2016 American Transplant Congress
Kidney Structural Characteristics as Predictors of Long-Term Kidney Function in Living Kidney Donors.
PurposeKidney structural characteristics may be predictive of long-term living donor outcomes such as a lower estimated Glomerular Filtration Rate (eGFR).MethodsAs part of the Renal and…2016 American Transplant Congress
Common Molecular Features of Human Kidney Transplant Rejection Reflect Mechanistic Sharing Between T Cell-Mediated and Antibody-Mediated Rejection.
1University of Queensland, Brisbane, Australia; 2University of Australia, Edmonton, Canada.
We previously reported the molecular features of human kidney transplant biopsies with T cell-mediated rejection (TCMR) (Am J Transplant 14(11):2565-76) and antibody-mediated rejection (ABMR) (Am…2016 American Transplant Congress
Reciprocity for Compatible Pair Participation in Kidney Paired Donation.
Participation of ABO and HLA compatible pairs (CPs) in kidney paired donation (KPD) could significantly increase living donor (LD) transplantation (TX). CPs may be more…2016 American Transplant Congress
Pre-Transplant Cardiovascular Risk Factors Affect Kidney Allograft Survival: A Multi-Center Study in Korea.
Background - Pre- or post-transplant cardiovascular (CV) risk factors affect the development of CV events even after successful kidney transplantation (KT). However, the impact of…2016 American Transplant Congress
KDPI Outcomes and Discard Rates – The Contradiction of the U.S. and European Approach.
Dept. of Nephrology CCM, Charite Berlin, Berlin, Germany.
Introduction: Only a few data exist on the KDPI in European patients (pts). We evaluated the influence of donor factors assessed by the KDPI on…2016 American Transplant Congress
Ibrutinib Suppresses Alloantibody Responses in A Mouse Model of Allosensitization: A Preliminary Report.
CTC/Surgery, Cedars-Sinai Medical Center, Los Angeles, CA.
Background Ibrutinib is a Bruton tyrosine Kinase (BTK) antagonist that inhibits B cell receptor (BCR) signaling, therefore blocking B cell activation. Ibrutinib is approved by…2016 American Transplant Congress
Single Cell Profiling of Th9 Cells Allows Identification of Functionally Different Subsets.
Institute of Medical Immunology, Charite University Medicine, Berlin, Germany.
T helper type 9 (Th9) cells represent a distinct subset of CD4+ effector T cells that is characterized by high secretion of interleukin (IL)-9. Protective…2016 American Transplant Congress
Effect of Isolated Intraperitoneal Sirolimus Treatment on the Kidneys of C57BL/6 Mice.
Sirolimus, a mammalian target of rapamycin inhibitor, is widely used in transplantation. However, the mechanism by which sirolimus induces adverse effects such as proteinuria and…2016 American Transplant Congress
Influence of Pancreas Import and Cold Ischemia on Outcomes Following Pancreas Transplantation.
1Surgery, Wake Forest, Winston-Salem, NC; 2Internal Medicine, Wake Forest, Winston-Salem, NC.
Proposed changes in pancreas transplant (PT) allocation may improve organ sharing but increase cold ischemia time (CIT). Methods: We performed a single center, retrospective study…2016 American Transplant Congress
Mechanical Thrombectomy for the Treatment of Pancreas Transplant Venous Thrombosis: A Single Center Experience.
The aim of this study is to investigate the safety and efficacy of mechanical thrombectomy used as a tool for graft rescue in patients with…
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