ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    The Impact of Early Acute Rejection and Delayed Graft Function on Graft Outcomes at Six Months in Adult Deceased Donor Kidney Recipients.

    D. Keith, G. Vranic, A. Nishio Lucar.

    University of Virginia, Charlottesville, VA.

    Graft function as determined by GFR is an important predictor of long-term graft and patient survival after deceased donor kidney transplantation. KDPI is an important…
  • 2016 American Transplant Congress

    De Novo Anti-HLA DSA Characteristics and Subclinical Antibody Mediated Kidney Allograft Injuries.

    T. Yamamoto, Y. Watarai, A. Takeda, M. Okada, M. Tsujita, T. Hiramitsu, N. Goto, S. Narumi, K. Morozumi, K. Uchida, T. Kobayashi.

    Nagoya daini red cross hospital, Nagoya, Japan.

    Background It has been reported that de novo donor-specific HLA antibody (dn DSA) production is associated with chronic antibody-mediated rejection (CAMR) which leads to poor…
  • 2016 American Transplant Congress

    Motivation and Stress Associated with Non-Directed Kidney Donation.

    J. Wiseman,1 D. Berglund,1 C. Jacobs,1 D. Larson,1 C. Garvey,1 M. Vogues, S. Rein,1 O. Sanchez,1 C. Radecki Breitkopf,2 H. Ibrahim,1 A. Matas.1

    1U of MN, Mpls; 2Mayo Clinic, Rochester.

    Background: Nondirected kidney donors (NDDs) are unique in that they have the risks of nephrectomy but often do not have the benefit of seeing the…
  • 2016 American Transplant Congress

    VDJ Immune Repertoire Sequencing Predicts Patients at Risk of Alloimmune Injury.

    M. Sirota,1 T. Sigdel,1 S. Boyd,2 A. Fire,2 M. Sarwal.1

    1Surgery and Bioinformatics, UCSF, San Francisco, CA; 2Genetics, Stanford University, Palo Alto, CA.

    Background: The complex repertoire of immune receptors generated by B cells enables allo-recognition in the context of transplantation across HLA barriers, and is a major…
  • 2016 American Transplant Congress

    A Kidney Paired Donation Standard Acquisition Charge Pilot Program.

    M. Rees,1 L. Reece,2 S. Rees,2 B. Crandall,2 A. Leichtman.4

    1UT, Toledo; 2APKD, Perrysburg; 3Arbor Res, Ann Arbor.

    Background/Purpose: A national non-profit Kidney Paired Dontion (KPD) organization undertook a demonstration project to redesign payment for KPD transplants with a payment model similar to…
  • 2016 American Transplant Congress

    The Effect of Donor-Recipient Relationship on the Immunologic Outcome in Living Kidney Transplantation.

    D. Khadzhynov, F. Halleck, L. Lehner, M. Duerr, J. Waiser, K. Budde, O. Staeck.

    Nephrology, Charite Campus Mitte, Berlin, Germany.

    Background. Presensitization and degree of HLA-matching influences immunologic outcome and kidney graft survival. Thus the donor-recipient relationship may influence incidence of immunologic events and outcome…
  • 2016 American Transplant Congress

    Arterial Hypertension After Renal Transplantation in Pediatric Patients: An Analysis of CERTAIN Registry.

    R. Sugianto,1 E. Wühl,2 B. Schmidt,1 K. Krupka,2 B. Höcker,2 B. Tönshoff,2 A. Melk.1

    1Children's Hospital, Hannover Medical School, Hanover, Germany; 2Division of Pediatric Nephrology, University of Heidelberg, Heidelberg, Germany.

    BackgroundOur study aimed to describe the prevalence of hypertension & blood pressure (BP) control as well as influencing factors in pediatric renal transplant patients.MethodCasual BP…
  • 2016 American Transplant Congress

    Cross-Talk Between TLR and BCR Pathways Induces CNI-Resistance in B-Cells Responding to Blood Group A-Antigens: A Novel Paradigm for Treatment with TLR-Inhibitor for CNI-Resistant AMR.

    H. Sakai, Y. Tanaka, H. Ohdan.

    Hiroshima University, Hiroshima, Japan.

    [Aim] Bacterial infections after ABO-incompatible transplantation are associated with refractory antibody (Ab)-mediated rejection (AMR). We demonstrated that bacterial pathogens provoke B cells, responding to human…
  • 2016 American Transplant Congress

    IL2 and IL-15 Rescue TEMRA CD8 T Cells from Mitochondrial Dysfunction Associated Senescence Through a p38MAPK Dependent Pathway and Foster Their Pathogenic Potential.

    G. Tilly,1,2 M. Yap,1,2 M. Giral,1,2,3 C. Pecqueur,4 S. Brouard,1,3 N. Degauque.1,3

    1UMR1064, INSERM, Nantes, France; 2Université de Nantes, Nantes, France; 3ITUN, CHU de Nantes, Nantes, France; 4UMR892, INSERM, Nantes, France.

    Background & Study Aim. We recently showed that an accumulation of highly differentiated TEMRA CD8 T cells in kidney transplant recipients with a stable graft…
  • 2016 American Transplant Congress

    In Vitro Induction of T Regulatory Cells by Multipotent Adult Progenitor Cells.

    S. Stubblefield, N. Williams, A. Ting.

    Regenerative Medicine, Athersys, Inc, Cleveland, OH.

    There is increasing evidence that transplanted adult stemcells remain undifferentiated and often are cleared after a short time.However, these short-lived stem cells still promote recovery…
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