2016 American Transplant Congress
Defining Frailty in Liver Transplant Recipients.
PURPOSETo define frailty in the liver transplant (OLT) population to optimize care and assist in predicting post OLT outcomes.METHODSAll adult primary OLT patients from 01/2010…2016 American Transplant Congress
Risk Factors for Short and Long Term Mortality in High MELD Recipients.
The model for end-stage disease (MELD) score is used to stratify candidates for liver transplant (LT) based on objective measures. Since June 2013 with changes…2016 American Transplant Congress
The Effect of Body Mass Index on Lung Transplant Outcomes.
Background: Lung transplant (LTx) has the potential to effectively extend the life expectancy for patients with end-stage lung disease. Both high and low body mass…2016 American Transplant Congress
Randomized Controlled Trial of Mixed Acute Rejection Therapy in Renal Allografts: 3 Year Follow Up.
1U. of Cincinnati, Cincinnati; 2The Christ Hospital, Cincinnati.
Optimal therapy for mixed acute rejection (MAR) (defined as coexisting acute cellular and antibody mediated rejection) has not been defined. Rabbit antithymocyte globulin (rATG) has…2016 American Transplant Congress
Comparison of EDTA, DTT and Dilutions to Abrogate the Prozone Effect in Luminex-Based HLA Antibody Assays.
Department of Laboratory Medicine and Pathology, Mayo Clinic, Phoenix, AZ.
Mean fluorescence intensity (MFI) values obtained from Luminex-based single antigen bead (SAB) assays is a semi-quantitative result used to determine the relative strength of HLA…2016 American Transplant Congress
Breadth of HLA-Specific B Cell Reactivity and Frequency Assessed by a Novel Multiplex Bead Based Assay Predicts and Correlates with Rejection in Kidney Transplant Recipients.
Northwestern University, Chicago.
Introduction: Recipients with broad sensitization to HLA defined by a high percentage of Panel Reactive Antibodies (PRA) are at higher immunologic risk for poor graft…2016 American Transplant Congress
Alemtuzumab Induction Allows Better Rejection Free Graft Survival in Comparison to Basiliximab Although with Increased Post Transplant Viral Infections.
Introduction: 3C study concluded that in comparison to basiliximab, alemtuzumab induction reduces the risk of biopsy proven acute rejection (BPAR) in renal transplant recipients. In…2016 American Transplant Congress
Thoracic Simulated Allocation Modeling (TSAM) of Broader Sharing.
Heart allocation policy (OPTN policy 6) is in development. The Heart Subcommittee of the OPTN Thoracic Committee developed a 6-tiered medical urgency algorithm, then investigated…2016 American Transplant Congress
Matrix Metalloproteinase-2 (MMP-2) Activity Protects Against Hepatic Ischemia Reperfusion Injury Through MMP-9-Dependent and MMP-9-Independent Mechanisms.
The Dumont-UCLA Transplant Center, Los Angeles.
Matrix Metalloproteinases (MMPs) are a family of proteinases with key roles in tissue homeostasis, inflammation and repair. We have recently shown that MMP-9 and MMP-2,…2016 American Transplant Congress
Bioinformatic Analysis of Pathways Mediating Clusterin Functions in Kidney Cells Under Normoxia and Hypoxia.
Department of Urologic Sciences, University of British Columbia, Vancouver, BC, Canada.
Background: Clusterin (CLU) is a chaperone-like protein and contributes to the resistance of the kidney to ischemia-reperfusion injury (IRI), however its pathways are not fully…
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