2016 American Transplant Congress
The Influence of Rising Lab MELD on Vascular Invasion in HCC.
Liver Transplant & HPB Surgery, Weill Cornell Medical College, NY, NY.
Background Vascular invasion (VI) is one of the most important predictors of HCC recurrence. Although attempts to identify predictors of VI have been made, datasets…2016 American Transplant Congress
Anti-Angiotensin II Type 1 Receptor Antibody Reduction with Proteasome Inhibitor-Based Desensitization.
University of Cincinnati, Cincinnati.
Background. Desensitization results have largely focused on effects on anti-HLA antibody (HLA-Ab) and anti-ABO antibody levels. Anti-angiotensin II type 1 receptor antibody (AT1R-Ab) has recently…2016 American Transplant Congress
Normothermic Ex Vivo Liver Perfusion (NEVLP) Using Steen Solution as Preservation Technique for Liver Transplantation-First Clinical Results.
Surgery, Toronto General Hospital, Toronto, Canada.
The European trial investigating NEVLP as preservation technique for liver transplantation uses Gelafusine, a non-FDA approved bovine derived gelatin-based perfusion solution. In contrast, we report…2016 American Transplant Congress
Assessment of Chikungunya IgM Prevalence Among Deceased Organ and Tissue Donors Using Two Enzyme Immunoassay (EIA) Kits.
Viracor-IBT Laboratories, Los Angeles, CA.
Study Purpose: The emergence of Chikunungya virus (ChikV) infection in the western hemisphere has raised concerns of donor-derived transmission. We assessed the prevalence of recent…2016 American Transplant Congress
Association of Cytomegalovirus-Specific T Cell-Mediated Immunity with the Risk of CMV Infection Occurrence in Kidney Transplant Recipients.
Introduction CMV remains the significant cause of morbidity in transplant recipients. Despite universal prophylaxis, late CMV infection occurs in high proportion of kidney transplant recipients.…2016 American Transplant Congress
Foxp3 Controls Oxidative Phosphorylation in Regulatory T Cells.
Current immunosuppressive therapies are limited by non-specificity and toxicities, and new pharmacologic approaches to immunosuppressive therapies are needed. Many T cell subsets have distinct metabolic…2016 American Transplant Congress
NK Cells Are Required in B-Cell Dependent, Antibody Mediated Islet Transplant Tolerance.
Dept of Surgery, Transplant Surgery Division, Massachusetts General Hospital, Boston, MA.
Immunologic tolerance to islets has been achieved in various rodent models using antibodies directed at CD45RB and Tim-1. We have shown that this tolerance mechanism…2016 American Transplant Congress
Tracking Endogenous B Cells Recognizing Allogeneic MHC Class II in Mice.
Clinical data suggest that donor-specific antibody (DSA)-mediated rejection is currently the leading cause of kidney allograft failure, with anti-donor Class II Abs tending to be…2016 American Transplant Congress
Profiling Metabolic Differences Between Graft- vs. Pathogen-Elicited CD8+ T Cell Responses.
The challenge of immune modulation in transplantation is to inhibit pathologic alloreactivity while minimizing off-target toxicities and preserving protective immunity. Data have emerged demonstrating the…2016 American Transplant Congress
Factors and Outcomes Associated with Daptomycin Non-Susceptible Enterococcal Infections in Solid Organ Transplant Recipients.
Background: Daptomycin non-susceptible enterococcal (DNSE) infections are associated with poor outcomes. Information regarding factors and outcomes of DNSE in solid organ transplant (SOT) recipients (SOTR)…
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