Am J Transplant, Volume 16, Suppl 3 Archives - Page 105 of 180 - ATC Abstracts

2016 American Transplant Congress
Th17 Development Is Critical for Airway Epithelial Injury After Transplantation.
J. Xu, Y. Zhang, L. Wang, X. Li, R. Chen, R. Zhang, Y. Ding.
Department of Immunology, Capital Medical University, Beijing, China.
Background: Development of obliterative bronchiolitis (OB) is the biggest obstacle that limits long-term allograft survival and clinical application of lung transplantation, and the precise mechanisms…
2016 American Transplant Congress
Heat Shock Protein 90 Inhibitor 17DMAG Is a Potential New Therapeutic Agent Against Acute Allograft Rejection.
T. Maehana,¹ T. Tanaka,¹ H. Kitamura,² N. Masumori.¹
¹Urology, Sapporo Medical University School of Medicine, Sapporo, Japan; ²Urology, Graduate School of Medicine and Pharmaceutical Sciences for Research, University of Toyama, Toyama, Japan.
Purpose: We have previously demonstrated that Heat shock protein 90 (HSP90) plays a role in the development of acute rejection (AR) in organ transplantation. To…
2016 American Transplant Congress
Treg-Rich Organized Lymphoid Structures (TOLS) in Spontaneously Accepted Mouse Kidney Allografts.
C. Yang,¹ E. Farkash,² D. Ndishabandi,¹ R. White,¹ B. Jiang,¹ I. Aljabban,¹ P. Russell,¹ J. Madsen,¹ R. Colvin,¹ A. Alessandrini.¹
¹Center for Transplantation Sciences, Dept. of Surgery, Dept. of Pathology, Massachusetts General Hospital, Boston, MA; ²University of Michigan School of Medicine, Ann Arbor, MI.
Background: In many MHC mismatched strain combinations (e.g., DBA/2 to B6) kidney allografts are spontaneously accepted without immunosuppression. This tolerance is regulatory, initially dependent Foxp3+…
2016 American Transplant Congress
African Americans and Organ Donation: Where Do We Go After Moving from the Bottom to the Top?
C. Callender,¹ N. Koizumi,² P. Miles,³ J. Melancon.³
¹Department of Surgery, Howard University, Washington, DC; ²School of Policy, Government and Intl Affairs, George Mason University, Arlington, VA; ³Transplant Institute, George Washington University Hospital, Washington, DC.
PURPOSEThe purpose is to increase organ donation in all ethnic groupsMETHODSThe methodology was based upon the D.C. Organ Donor Program (1982-88) and the Dow Take…
2016 American Transplant Congress
Rurality Status Does Not Affect Kidney Transplant (KTP) Rates Among Veterans Compared to Medicare, Medicaid, and Private Insurance (PrivIns) Beneficiaries.
R. Kalil,^1,2 C. Franciscus,² A. O'Shea.^1,2
¹Internal Medicine/Nephrology, University of Iowa, Iowa City; ²Comprehensive Access and Delivery Research Evaluation (CADRE), Iowa City VAMC, Iowa City.
Background: A larger proportion of Veterans live in rural areas compared to non-Veterans. It is unknown whether rural status affects KTP rates among Veterans.Methods: Study…
2016 American Transplant Congress
Pediatric Critical Care Education Impacts Pediatric Organ Donation.
D. Lebovitz,¹ T. Nakagawa,² C. Wright.³
¹Critical Care, Akron Children's Hospital, Akron, OH; ²Pediatrics, Wake Forest School of Medicine, Wake Forest, NC; ³Lifelink of Florida, Tampa, FL.
Objective: Pediatric donation impacts the disparity between organs needed and organs available for transplantation. We evaluated if a regional educational effort on pediatric donation for…
2016 American Transplant Congress
Deceased Organ Donors with Zero Organs Transplanted: Why and How Can We Improve?
P. Lange,¹ S. Rudich,¹ N. Obaseki,¹ J. Punch.²
¹Medical Division, Gift of Life Michigan, Ann Arbor, MI; ²Surgery, University of Michigan, Ann Arbor, MI.
Organ recovery professionals and donor hospitals are under intense pressure to go to whatever lengths necessary to provide transplantable organs. However, such a mentality can…
2016 American Transplant Congress
A Randomized-Controlled Trial Comparing the Efficacy of CYP3A5 Genotype-Based with Bodyweight-Based Tacrolimus Dosing After Living Donor Kidney Transplantation.
N. Shuker,^1,2 R. Bouamar,² R. van Schaik,³ M. Clahsen -van Groningen,⁴ J. Damman,⁵ C. Baan,¹ J. van de Wetering,¹ A. Rowshani,¹ W. Weimar,¹ T. van Gelder,^1,2 D. Hesselink.¹
¹Internal Medicine, Erasmus Medical Centre, Rotterdam, Netherlands; ²Hospital Pharmacy, Erasmus Medical Centre, Rotterdam, Netherlands; ³Clinical Chemistry, Erasmus Medical Centre, Rotterdam, Netherlands; ⁴Pathology, Erasmus Medical Centre, Rotterdam, Netherlands; ⁵Pathology, Academic Medical Centre, Amsterdam, Amsterdam, Netherlands.
Patients expressing the cytochrome P450 (CYP) 3A5 gene require a higher tacrolimus dose to achieve therapeutic exposure compared with non-expressers. This randomized-controlled study investigated if…
2016 American Transplant Congress
Elderly Kidney Transplant Recipients Need Optimized Immunosuppression According to Comorbidity and Infection.
E. Kang,¹ S. Park,¹ S. Park,¹ S. Yang,² I. Jung,³ S.-K. Park,⁴ Y. Kim,⁵ D.-J. Han,¹ Y. Kim,¹ J. Lee.⁶
¹Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea; ²Kidney Research Institute, Seoul National University College of Medicine, Seoul, Korea; ³Department of Surgery, Seoul National University Boramae Medical Center, Seoul, Korea; ⁴Department of Internal Medicine, Asan Medical Center and University of Ulsan College of Medicine, Seoul, Korea; ⁵Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea; ⁶Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Korea.
Backgrounds: The numbers of elderly kidney transplantation is increasing, but there are limited studies about the use of immunosuppressant in this group. We investigated the…
2016 American Transplant Congress
The Role of Short-Term Ventricular Assist Device in Patients with Cardiogenic Shock – Is It Really a Solution?
A. Popov, M. Zeriouh, S. Anton, W. Alexander, Z. Bartlomiej, D. Garcia, P. Mohite, A. Padukone, A. Koch, O. Ananiadou, L. Fazekas, A. Simon.
Department of Cardiothoracic Transplantation and Mechanical Circulatory Support, Royal Brompton & Harefield NHS Foundation Trust, London, United Kingdom.
Background: Low cardiac output syndrome is associated with significant mortality. In patients with refractory low cardiac output left ventricular assist devices (VAD) are used to…