Am J Transplant, Volume 16, Suppl 3 Archives - Page 113 of 180 - ATC Abstracts

2016 American Transplant Congress
Effect of Adipose Tissue-Derived Mesenchymal Stem Cells in a Rat Model of Chronic Renal Allograft Rejection.
R. Pepineli, F. Silva, P. Gouveia, G. Tavora, S. Gomes, I. Noronha.
Renal Division, University of Sao Paulo, Sao Paulo, Brazil.
Adipose tissue-derived mesenchymal stem cells (ASC) may represent a new strategy to prevent allograft rejection after kidney transplantation due to its immunomodulatory properties. In the…
2016 American Transplant Congress
HLA Identical Renal Transplant Tolerance Using Donor Hematopoietic Stems Cells (DHSC): Role of Immunoregulation.
J. Leventhal,¹ J. Mathew,¹ D. Salomon,² S. Kurian,² J. Friedewald,¹ L. Gallon,¹ X. Huang,¹ A. Tambur,¹ Y. Kanwar,¹ J. Charette,¹ M. Abecassis,¹ J. Miller.¹
¹Surgery - Comprehensive Transplant Center, Northwestern University, Chicago, IL; ²The Scripps Research Institute, La Jolla, CA.
Purpose: Despite being a “perfect match”, HLA-identical kidney transplants (HLA-Id KTx) are rejected without sufficient immunosuppression (IS), and hence can also benefit from tolerance induction.…
2016 American Transplant Congress
Short-Term Post-Donation Renal Function in Living Kidney Donors.
L. Fahmy, A. Massie, A. Muzaale, S. Sandal, E. Chow, D. Segev.
JHU, Baltimore.
Previous single-center studies of post-donation estimated glomerular filtration rate (eGFR) in living kidney donors were limited by small sample size and lack of generalizability. The…
2016 American Transplant Congress
Utilization and Post-Transplant Outcomes Associated with Hepatitis C+ Donor Kidneys in the Advent of Direct-Acting Antivirals.
M. Bowring, L. Kucirka, A. Massie, X. Luo, M. Sulkowski, D. Segev, C. Durand.
JHU, Baltimore.
The introduction of interferon-free direct-acting antivirals(DAAs) in December 2013 dramatically improved outcomes for individuals with Hepatitis C. The impacts of these therapies on utilization and…
2016 American Transplant Congress
C1-Inhibitor in Acute Antibody-Mediated Rejection Non-Responsive to Conventional Therapy in Kidney Transplant Recipients: A Pilot Study.
C. Lefaucheur,¹ D. Viglietti,¹ C. Gosset,¹ A. Loupy,² A. Zeevi,³ D. Glotz.¹
¹Saint-Louis Hospital, Paris, France; ²Necker Hospital, Paris, France; ³University of Pittsburgh Medical Center, Pittsburgh.
The use of complement inhibitors in the treatment of acute antibody-mediated rejection (AMR) has not been thoroughly evaluated. We performed a prospective, single-arm, pilot study…
2016 American Transplant Congress
Improved Health Related Quality of Life Also in Older Recipients Following Kidney Transplantation.
K. Lønning,¹ K. Heldal,^2,3 T. Bernklev,^2,3 M. Andersen,^1,4 A. Hartmann,^1,3 N. Von der Lippe,³ A. Reisæter,¹ K. Midtvedt.¹
¹Department of Organ Transplantation, Oslo University Hospital, Oslo, Norway; ²Clinic of Internal Medicine, Telemark Hospital, Skien, Norway; ³Institute of Clinical Medicine, University of Oslo, Oslo, Norway; ⁴Department of Health Sciences, University of Oslo, Oslo, Norway.
Background: There is a lack of knowledge regarding elderly patients with end stage renal disease (ESRD) and health related quality of life (HRQOL) after KTX.…
2016 American Transplant Congress
Early Steroid Withdrawal in African American Kidney Transplant Recipients: A Propensity Score Matching Analysis.
D. Taber, M. Gebregziabher, T. Srinivas, K. Chavin, P. Baliga, L. Egede.
MUSC, Charleston, SC.
Objective: The aim of this study was to assess the safety of steroid withdrawal in African American (AA) kidney transplant (KTX) recipients.Methods: Longitudinal cohort study…
2016 American Transplant Congress
Dynamics of Delayed Graft Function-Associated Risk in Deceased Donor Kidney Transplantation.
C. Liao, A. Massie, S. Bae, A. Muzaale, D. Segev.
JHU, Baltimore.
The long-term implications of delayed graft function (DGF) remain controversial. Moreover, non-proportional hazards of DGF have been reported in previous studies, which suggested that its…
2016 American Transplant Congress
Relationship Between Mean Fluorescence Intensity and C1q/C3d-Fixing Capacities of Anti-HLA Antibodies.
G. Claisse,¹ L. Absi,² E. Alamartine,¹ N. Maillard,¹ C. Mariat.¹
¹Centre Hospitalier Universitaire - Hôpital Nord, Saint-Etienne, France; ²Laboratoire EFS Loire-Auvergne, Saint-Etienne, France.
The capacity of anti-HLA antibodies (Abs) to activate complement is thought to be an informative property susceptible to facilitate outcome prediction. Two different tests, C1q-…
2016 American Transplant Congress
DSA After Transplant Increases Risk of Renal Allograft Failure Independent of Concurrent Biopsy Results: The DEKAF Study Data.
J. Cecka,¹ J. Grande,² F. Cosio,² R. Leduc,³ The DeKAF Study Group.
¹UCLA Immunogenetics Center Department of Pathology, University of California-Los Angeles, Los Angeles, CA; ²Department of Lab Medicine & Pathology, Mayo Clinic College of Medicine, Rochester, MN; ³Department of Biostatistiscs, University of Minnesota School of Public Health, Minneapolis, MN.
Donor-specific HLA antibodies (DSA) are a major cause of renal allograft dysfunction and loss following transplant. The presence of DSA, with or without C4d deposition,…