Am J Transplant, Volume 16, Suppl 3 Archives - Page 133 of 180 - ATC Abstracts

2016 American Transplant Congress
Effect of Inflammation on Concentration of Intracellular Tacrolimus.
E. Bae,¹ S. Yang,² S. Han,¹ J.-Y. Park,¹ H. Lee,¹ Y. Kim.¹
¹Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea; ²Kidney Research Institute, Seoul National University, Seoul, Republic of Korea.
Background: The use of calcineurin inhibitors improved the outcome for transplant recipients. However, acute rejection (AR) and infection remained still an unsolved problem. We evaluated…
2016 American Transplant Congress
Tacrolimus Levels in Patients Treated with Direct Acting Antivirals Post-Transplant.
J. Wiegel, T. Egbuka.
Pharmacy, Oregon Health & Science University, Portland, OR.
Purpose: To determine if treatment of recurrent hepatitis C virus (HCV) post-liver transplant with the direct-acting antivirals (DAAs) sofosbuvir, simeprevir, and ledipasvir (in combination and/or…
2016 American Transplant Congress
Initial Experience with the Bacterial Enzyme IdeS® (IgG Endopeptidase) for Desensitization of Highly-HLA Sensitized (HS) Patients.
S. Jordan,¹ J. Choi,¹ X. Zhang,¹ M. Haas,² A. Peng,¹ J. Kahwaji,¹ R. Villicana,¹ A. Vo.¹
¹Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA; ²Pathology, Cedars-Sinai Medical Center, Los Angeles, CA.
Introduction: The IgG degrading enzyme derived from Streptococcus pyogenes (IdeS®) is a 35k-Da cysteine protease that cleaves human IgG molecules at the lower hinge region…
2016 American Transplant Congress
Porcine Islets Engineered to Display SA-FasL Protein on Their Surface Induce Tolerance in Mice Following Transplantation into the Liver or Under the Kidney Capsule.
H. Zhao,¹ K. Woodward,¹ H. Shirwan,¹ M. Graham,² B. Hering,² E. Yolcu.¹
¹Institute for Cellular Therapeutics and Department of Microbiology and Immunology, University of Louisville, Louisville, KY; ²Schulze Diabetes Institute and Department of Surgery, University of Minnesota, Minneapolis, MN.
Introduction: We have recently demonstrated that allogeneic islets engineered to transiently display on their surface a novel form of FasL protein chimeric with streptavidin (SA-FasL)…
2016 American Transplant Congress
Generation of Naïve Donor-Derived Lymphocytes from Graft-Resident Lymphoid Progenitors After Human Intestinal Transplantation.
J. Fu, J. Zuber, B. Shonts, S. Lau, A. Obradovic, T. Savage, M. Simpson, S. Yang, Y. Shen, M. Martinez, A. Griesemer, T. Kato, M. Sykes.
Columbia University, New York.
Multivisceral transplantation (MVTx) is associated with a lower rate of severe graft rejection than isolated intestinal transplantation (iITx). We recently demonstrated that mixed T cell…
2016 American Transplant Congress
Prospective Randomized Controlled Study Evaluating the Impact of an Electronic Feedback System on Medication Adherence in Solid Organ Transplantation.
M. Lockwood, L. Potter, B. Kane, L. Lourenco, A. Bozdin, J. Millis.
University of Chicago Transplant Center, University of Chicago, Chicago.
Purpose: To evaluate the impact of and electronic feedback system (EFS), SIMpill Medication Adherence System®, on medication adherence in patients who have received a solid…
2016 American Transplant Congress
Living Donor Liver Transplant Has Similar Outcome to Deceased Donor Liver Transplant for MELD > 25.
M. Al Sebayel,¹ F. Abaalkhail,^1,2 M. Shoukri,¹ H. Albahili,^1,2 S. Alabbad,¹ W. AlHamoudi,^1,2,3 H. Albeshbeshy,¹ H. Elsiesy.^1,2
¹Liver Transplantation, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia; ²Alfaisal University, Riyadh, Saudi Arabia; ³Department of Gastroenterology, King Saud University, Riyadh, Saudi Arabia.
Background and Aims: Model for End-Stage Liver Disease (MELD) score is universally used to prioritize patients on the liver transplant (LT) waiting list. There has…
2016 American Transplant Congress
The Impact of One Year Individual or Dual Organ Rejection in Simultaneous Pancreas-Kidney Transplant on Kidney Graft Survival – A UNOS Registry Analysis 2000-2013.
I. Moinuddin,¹ T. Taber,¹ M. Yaqub,¹ O. Adebiyi,¹ M. Mujtaba,¹ J. Chen,² M. Goble,² D. Mishler,¹ J. Fridell,² A. Sharfuddin.¹
¹Medicine/Nephrology, Indiana University, Indianapolis; ²Surgery/Transplant, Indiana University, Indianapolis.
Background: Early Rejection of either organ in Simultaneous Pancreas-Kidney transplants (SPK) is common within the first 1 year. We studied the impact of within 1…
2016 American Transplant Congress
Acute Inflammation, Chronic Damage and Renal Dysfunction in Renal Transplant Recipients with Delayed Graft Function (DGF).
A. Cherukuri, R. Mehta, P. Sood, P. Randhawa, A. Tevar, S. Hariharan.
UPMC, Pittsburgh.
Analysis of DGF and clinical outcomes in relation to progressive histological changes is not well reported. In this prospective longitudinal study, patients with DGF were…
2016 American Transplant Congress
Non-adherence is associated with increased risk of rejection and graft loss.
R. Pullalarevu,¹ D. Taber,² A. Chokkalingam,² R. Browning,¹ M. Kamel,¹ M. Salazar,¹ T. Srinivas,¹ M. Posadas Salas.¹
¹Medicine, MUSC, Charleston, SC; ²Surgery, MUSC, Charleston, SC.
Non-adherence is common among kidney transplant recipients. However, data on the impact of appointment and medication non-adherence on kidney transplant outcomes are scarce. This study…