ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Motivation and Stress Associated with Non-Directed Kidney Donation.

    J. Wiseman,1 D. Berglund,1 C. Jacobs,1 D. Larson,1 C. Garvey,1 M. Vogues, S. Rein,1 O. Sanchez,1 C. Radecki Breitkopf,2 H. Ibrahim,1 A. Matas.1

    1U of MN, Mpls; 2Mayo Clinic, Rochester.

    Background: Nondirected kidney donors (NDDs) are unique in that they have the risks of nephrectomy but often do not have the benefit of seeing the…
  • 2016 American Transplant Congress

    VDJ Immune Repertoire Sequencing Predicts Patients at Risk of Alloimmune Injury.

    M. Sirota,1 T. Sigdel,1 S. Boyd,2 A. Fire,2 M. Sarwal.1

    1Surgery and Bioinformatics, UCSF, San Francisco, CA; 2Genetics, Stanford University, Palo Alto, CA.

    Background: The complex repertoire of immune receptors generated by B cells enables allo-recognition in the context of transplantation across HLA barriers, and is a major…
  • 2016 American Transplant Congress

    Is Prolonged Cold Ischemia a Contraindication to Using Kidneys from Acute Kidney Injury Donors?

    M. Khan,1 A. Carrier,1 H. El-Hennawy,1 A. Farney,1 J. Rogers,1 G. Orlando,1 A. Reeves-Daniel,2 A. Palanisamy,2 M. Gautreaux,3 S. Iskandar,3 W. Doares,4 S. Kaczmorski,4 R. Stratta.1

    1Surgery, Wake Forest, Winston-Salem, NC; 2Internal Medicine, Wake Forest, Winston-Salem, NC; 3Pathology, Wake Forest, Winston-Salem, NC; 4Pharmacy, Wake Forest, Winston-Salem, NC.

    Elevated deceased donor (DD) serum creatinine (SCr) levels and prolonged cold ischemia time (CIT) are major independent reasons for kidney discard following organ recovery. Many…
  • 2016 American Transplant Congress

    Center Level Analysis of Changes in Living Donor Transplant Rates in the United States.

    D. Keith, A. Nishio Lucar, G. Vranic.

    Medicine, Division of Nephrology, University of Virginia, Charlottesville, VA.

    Rates of living donor kidney transplantation have been declining in the United States since 2003. Tremendous variation exists in the rate of living donor transplantation…
  • 2016 American Transplant Congress

    Renal Allograft Outcomes with Renal Artery Angioplasty and/or Stenting in Transplant Renal Artery Stenosis.

    E. Tantisattamo,1 A. Chokechanachaisakul,2 S. Pitukweerakul,3 P. Ratanasrimetha,4 A. Shetty,2 O. Traitanon,5 L. Gallon.2

    1Oakland University William Beaumont School of Medicine, Royal Oak, MI; 2Northwestern University, Chicago, IL; 3Presence St. Francis Hospital, Evanston, IL; 4Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand; 5Thammasart University Hospital, Pathumthani, Thailand.

    Background: The renal allograft function and blood pressure (BP) control after renal artery angioplasty±stenting for transplant renal artery stenosis (TRAS) is unclear. We aim to…
  • 2016 American Transplant Congress

    PD-L1/PD-L2-Expressing B-1a Cells Inhibit Allo-Reactive T Cells in Mice.

    T. Hirose,1,2 Y. Tanaka,1 H. Ohdan.1

    1Transplant Surgery, Hiroshima University, Hiroshima, Japan; 2Urology, Hokkaido University, Sapporo, Hokkaido, Japan.

    Donor lymphocyte infusion (DLI) induces donor-specific hypo responsiveness or immune-tolerance among allo-reactive T cells in different organ transplantation models. However, the optimal cell source or…
  • 2016 American Transplant Congress

    Sequential Analysis of Donor-Specific Antibodies and Pathological Findings Using Intravenous Immunoglobulin in a Highly Sensitized Rat Kidney Transplant Model.

    Y. Sawada,1 K. Omoto,2 N. Kohei,4 K. Kawanishi,3 M. Okumi,2 H. Ishida,2 T. Kazunari.2

    1Urology, Fukushima Rosai Hospital, Iwaki, Japan; 2Urology, Tokyo Women's Medical University, Tokyo, Japan; 3Pathology, Tokyo Women's Medical University, Tokyo, Japan; 4Urology, Shizuoka General Hospital, Shizuoka, Japan.

    Intravenous immunoglobulin (IVIG) has evolved widespread use for treatment of acute antibody-mediated rejection (AAMR) and desensitization in highly HLA-sensitized patients. However, sequential change of the…
  • 2016 American Transplant Congress

    Impact of Immunosuppressants on Inducing Regulatory T Cells in Human Allo-Immune Responses.

    Y. Tanaka, H. Ohdan.

    Transplant Surgery, Hiroshima University, Hiroshima, Japan.

    A better understanding of cytokine signaling pathways involving transcription factors of the STAT family in T cells responding to allostimulation will improve interpretation of immune-regulatory…
  • 2016 American Transplant Congress

    Long Term Results on Pancreas Transplant Beyond the Standard Indications, at a Single Center.

    D. Ramisch,1 N. Aguirre,1 F. Moss,2 P. Farinelli,1 R. Fortunato,2 L. Gutierrez,2 P. Barros Schelotto,1 H. Fraguas,3 P. Raffaele,2 G. Gondolesi.1

    1Instuto de Transplante Multiorganico, Hospital Universitario Fundacion Favaloro, Buenos Aires, Argentina; 2Unidad de Trasplante Renal y Nefrologia, Hospital Universitario Fundacion Favaloro, Buenos Aires, Argentina; 3Servicio de Cirugia Cardiovascular, Hospital Universitario Fundacion Favaloro, Buenos Aires, Argentina.

    Introduction: Simultaneous kidney-pancreas (SKP) transplantation has become the best treatment option for patients with end stage renal disease (ESRD) and type 1 diabetes (T1D). In…
  • 2016 American Transplant Congress

    Outcomes with Steroids Alone for Biopsy-Proven Pancreas Transplant Rejection.

    S. Salahuddin,1 B. Astor,1 S. Parajuli,1 A. Djamali,1 J. Odorico,2 D. Mandelbrot.1

    1Department of Nephrology, University of Wisconsin, Madison, WI; 2Department of Surgery, University of Wisconsin, Madison, WI.

    There is little published data on the response of pancreas rejection to steroids alone. We reviewed 42 pancreas transplant recipients between 01/1997 and 12/2013 at…
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