Am J Transplant, Volume 16, Suppl 3 Archives - Page 150 of 180 - ATC Abstracts

2016 American Transplant Congress
CD45RO+/CD62L- Effector Memory T Cells Mediate Depletion Resistant Allograft Rejection in Intestinal Transplant Recipients.
C. Cosentino, J. Kaiser, A. Shukla, C. Desai, R. Girlanda, J. Hawksworth, C. Matsumoto, M. Zasloff, T. Fishbein, A. Kroemer.
MedStar Georgetown Transplant Institute, Washington DC.
A. A high risk of acute cellular rejection (ACR) is one of the key factors limiting intestinal transplantation (ITx). An extremely poor prognosis is related…
2016 American Transplant Congress
Exosome-Like Vesicles Released in Association with Tissue Injury Trigger Anti-LG3 Production.
M. Dieudé,^1,2,3 J. Turgeon,^1,3 B. Yang,^1,2,3 L. Pomerleau,^1,3 K. Hamelin,^1,3 S. Lan,^1,2,3 S. Qi,^1,3 D. Gingras,^1,3 W. Dhari,¹ A. Rivard,¹ M.-J. Hébert.^1,2,3
¹Research Centre, Centre hospitalier de l'Université de Montréal, Montréal, Canada; ²Université de Montréal, Montréal, Canada; ³Canadian National Transplantation Research Program, Edmonton, Canada.
Pre-transplant levels of autoantibodies to perlecan/LG3 predict poor allograft outcomes in renal transplant patients. We showed previously thatapoptotic exosome-like vesicles (ApoExo) enhance anti-LG3 production and…
2016 American Transplant Congress
Aryl Hydrocarbon Receptor Expression Increases in Skin Graft-infiltrating Th1 and Treg Cells.
J. Fechner, W. Julliard, L. Owens, J. Mezrich.
Surgery, University of Wisconsin, Madison, WI.
Hypothesis: The expression of the aryl hydrocarbon receptor (AHR), a transcription factor activated by a variety of exogenous and endogenous ligands including the typtophan-metabolite kynuenine,…
2016 American Transplant Congress
Long-Term Islet Xenograft Survival Requires Effective Control of Early Xenogeneic IL-17 Response and Late Xenogeneic IFN-γ Response.
H. Kang,¹ S. Wang,² X. Zhang,³ A. Singh,⁵ L. Zhang,¹ W. Suarez-Pinzon,⁵ S. Miller,⁴ B. Hering,⁵ X. Luo.^1,3,4
¹Medicine, Northwestern University, Chicago, IL; ²Surgery, Tianjin Union Medical Center, Tianjin, China; ³Comprehensive Transplant Center, Northwestern University, Chicago, IL; ⁴Microbiology and Immunology, Northwestern University, Chicago, IL; ⁵Schulze Diabetes Institute, University of Minnesota, Minneapolis, MN.
Introduction: Tolerance induction for xenogeneic islet transplant remains a challenge. We have previously shown that peri-transplant infusion of donor cells treated with 1-ethyl-3-(3'-dimethylaminopropyl)-carbodiimide (ECDI) is…
2016 American Transplant Congress
Racial Disparities in Cognitive and Social Requirements Prior to Listing for Liver Transplant.
M. Jesse, E. Goldstein, T. Macaulay, N. Rebhan, C.-X. Ho, M. Bebanic, L. Shkokani, M. Abouljoud, A. Eshelman, A. Yoshida.
Transplant Institute, Henry Ford Health System, Detroit, MI.
Guidelines for liver transplant candidates outline increased engagement of social supports in the context of patient cognitive impairments. However, there is little direction when limitations…
2016 American Transplant Congress
Does Pre-Emptive Transplantation Improve Survival Compared to Transplantation After Dialysis Among Deceased Donor Kidney Recipients?
J. Tao, C. Wu, W. Bannister, M. Schnitzler, A. Bonagura, B. Laihinen, F. Irwin.
Complex Medical Conditions, Optum, UnitedHealth Group, Eden Prairie, MN; Surgery, St Louis University, St Louis, MO.
Previous studies have shown that pre-emptive transplantation of kidneys from living donors is associated with longer graft survival than those who have initiated dialysis prior…
2016 American Transplant Congress
Defining Ischemic Time in Lung Donation After Circulatory Determination of Cardiac Death.
D. Pratt,¹ Z. Kon,² A. Iacono,² J. Kim,² R. Reed,² I. Timofte,² J. Gammie,² S. Pham,² B. Griffith,² P. Sanchez.²
¹University of Maryland School of Medicine, Baltimore, MD; ²Division of Cardiac Surgery, University of Maryland, Baltimore, MD.
Background: Donation after circulatory determination of death (DCDD) promises to increase the number of available lungs for transplantation. Nevertheless, the metrics to define warm ischemic…
2016 American Transplant Congress
Virological Profile of Deceased Organ Donors in the UK.
M. Lawrance,¹ K. Davison,¹ I. Ushiro-Lumb,² S. Lattimore (deceased),¹ S. Brailsford.^1,2
¹NHSBT/PHE Epidemiology Unit, Public Health England, London, United Kingdom; ²NHS Blood & Transplant, London, United Kingdom.
Background: To date there has been no routine surveillance of infections in deceased solid organ donors in the UK. A national scheme to monitor infectious…
2016 American Transplant Congress
Significant Pharmacokinetic Interaction Between Everolimus and Tacrolimus in De Novo Renal Transplant Recipients.
H.-P. Chang,¹ C.-Y. Lee,² C.-C. Si,¹ M.-K. Tsai,² F.-L. Lin Wu.^1,3
¹Graduate Institute of Clinical Pharmacy, National Taiwan University, College of Medicine, Taipei, Taiwan; ²Surgery, National Taiwan University Hospital, College of Medicine, Taipei, Taiwan.
Studies on the effect of everolimus on tacrolimus pharmacokinetics (PK) were limited and the results were inconsistent. In contrast, studies showed there was little effect…
2016 American Transplant Congress
Outcomes of Hispanic Kidney Transplant Recipients Under a Cyclosporine versus Tacrolimus Based Immunosuppression Protocol.
P. West-Thielke, A. Lasky, J. Thielke, M. Campara, E. Benedetti.
University of Illinois, Chicago.
Purpose: In 2005, an internal retrospective study at our institution showed a higher incidence of post transplant diabetes mellitus (PTDM) in our Hispanic kidney transplant…