ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Time Course of Hepatic Graft Function Improvement After Ledipasivir/Sofosbuvir Treatment in Liver Transplant Recipients with HCV and Fibrosis or Cirrhosis Who Achieved SVR.

    S. Helmke,1 J. O'Leary,2 J. Burton,1 M. Cookson,1 S. Lauriski,1 J. Trotter,2 J. McHutchison,3 G. Everson.1

    1University of Colorado, Aurora, CO; 2Baylor University Medical Center, Dallas, TX; 3Gilead Sciences, Inc., Foster City, CA.

    Background: In SOLAR-1, liver transplant recipients with HCV and either fibrosis or cirrhosis were treated at baseline with ledipasvir/sofosbuvir and ribavirin for 12 or 24…
  • 2016 American Transplant Congress

    Treatment of Hepatitis C Viral Infection with Novel Direct Acting Antivirals in Kidney Transplant Recipients – Single Center Experience.

    K. Hatahet,1 M. Ghanta,1 A. Gillespie,1 I. Lee,1 H. El-Halawany,2 K. Qureshi,2 K. Lau,3 S. Karhadkar,3 A. Di Carlo,3 S. Constantinescu,1 S. Rao.1

    1Nephrology, Temple University, Phildelphia, PA; 2Hepatology, Temple University, Philadelphia, PA; 3Surgery, Temple University, Philadelphia, PA.

    Kidney transplant recipients (KTRs) with Hepatitis C virus infection (HCV+ve) have higher proteinuria and inferior patient and graft survival compared to HCV negative KTRs. Due…
  • 2016 American Transplant Congress

    Acute Operative Complications and 1,5,& 10 Year Outcomes in Living Donors by Type of Live Donor Nephrectomy – UK Cohort Study.

    N. Krishnan,1 L. Bradbury,2 N. Raymond.1

    1Renal & Transplantation, University Hospitals Coventry & Warwickshire NHS Trust, Coventry, United Kingdom; 2Statistics, National Health Service, Organ Donation & Transplant, Bristol, United Kingdom.

    It is important to have a better understanding of the short and long term outcomes and risks of kidney donation. We studied the occurrence of…
  • 2016 American Transplant Congress

    Epitope Load Is Predictive of De Novo Donor Specific Antibodies Occurrence in Renal Transplant Recipients After Conversion from Cyclosporine to Everolimus.

    R. Snanoudj,1 C. Suberbielle,2 N. Kamar,3 E. Cassuto,4 S. Caillard,5 J.-L. Taupin,2 D. Anglicheau,1 C. Legendre,1 A. Hertig,6 E. Rondeau.6

    1Necker Hospital, Paris, France; 2Saint-Louis Hospital, Paris, France; 3Rangueil Hospital, Toulouse, France; 4Pasteur Hospital, Nice, France; 5CHRU, Strasbourg, France; 6Tenon Hospital, Paris, France.

    IntroductionThe degree of HLA compatibility between donor and recipient is an important risk factor of developing de novo DSA, but misjudged by the number of…
  • 2016 American Transplant Congress

    Predonation Prescription Narcotic Use: A Novel Risk Factor for Readmission After Living Donor Nephrectomy.

    K. Lentine,1,7 D. Segev,2,1 D. Axelrod,3 N. Lam,4 A. Garg,5 G. Hess,6 B. Kasiske,1 D. Brennan,8 H. Randall,7 M. Schnitzler.7,1

    1Scientific Registry of Transplant Recipients, Minneapolis; 2Johns Hopkins, Baltimore; 3Dartmouth, Hanover; 4Univ Alberta, Alberta, Canada; 5Western Univ, London, Canada; 6Symphony Health, Pittsburgh; 7Saint Louis Univ, St. Louis.

    Implications of narcotic use in living kidney donor (LKD) candidates for key outcomes, including readmission rates after nephrectomy, are unknown.We integrated 1) national Scientific Registry…
  • 2016 American Transplant Congress

    Mining the Human Proteome for Monitoring Renal Transplant Injury.

    T. Sigdel,1 Y. Gao,2 J. He,2 A. Wang,1 C. Nicora,2 D. Smith,2 W. Qian,2 D. Camp,2 M. Sarwal.1

    1Surgery, University of California-San Francisco, San Francisco; 2Pacific Northwest National Laboratory, Richland.

    The human urinary proteome reflects systemic and inherent renal injury perturbations and can be harnessed to define biomarkers for different kidney transplant injury states. Through…
  • 2016 American Transplant Congress

    Analysis of Broken Chains in Kidney Paired Donation During an 8 Year Period within the National Kidney Registry.

    N. Cowan,1 J. Sinacore,2 H. Gritsch,1 J. Veale.1

    1Department of Urology, University of California - Los Angeles Medical Center, Los Angeles, CA; 2National Kidney Registry, Babylon, NY.

    Purpose: Chain transplantation in kidney paired donation (KPD) offers the ability to facilitate multiple kidney transplants between incompatible pairs using a non-directed donor (NDD) to…
  • 2016 American Transplant Congress

    Hospitalization and Living Donor Kidney Transplantation Among Waitlisted End Stage Renal Disease Patients in the US.

    K. Newman,1,2 A. Adams,2 S. Pastan,2 R. Lynch,2 R. Zhang,1 R. Patzer.1,2

    1Emory University Rollins School of Public Health, Atlanta, GA; 2Emory University School of Medicine, Atlanta, GA.

    Background: For End Stage Renal Disease Patients (ESRD) waitlisted for a deceased donor kidney, living donor kidney transplantation (LDKT) could allow for earlier transplantation and…
  • 2016 American Transplant Congress

    Racial Differences Amongst Infants Undergoing Intestine Transplants.

    K. Khan, C. Desai, S. Kaufman, R. Girlanda, J. Hawksworth, A. Kroemer, T. Fishbein, C. Matsumoto.

    Transplant Institute, MedStar Geogetown University Hospital, Washington, DC.

    BackgroundIt is known that the demographics of the United States are changing because of immigration and increased birth rates in non-white populations. Here we examine…
  • 2016 American Transplant Congress

    Late Renal Xenograft Failure Is Antibody-Mediated: Description of the Longest-Reported Survival in Pig-to-Primate Renal Xenotransplantation.

    L. Higginbotham,1 S. Kim,1 D. Mathews,1 A. Stephenson,1 C. Breeden,1 C. Larsen,1 M. Ford,1 K. Newell,1 A. Tector,2 A. Adams.1

    1Emory Transplant Center, Emory University Hospital, Atlanta, GA; 2Indiana University School of Medicine, Indianapolis, IN.

    Introduction. Xenotransplantation has the potential to alleviate the organ supply shortage, yet pig-to-primate renal xenotransplant has met limited success due to natural preformed anti-pig antibody.…
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