and anti-microbial defense. Locally…
  • 2016 American Transplant Congress

    Assessing the Role of Everolimus in Reducing Hepatocellular Carcinoma Recurrence After Living Donor Liver Transplantation for Patients within UCSF Criteria: Re-Inventing the Role of Mammalian Target of Rapamycine Inhibitors.

    L.-B. Jeng, A. Thorat, H.-R. Yang, T.-H. Chen, S.-C. Hsu.

    Organ Transplantation, China Medical University Hospital, Taichung, Taiwan.

    The antineoplastic effects of everolimus(EVR) in adjuvant to its conventional immunosuppressive role in post-transplant setting can theoretically reduce the tumor recurrence in hepatocellular carcinoma(HCC)patients undergoing…
  • 2016 American Transplant Congress

    Cytokine Storm in Acute Post-Hepatectmy Phase Associates with Liver Injury and Impaired Liver Regeneration.

    Y. Xu,1,2 N. Navarro-Alvarez,1 J. Dong,2 J. Markmann,1 H. Yeh.1

    1Transplantation Division, Massachusetts General Hospital, Boston, MA; 2Department of Hepatobiliary Surgery, Chinese PLA General Hospital, Beijing, China.

    Background Posthepatectomy liver failure and its transplant counterpart, small-for-size syndrome, remain poorly understood. Large increases in IL-6 are associated with poor allograft function and IL-6…
  • 2016 American Transplant Congress

    Quality of Postoperative Pain Care in Living Liver Donors.

    M. Mandell,1 A. Smith,2,6 D. Gordon,3 S. Holtzman,4 M. Dew,5 T. Howell,6 A. DiMartini,5 Z. Butt,8 M. Simpson,7 C. Freise,9 S. McCluskey,10 R. Fisher,11 J. Guaerra,12 K. Olthoff,13 E. Pomfret.7

    1U of Colorado, Denver; 2Arbor Research Collaborative for Health, Ann Arbor; 3U of Washington, Seattle; 4U of British Columbia, Okanagan, Canada; 5U of Pittsburgh, Pittsburgh; 6U of Michigan, Ann Arbor; 7Lahey, Burlington; 8Northwestern U, Chicago; 9U of California at San Francisco, San Francisco; 10U of Toronto, Toronto, Canada; 11Virginia Commonwealth U, Richmond; 12Columbia U, New York; 13U of Pennsylvania, Philadelphia.

    Background: Postoperative pain (POP) is the strongest predictor of chronic pain syndromes (Katz and Seltzer, Expert Rev Neurother 2009), however little is known about POP…
  • 2016 American Transplant Congress

    Arteriolar Hyalinosis on Renal Transplant Protocol Biopsies Is Not Associated with Tacrolimus Exposure.

    S. Yilmaz,1 D. Shaffer,2 Y. Qazi,3 F. Shihab,4 K. McCague,5 D. Patel,5 F. Vincenti.6

    1University of Calgary, Calgary, AB, Canada; 2Vanderbilt University, Nashville, TN; 3University of Southern California, Los Angeles, CA; 4University of Utah, Salt Lake City, UT; 5Novartis Pharmaceuticals Corporation, East Hanover, NJ; 6University of California San Francisco, San Francisco, CA.

    Previous studies have implicated the development of arteriolar hyalinosis (AH) following kidney transplantation to chronic calcineurin inhibitor nephrotoxicity. Here, we examined the association between tacrolimus…
  • 2016 American Transplant Congress

    Chronic Infection by Hepatitis C Virus and the Development of Transplant Glomerulopathy.

    D. Regidor,1 S. Alexandru,5 M. Martínez,3 N. Polanco,4 E. González,4 A. Serrano,2 J. Morales.4

    1Nephrology, H.Virgen de la Salud, Toledo, Spain; 2Immunology, Instituto de Investigación H. Doce de Octubre, Madrid, Spain; 3Pathology, H.Doce de Octubre, Madrid, Spain; 4Nephrology, H.Doce de Octubre, Madrid, Spain; 5Nephrology, H.Rey Juan Carlos, Madrid, Spain.

    OBJETIVE: To demonstrate that chronic infection with the hepatitis C virus (HCV) is a risk factor for the development of transplant glomerulopathy in a large…
  • 2016 American Transplant Congress

    Early Posttransplant Complications Following Abo-Incompatible Kidney Transplantation.

    L. Rostaing,1,2,3 A. Allal,1 H. Naciri Benami,1 Z. Abdulrahman,1 L. Esposito,1 F. Sallusto,1 N. Doumerc,1 X. Game,1 B. Debiol,1 N. Congy,1 N. Kamar.1,3,4

    1Néphrologie et Transplantation d'Organes, CHU Rangueil, Toulouse, France; 2INSERM U 563, CHU Purpan, Toulouse, France; 3Faculté de Médecine de Rangueil, Université Toulouse III Paul Sabatier, Toulouse, France; 4INSERM U1043 CNRS UMR 5282, CHU Purpan, Toulouse, France.

    Introduction: Many studies or registries particularly in Japan, but also in Western Europe, have shown that long-term results from ABO-incompatible (ABOi) living-kidney transplantation are as…
  • 2016 American Transplant Congress

    Watch Out for the Guy with the Low EPTS Score: Nonadherence and Kidney Allograft Failure.

    A. Liu, K. Balabhadrapatruni, J. Augustine.

    Medicine, University Hospitals Case Medical School, Cleveland, OH.

    Background: Nonadherence is a known cause of rejection and kidney allograft failure. Our aim was to define risk factors for allograft loss related to nonadherence.…
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