ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Single Center Experience with Robotic Kidney Transplantation for Recipients with BMI >40 kg/m2: A Comparison with the UNOS Registry.

    I. Tvetanov, S. Garcia Aroz, M. Spaggiari, J. Hoonbae, J. Oberholzer, E. Benedetti.

    Surgery, University of Illinois, Chicago, IL.

    Introduction:Obesity represents a barrier to kidney transplantation, but the increasing prevalence amongst renal failure patients has forced some centers to carefully consider such candidates. Morbidly…
  • 2016 American Transplant Congress

    Predictors of Urologic Complications After Pediatric En-Bloc Donor Kidney Transplantation.

    S. Kabagambe,1 A. De Mattos,2 R. Perez,1 C. Santhanakrishnan,1 J. Sageshima,1 C. Troppmann,1 J. McVicar.1

    1Surgery, University of California-Davis, Sacramento, CA; 2Transplant Nephrology, University of California-Davis, Sacramento, CA.

    Pediatric en-bloc kidney transplant (PEBKT) has expanded the donor pool. Association of donor characteristics and urologic complications is not well described. The objective of this…
  • 2016 American Transplant Congress

    The Effect of Immunosuppression Regimen on Iga Nephropathy Recurrence Post Kidney Transplantation.

    K. Koutroutsos,1 A. Kousios,1 L. Leighton,1 R. Charif,1 D. Goodall,1 T. Cook,2 J. Galliford,1 D. Taube,1 M. Loucaidou.1

    1Renal and Transplant Centre, Imperial Healthcare NHS Trust, London, United Kingdom; 2Department of Histopathology, Imperial Healthcare NHS Trust, London, United Kingdom.

    Background: Steroid sparing immunosuppression is increasingly used in order to avoid the many well-known side effects of steroids. It has been argued that steroid use…
  • 2016 American Transplant Congress

    Comparative Effectiveness of Cytomegalovirus Prevention Strategies in a Large Retrospective Cohort of Kidney Transplant Recipients.

    C. Santos, M. Saeed, D. Brennan, M. Olsen.

    Washington University School of Medicine, Saint Louis, MO.

    Background: While CMV prevention strategies have been studied in carefully selected groups of patients enrolled in randomized trials, their comparative effectiveness in real-world settings is…
  • 2016 American Transplant Congress

    Neuro-invasive Saint Louis Encephalitis Virus (SLEV) Infection in Solid Organ Transplant Recipients in a Non-Endemic Area.

    C. Hartmann, I. Qaqish, T. Grys, H. Vikram, M. Seville, R. Orenstein, S. Kusne, J. Blair, R. Patron.

    Infectious Disease, Mayo Clinic Arizona, Phoenix, AZ.

    Background:In the summer of 2015, three prior solid organ transplant recipients developed meningoencephalitis suggestive of West Nile virus (WNV) infection in the Phoenix area with…
  • 2016 American Transplant Congress

    Donor Specif Antibody (DSA) Kinetics in Patients with Antibody Mediated Rejection (AMR) Treated with Plasmapheresis and Bortezomib.

    L. Requião-Moura,1 M. Afonso,2 A. Sakashita,3 M. Silva,1 A. Matos,1 A. Pacheco-Silva.1

    1Kidney Transplant, Hospital Israelita Albert Einstein, São Paulo, Brazil; 2Histocompatibility Laboratory, Hospital Israelita Albert Einstein, São Paulo, Brazil; 3Blood Bank, Hospital Israelita Albert Einstein, São Paulo, Brazil.

    Backgroud: The best choice to treat AMR is not supported by several evidences, and recently the interest in drugs as Bortezomib has improved. Aim: Evaluted…
  • 2016 American Transplant Congress

    Graft Survival in Sensitized and Non-Sensitized Patients: Role of the Combination of Donor-Specific Antibodies and Acute Rejection.

    P. Souza,1 A. Aguirre,1 G. Bezerra,2 H. Rodrigues,2 F. Agena,1 D. David,1 F. de Paula,1 E. David-Neto,1 M. Castro.1

    1Renal Transplant Service, Hospital das Clínicas de São Paulo, Sao Paulo, Brazil; 2Immunology Laboratory, Instituto do Coração (InCor), Sao Paulo, Brazil.

    Background: Sensitized (S) patients have higher risk for acute rejection (AR), especially ABMR. DSA is a risk fator for ABMR, however, its impact on AR…
  • 2016 American Transplant Congress

    Chimeric Cell Transplantation for Treatment of Duchenne Muscular Dystrophy: A Preliminary Report.

    E. Szilagyi, E. Bryndza Tfaily, J. Cwykiel, M. Siemionow.

    Orthopaedic Surgery, University of Illinois at Chicago, Chicago.

    Background: Transplant of Chimeric Cells, created via ex vivo fusion of donor and recipient cells, represents a promising cell therapy option in the field of…
  • 2016 American Transplant Congress

    Tacrolimus (Tac), Rather Than Cyclosporine (CsA), Interacts with Insulin Resistance (IR) to Alter Key Transcription Factors for β-Cell Identity & Function without Altering NFAT Localization.

    J. Triñanes,1 A. Rodriguez,2 E. de Koning,1 J. de Fijter,1 F. Carlotti,1 A. Torres,2 A. de Vries,1 E. Porrini.2

    1Nephrology, Leiden University Medical Center, Leiden, Netherlands; 2CIBICAN, University of La Laguna, Tenerife, Spain.

    Inhibiting the calcineurin(CN)/NFAT-pathway in β-cells may contribute to posttransplant diabetes. The presumed higher diabetogenicity of Tac is thought to owe to an IC50 for CN…
  • 2016 American Transplant Congress

    aPC Pretreatment of hEPCR-Expressing PAECs Attenuates Endothelial Cell Damage and Thrombosis.

    C. Laird,1 B. French,1 D. Harris,1 X. Chang,1 D. Ayares,2 R. Pierson,1 A. Azimzadeh.1

    1Cardiac Surgery, University of Maryland School of Medicine, Baltimore, MD; 2Revivicor, Inc, Blacksburg, VA.

    IntroductionActivated Protein C (aPC), acting primarily through the human endothelial protein C receptor (hEPCR), mediates anti-thrombotic and anti-inflammatory cytoprotective effects in humans. We hypothesized that…
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