2016 American Transplant Congress
The Oldest and Coldest in Kidney Paired Donation: Experience of the National Kidney Registry.
OBJECTIVES: To evaluate renal allograft efficacy and survivability in elderly donors and prolonged cold ischemia time (CIT).METHODS: 1,402 living donor kidney transplants from 02/2008-06/2015 recorded…2016 American Transplant Congress
IgM Donor Specific Antibodies Are Frequently Associated with C1q-binding DnDSA in Renal Transplant Recipients.
Background: Recently, the importance of complement-binding de novo DSA (dnDSA) was documented. We aimed to explore the presence of IgM dnDSA according to C1q dnDSA-binding…2016 American Transplant Congress
Kidney Structural Characteristics as Predictors of Long-Term Kidney Function in Living Kidney Donors.
PurposeKidney structural characteristics may be predictive of long-term living donor outcomes such as a lower estimated Glomerular Filtration Rate (eGFR).MethodsAs part of the Renal and…2016 American Transplant Congress
Common Molecular Features of Human Kidney Transplant Rejection Reflect Mechanistic Sharing Between T Cell-Mediated and Antibody-Mediated Rejection.
1University of Queensland, Brisbane, Australia; 2University of Australia, Edmonton, Canada.
We previously reported the molecular features of human kidney transplant biopsies with T cell-mediated rejection (TCMR) (Am J Transplant 14(11):2565-76) and antibody-mediated rejection (ABMR) (Am…2016 American Transplant Congress
Characteristics of Compatible Pair Participants in Living Donor Kidney Transplant Exchanges.
Renal & Pancreas Transplant Division, Saint Barnabas Medical Center, Livingston, NJ.
Introduction: Compatible pairs of living kidney donors and their intended recipients are being increasingly entered into living donor kidney transplant (LDKT) exchanges. The characteristics of…2016 American Transplant Congress
Recovery of eGFR in Both Donors and Recipients After Living Donor Kidney Transplantation.
MedStar Georgetown Transplant Institute, Washington, DC.
Purpose: LD kidney donation provides a much needed resource for patients with end stage renal disease. Providing adequate renal mass to the recipient (R) is…2016 American Transplant Congress
Is It Worth Risking Lives of Multiple Procurement Surgeons to Save One Life in Extreme Weather Conditions?
Multi Organ Transplantation Unit, London Health Sciences Centre, London, Canada.
Transplant needs highly skilled surgeons and allied medical staff to travel to distant locations on short notices and secure a deceased donor organ that is…2016 American Transplant Congress
IFN-γ and Contact-Dependent Cytotoxicity Are Rate-Limiting for NK Cells in a Model of Antibody-Mediated Chronic Rejection.
BACKGROUND. Natural killer (NK) cells are key components of the innate immune that contribute to acute and chronic graft rejection. After engagement with antibody, NK…2016 American Transplant Congress
ASC-Deficient Dendritic Cells Exhibit Activation Defects and a Reduced Ability to Stimulate Allogeneic T Cells.
Medicine, University of California-San Diego, La Jolla, CA.
Donor dendritic cell (DC) activation causes adaptive immune responses that lead to rejection of transplanted allografts. Accumulating data suggest that inflammasome assembly within interstitial DCs…2016 American Transplant Congress
Bortezomib Impacts Tenascin mRNA in PBMNCs.
Medical University of South Carolina, Charleston.
Tenascin (TNC) is a gene thought to play a role in the binding of receptors and syndecan binding. Syndecans are signal transmembrane proteins that act…
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