Am J Transplant, Volume 16, Suppl 3 Archives - Page 102 of 180 - ATC Abstracts

2016 American Transplant Congress
Cold Storage Stabilization of Gap Junctions Reduces Post Transplant Ischemia Reperfusion Injury.
R. Finnegan,¹ P. Zhu,¹ S. Stephenson,¹ K. Patel,² S. Nadig,^1,2,3 C. Atkinson.^1,2,3
¹Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC; ²Department of Surgery, Medical University of South Carolina, Charleston, SC; ³South Carolina Investigators in Transplantation, Medical University of South Carolina, Charleston, SC.
Purpose: Organ procurement, cold storage and ischemia reperfusion injury (IRI) promote inflammation, which induces endothelial cell (EC) activation and dysfunction post transplantation. EC gap junctions…
2016 American Transplant Congress
Regulatory T Cell Infusion Can Enhance Memory T Cell and Alloantibody Responses in Lymphodepleted Nonhuman Primate Heart Allograft Recipients.
M. Ezzelarab,¹ H. Zhang,¹ L. Lu,¹ H. Guo,¹ A. Zahorchak,¹ R. Wiseman,² M. Nalesnik,³ J. Bhama,¹ D. Cooper,¹ A. Thomson.^1,4
¹Surgery, University of Pittsburgh, Starzl Institute, Pittsburgh, PA; ²Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI; ³Pathology, University of Pittsburgh, Pittsburgh, PA; ⁴Immunology, University of Pittsburgh, Pittsburgh, PA.
Background:The ability of regulatory T cells (Treg) to prolong allograft survival and promote transplant tolerance in lymphodepleted rodents is well-established. Few studies have addressed the…
2016 American Transplant Congress
Positive Lymphocytes Flow Cytometry Crossmatch Due to AT1r Antibodies in Absence of HLA-DSA.
M. Ramirez,¹ D. Kershaw,² Y. Huang,² J. Magee,³ M. Samaniego,² T. Williams,¹ D. Schauss,¹ T. Franks,¹ Y. Kleyman,¹ D. Ramon.¹
¹Department of Pathology, University of Michigan School of Medicine, Ann Arbor, MI; ²Department of Internal Medicine, UMICH, Ann Arbor; ³Department of Surgery, UMICH, Ann Arbor.
The angiotensin II type 1 receptor (AT1r) plays a key role in the renin-angiotensin system. Anti-AT1R antibodies (Abs) have been associated with both acute and…
2016 American Transplant Congress
Natural History of Response to Wounding in Human Kidney Transplants.
K. Famulski,¹ J. Venner,^2,1 J. Reeve,¹ P. Halloran.¹
¹University of Alberta, Edmonton, AB, Canada; ²University of Queensland, Brisbane, Queensland, Australia.
In both primary kidney diseases and kidney transplants, the extent of fibrosis is a key indicator of stage, progression, and prognosis. Much debate focuses, however,…
2016 American Transplant Congress
Impact of Cold Ischemia Time on the Outcomes of Kidneys with KDPI >85%: Mate Kidney Analysis.
M. Sampaio, B. Chopra, K. Sureshkumar.
Nephrology, Allegheny General Hospital, Pittsburgh, PA.
The new kidney allocation scheme recommends simultaneous local and regional offer for kidneys with KDPI >85% in order to minimize discard rates. It is unclear…
2016 American Transplant Congress
Hepatitis E Virus (HEV) Infection Among Kidney Transplant Patients in a Northeast US Center.
M. Lim,¹ S. Kamili,² T. Greene,² A. Tejada-Strop,² J. Drobeniuc,² M. Vanderveen,¹ R. Bloom.¹
¹Division of Nephrology, Perelman School of Medicine, Philadelphia, PA; ²Division of Viral Hepatitis, Centers for Disease Control, Atlanta, GA.
Aim. To determine the prevalence of HEV infection in kidney candidates and assess chronic HEV infection among transplant recipients. Methods. We recruited 244 kidney transplant…
2016 American Transplant Congress
Recurrence of FSGS Post Kidney Transplantation: Salvage Therapy with ACTHAR® Gel.
P. Vaitla, D. Daswatta, A. Guasch.
Transplant, Emory University, Atlanta, GA.
Recurrence of FSGS post kidney transplantation: Salvage therapy with ACTHAR® gel.Introduction:Recurrence of FSGS post kidney transplantation may reach 25-50%. Failure of treatment or incomplete remission…
2016 American Transplant Congress
The Impact of Early Acute Rejection and Delayed Graft Function on Graft Outcomes at Six Months in Adult Deceased Donor Kidney Recipients.
D. Keith, G. Vranic, A. Nishio Lucar.
University of Virginia, Charlottesville, VA.
Graft function as determined by GFR is an important predictor of long-term graft and patient survival after deceased donor kidney transplantation. KDPI is an important…
2016 American Transplant Congress
De Novo Anti-HLA DSA Characteristics and Subclinical Antibody Mediated Kidney Allograft Injuries.
T. Yamamoto, Y. Watarai, A. Takeda, M. Okada, M. Tsujita, T. Hiramitsu, N. Goto, S. Narumi, K. Morozumi, K. Uchida, T. Kobayashi.
Nagoya daini red cross hospital, Nagoya, Japan.
Background It has been reported that de novo donor-specific HLA antibody (dn DSA) production is associated with chronic antibody-mediated rejection (CAMR) which leads to poor…
2016 American Transplant Congress
Motivation and Stress Associated with Non-Directed Kidney Donation.
J. Wiseman,¹ D. Berglund,¹ C. Jacobs,¹ D. Larson,¹ C. Garvey,¹ M. Vogues, S. Rein,¹ O. Sanchez,¹ C. Radecki Breitkopf,² H. Ibrahim,¹ A. Matas.¹
¹U of MN, Mpls; ²Mayo Clinic, Rochester.
Background: Nondirected kidney donors (NDDs) are unique in that they have the risks of nephrectomy but often do not have the benefit of seeing the…