Am J Transplant, Volume 16, Suppl 3 Archives - Page 138 of 180 - ATC Abstracts

2016 American Transplant Congress
Torque Teno Virus – Inverse Association with Late Silent Antibody Mediated Kidney Allograft Rejection.
G. Bond,¹ M. Schiemann,¹ F. Eskandary,¹ H. Herkner,² E. Puchhammer,³ R. Oberbauer,¹ G. Böhmig.¹
¹Nephrology and Dialysis, Medical University of Vienna, Vienna, Austria; ²Emergency Medicine, Medical University of Vienna, Vienna, Austria; ³Virology, Medical University of Vienna, Vienna, Austria.
Clinical Problem and hypothesis: Antibody mediated rejection (ABMR) is a cardinal cause of late graft failure after kidney transplantation (KTX). A promising predictive diagnostic tool…
2016 American Transplant Congress
Do Highly Sensitized Recipients Benefit from the Immunological Advantages of Zero Mismatched (0MM) Deceased Donors (DD) Kidney Allografts?
N. Elfadawy,¹ S. Flechner,² J. Schold.²
¹Internal Medicine, Case Western Reserve University, Cleveland, OH; ²Glickman urological and kidney institute, Cleveland Clinic, Cleveland, OH.
HLA 0MM DD transplants have superior outcomes compared with outcomes for grafts with ≥1 HLA mismatches, but when past reports analyzed 0MM outcomes in DD,…
2016 American Transplant Congress
Gut Dysbiosis and Metabolic Disorders in Kidney Transplant Recipients.
M. Lecronier,¹ P. Tashk,¹ J. Aron-Wisnewsky,^2,3,4 E. Denamur,¹ O. Tenaillon,¹ B. Barrou,^4,5 J. Tourret.^1,4,5
¹IAME, UMR 1137, INSERM, Paris, France; ²Institute of Cardiometabolism and Nutrition, ICAN, Service de Nutrition, GH Pitié-Salpêtrière Charles Foix, AP-HP, Paris, France; ³UMR_S U1166, équipe NutriOmics, INSERM, Paris, France; ⁴Sorbonne Universités, Université Pierre et Marie Curie, Paris, France; ⁵AP-HP, Département d'Urologie, Néphrologie et Transplantation, GH Pitié-Salpêtrière Charles Foix, Paris, France.
IntroductionGut microbiota modifications (dysbiosis) have been observed in obese and/or diabetic patients. Kidney transplant recipients (KTR) are particularly exposed to the development of metabolic disorders,…
2016 American Transplant Congress
Serum Inflammatory Biomarkers in Kidney Transplant Recipients and Renal Donors.
J. Ramirez,¹ E. Cuevas,¹ J. Furuzawa,² L. Morales-Buenrostro,³ M. Lopez-Cervantes,² J. Alberu.¹
¹Transplantation, Inst Nal Ciencia Medicas y Nutricion SZ, Mexico City, Mexico; ²Immunology, Inst Nal Ciencia Medicas y Nutricion SZ, Mexico City, Mexico; ³Nephrology, Inst Nal Ciencia Medicas y Nutricion SZ, Mexico City, Mexico; ⁴Medicine School, UNAM, Mexico City, Mexico.
Kidney transplant recipients (KTR) have an increased risk for cardiovascular events, graft failure, and death. It is unknown whether serum inflammatory biomarkers correlate with eGFR…
2016 American Transplant Congress
Delayed Graft Function Is an Independent Risk Factor for Renal Allograft Rejection.
T. Dienemann, S. Weber, J. Jacobi, K.-U. Eckardt, A. Weidemann.
Nephrology and Hypertension, Universitaetsklinikum Erlangen, Universiaet Erlangen Nuernberg, Erlangen, Germany.
Background: Numerous risk factors for delayed graft function (DGF) after kidney transplantation (KTx) have been identified. However the effect of DGF as an independent risk…
2016 American Transplant Congress
High Concentrations of CXCL9 and CXCL10 Chemokines but Not CXCL8 (IL-8), IL-6, TNF-a or IFN-g in Biopsy Tissue Are Associated with Pathological Staging of Rejection After Kidney Transplantation.
C. Falk,¹ C. Neudörfl,¹ K. Daemen,¹ J. Keil,¹ F. Lehner,² H. Haller,³ J. Schmitz,⁴ C. Blume,⁵ J.-H. Bräsen.⁴
¹Institute of Transplant Immunology, IFB-Tx, Hannover Medical School, Hannover, Germany; ²Department of Abdominal and Transplantation Surgery, Hannover Medical School, Hannover, Deutschland, Germany; ³Department of Nephrology and Hypertension, Hannover Medical School, Hannover, Deutschland, Germany; ⁴Institute of Pathology, Hannover Medical School, Hannover, Deutschland, Germany; ⁵Institute of Technical Chemistry, Leibniz University Hannover, Hannover, Deutschland, Germany.
Background: Extensive expression profiling efforts of biopsy tissue after kidney transplantation indicate that rejection, especially antibody-mediated rejection (AMR) can be defined by distinct signatures. Thus,…
2016 American Transplant Congress
ESAT-6 Inhibits Donor-Specific Memory CD8+ T Cell Generation and Alloimmune Responses.
Z. Dai,¹ H. Dai.²
¹Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, China; ²University of Pittsburgh, Pittsburgh.
Inducing long-term transplant survival or tolerance without continuous global immunosuppression is a highly desired goal in organ transplantation because conventional immunosuppressive drugs usually cause severe…
2016 American Transplant Congress
iNKT Cell Activation Under Co-Stimulatory Blockade Establishes Mixed Chimerism Through Thymic Regulatory T Cell Activation.
T. Hirai,¹ Y. Ishii,² R. Ishii,¹ S. Miyairi,¹ M. Ikemiyagi,¹ M. Okumi,¹ K. Tanabe.¹
¹Department of Urology, Tokyo Women's Medical University, Shinjuku, Tokyo, Japan; ²Laboratory for Vaccine Design, RIKEN-IMS, Yokohama, Kanagawa, Japan.
Background: Invariant natural killer T (iNKT) cells have recently garnered considerable attention for their potential to induce regulatory T cells (Tregs). We previously reported a…
2016 American Transplant Congress
Neighborhood Socioeconomic Characteristics Influence Access to Kidney Transplantation Independently of Individual Socioeconomic Status.
J. Adler, J. Markmann, D. Chang, H. Yeh.
Surgery, Massachusetts General Hospital, Boston, MA.
INTRODUCTION: Ensuring fair and equitable access to kidney transplantation (ATT) is of paramount importance. Socioeconomic disadvantage is associated with worse access to healthcare. Understanding the…
2016 American Transplant Congress
Racial Disparities in the Evaluation for Liver Transplantation.
M. Jesse, E. Goldstein, N. Rebhan, C.-X. Ho, T. Macaulay, M. Bebanic, L. Shkokani, D. Moonka, M. Abouljoud, A. Yoshida.
Transplant Institute, Henry Ford Health System, Detroit, MI.
The majority of research on disparities in liver transplantation is on patients listed for transplant in the OPTN/UNOS database, not patients in the evaluation process…