2016 American Transplant Congress
Antibody Mediated Rejection and Mixed Acute Rejection: Long Term Results and Predictive Factors for Graft Loss Following Proteasome Inhibitor Therapy.
1U of Cincinnati, Cincinnati; 2The Christ Hospital, Cincinnati.
Purpose: Proteasome inhibitor (PI) therapy has been increasingly used to treated antibody mediated rejection (AMR) and mixed acute rejection (MAR). The purpose of this study…2016 American Transplant Congress
A Non-Invasive Blood Transcriptional Assay, Ksort, Monitors Alloimmune Response in the Sailor Randomized Multicenter Trial.
Non-invasive diagnosis and prediction of acute rejection (AR) is a critical unmet need. A In a randomized multicenter trial of 222 renal transplant recipients a…2016 American Transplant Congress
Financial Cost of Cold Ischemia Time in Kidney Transplantation.
PURPOSE: A new kidney allocation system (KAS) was implemented in December 2014 using the kidney donor profile index (KDPI), which prioritizes historically-disadvantaged populations. While KAS…2016 American Transplant Congress
Lessons Learned Transplanting High KDPI Kidneys Over a Decade: Improvements in Graft Survival Stem from Lower Rates of Early Graft Loss.
Purpose. The Kidney Donor Profile Index (KDPI) recently replaced SCD/ECD designations, to provide transplant centers a more precise estimate of predicted graft survival, with the…2016 American Transplant Congress
Outcomes of EVAR in Kidney Transplant Recipients: Results form a National Quality Initiative.
BACKGROUND:Contrast-induced nephropathy following endovascular aortic aneurysm repair (EVAR) in renal transplant patients can have devastating consequences. We describe outcomes within a national cohort of kidney…2016 American Transplant Congress
Subnormothermic Machine Perfusion (SNMP) of Liver Allografts with a Novel Hemoglobin-Based Oxygen Carrier (HBOC) Increases β-Oxidation of Fatty Acids and Decreases Lipid Peroxidation (LP).
University of Pittsburgh, Pittsburgh.
Introduction: There is limited information about the lipid metabolic profile during liver allograft preservation. LP remains a major component of ischemia-reperfusion injuries (IRIs). The aim…2016 American Transplant Congress
Molecular Diagnosis of Antibody-Mediated Rejection in Routine Formalin-Fixed Paraffin-Embedded Nonhuman Primate Renal Allograft Biopsies.
Background: In 2013, the Banff classification proposed molecular testing as an adjunct for the diagnosis of antibody-mediated rejection (ABMR) in renal allografts. We analyzed whether…2016 American Transplant Congress
Characterization of T Regulatory Type 1 (Tr1) Cells in Naïve and Transplanted Non-Human Primates.
Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA.
BackgroundT regulatory Type 1 (Tr1) cells are peripheral CD4+FoxP3- regulatory T cells expressing CD49b and LAG-3 in mice and humans. Mouse Tr1 cells inhibit antigen-presenting…2016 American Transplant Congress
Prospective Long-Term Analysis of B- and Plasma Cell Subsets in Renal Transplant Patients After Combined Treatment with Rituximab and Bortezomib in Antibody Mediated Rejection.
Nephrology, Charité Berlin, Berlin, Germany.
Treatment of antibody-mediated rejection (AMR) in renal transplant (Tx) patients (pts) is still challenging and long-term outcome remain poor. Our present treatment strategy with bortezomib…2016 American Transplant Congress
The Impact of Different Immunosuppressive Protocols on Early and Long Term Outcomes After Kidney and Pancreas Transplantation.
Surgery/Transplant, The Ohio State University Wexner Medical Center, Columbus, OH.
Between January 1990 and December 2014, 800 combined kidney pancreas transplant procedures were performed at The Ohio State University. The immunosuppressive protocols have changed significantly…
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