ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Skin as a Harbinger of Rejection of Underlying Structures in Vascularized Composite Allografts: Concordance or Discordance?

    L. Cendales,1 M. Levine,2 S. Bartlett,3 J. Cheeseman,1 C. Drachenberg,3 W. Hancock,4 M. Joshi,1 A. Kirk,1 F. Leoopardi,1 S. Levin,2 M. Uluer,3 A. Selim,5 M. Song,1 W. Twaddell,3 L. Wang,4 Z. Wang,2 R. Barth.3

    1Surgery, Duke University, Durham, NC; 2University of Pennsylvania, Philadelphia, PA; 3University of Maryland School of Medicine, Baltimore, MD; 4Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA; 5Pathology, Duke University, Durham, NC.

    Vascularized composite allografts (VCA) are composed of multiple tissue types. It has not been determined as to whether there is an immune hierarchy or differential…
  • 2016 American Transplant Congress

    Live Donor Kidney Transplantation of the Most Highly Sensitized Patients in the Era of Kidney Paired Donation.

    A. Bingaman,1 F. Wright,1 M. Kapturczak,1 L. Shen,1 C. Murphey.2

    1Transplant, Methodist Specialty and Transplant Hospital, San Antonio, TX; 2Southwest Immunodiagnostics, Inc., San Antonio, TX.

    Background: Despite effective kidney paired donation (KPD) programs, the most highly sensitized patients (calculated panel reactive antibody (cPRA) > 98%) remain significantly disadvantaged and accumulate…
  • 2016 American Transplant Congress

    Hepatitis C Patients in a Multicenter Study Who Received Living Donor Liver Transplants Are Likely to Have Increased Survival.

    J. Kim,1 K.-W. Lee,2 G.-W. Song,3 B.-H. Jung,3 H. Lee,4 N.-J. Yi,2 C. Kwon,1 S. Hwang,3 K.-S. Suh,2 J.-W. Joh,1 S.-K. Lee,1 S.-G. Lee.3

    1Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea; 2Department of Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea; 3Division of Hepatobiliary Surgery and Liver Transplantation, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea; 4Department of Surgery, Seoul National University Boramae Medical Center, Seoul, Korea.

    Background: No consensus has been reached regarding comparisons of outcomes for patients with hepatitis C virus (HCV) who received living donor liver transplantation (LDLT) versus…
  • 2016 American Transplant Congress

    NanoString Detection of Gene Signatures in Urine During Acute Cellular Rejection of Kidney Grafts.

    K. Keslar,1 A. Zmijewska,2 J. Andriga,2 K. Newell,3 R. Mannon,2 P. Heeger,4 R. Fairchild.1

    1Cleveland Clinic, Cleveland; 2UAB, Birmingham; 3Emory, Atlanta; 4MSSM, New York.

    Considerable effort has focused on identification of gene expression patterns that may assist in diagnosis of acute cellular rejection. The NanoString platform offers a novel…
  • 2016 American Transplant Congress

    Acute Allograft Glomerulopathy: A Distinct Form of Cellular Rejection.

    O. AL-Badri, M. Alexander, F. Cosio, L. Cornell.

    Mayo Clinic, Rochester, MN.

    Background: Acute allograft glomerulopathy (AAG) is an unusual glomerular lesion of allografts with endocapillary hypercellularity, markedly enlarged endothelial cells occluding the capillary lumen, and absence…
  • 2016 American Transplant Congress

    Elevated Lung Shunt Fraction as an Independent Predictor of Local Disease Progression and Metastasis in Hepatocellular Carcinoma.

    T. Sandow,1 D. DeVun,1 P. Gulotta,1 H. Bohorquez,2 D. Kirsch.1

    1Department of Radiology, Ochsner Clinic Foundation, New Orleans, LA; 2Department of Transplant Surgery, Ochsner Clinic Foundation, New Orleans, LA.

    Purpose: To establish a relationship between lung shunt fraction (LSF) and local disease progression as well as the development of metastatic disease.Materials and Methods: A…
  • 2016 American Transplant Congress

    Impact of Sarcopenia in Overweight/Obese Recipients on the Outcomes After Adult Living Donor Liver Transplantation.

    A. Hammad,1,2 Y. Hamaguchi,2 S. Okumura,2 A. Kobayashi,2 S. Yagi,2 S. Uemoto,2 T. Kaido.2

    1Department of Surgery, Mansoura University, Mansoura, Dakahliya, Egypt; 2Division of Hepato-Biliary-Pancreatic and Transplant Surgery Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

    Background/purpose: The effects of body composition disturbances on liver transplantation outcomes have recently been in focus. However, the effects of obesity, as well as sarcopenic…
  • 2016 American Transplant Congress

    Fatigue, Pain, and Other Physical Symptoms of Living Liver Donors.

    Z. Butt,1 A. DiMartini,2 Q. Liu,3 M. Simpson,4 A. Smith,3,5 J. Zee,3 B. Gillespie,5 S. Holtzman,6 D. Ladner,1 K. Olthoff,7 R. Fisher,8 S. Hafliger,9 C. Freise,10 M. Mandell,11 M. Dew.2

    1Northwestern U, Chicago; 2U of Pittsburgh, Pittsburgh; 3Arbor Research Collaborative for Health, Ann Arbor; 4Lahey, Burlington; 5U of Michigan, Ann Arbor; 6U of Toronto, Toronto, Canada; 7U of Pennslyvania, Philadelphia; 8Virginia Commonwealth U, Richmond; 9Columbia U, New York; 10U of California at San Francisco, San Francisco; 11U of Colorado, Denver.

    Background: Post-operative pain and fatigue can be significant for some living liver donors (LLD). A better appreciation of these outcomes may inform pre-donation education and…
  • 2016 American Transplant Congress

    Long Term Outcome of Kidney Transplant Recipients Treated with Everolimus: Final 5-Years Results from the Certic Observational Study.

    L. Furian,1 L. Di Maria,2 G. Cappelli,3 M. Carmellini,4 G. Spagnoletti,5 G. Piredda,6 P. Todeschini,7 S. Chiaramonte,8 G. Tisone.9

    1AOU di Padova, Padova, Italy; 2AOU Careggi, Firenze, Italy; 3AOUP di Modena, Modena, Italy; 4AOU Senese, Siena, Italy; 5PU A.Gemelli, Roma, Italy; 6AO G.Brotzu, Cagliari, Italy; 7AOP S.Orsola-Malpighi, Bologna, Italy; 8PO S.Bortolo, Vicenza, Italy; 9Fondazione PU Tor Vergata, Roma, Italy.

    Everolimus is associated with long-term benefits, such as preserving renal function and reducing the incidence of infections, malignancies and major cardiovascular events (MACE). The Certic…
  • 2016 American Transplant Congress

    Long-Term Deterioration of Graft Function (DeKAF) Study: Histologic Interpretation of Cross-sectional vs Prospective Cohorts.

    A. Matas,1 A. Fieberg,1 L. Hunsicker,2 J. Grande,3 For the DeKAF Group.

    1U of MN, Mpls, MN; 2U IA, Iowa City, IA; 3Mayo, Rochester, MN.

    The major aim of the DeKAF study was to define previously unidentified phenotypes resulting in late graft dysfunction and loss (GL). Two cohorts were developed,…
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