2016 American Transplant Congress
Is SVR Associated with Improved Hepatic Function in Hepatitis C Gen 1 Pts with Cirrhosis 1 Year After Completing Treatment with Sofosbuvir + Simeprevir +/- Ribavirin?
Background: Combination antiviral therapy involving Sofosbuvir (SOF) & Simeprevir (SIM) +/- Ribavirin (RBV) is a relatively safe & effective Tx option in pts with gen…2016 American Transplant Congress
The Distance Between Us: The Landscape of Recipient-Specific Loss-of-Function in Solid Organ Transplantation and Association with Rejection-Free Graft Survival.
Purpose: This study aims to comprehensively identify genes that are inactivated in both copies in transplant recipients but not in their respective donors, uncovering a…2016 American Transplant Congress
Inclusion of Human Tissue Factor Pathway Inhibitor or Thrombomodulin Transgenes Attenuates Critical Consumptive Thrombocytopenia in Cardiac Xenotransplantation.
ObjectiveA major obstacle in the success of cardiac xenotransplantation has been the development of significant consumptive thrombocytopenia, frequently limiting recipient survival. Advances in genetic engineering…2016 American Transplant Congress
Conditional Long Term Intestine Patient and Graft Survival Is Improving Under rATG Immunosuppression in Pediatric Intestine Transplantation.
Aim: We reviewed conditional graft survival and short and long term improvements in children receiving rATG (rabbit anti-thymocyte globulin) immunosuppression for intestine transplantation at a…2016 American Transplant Congress
Hematopoietic Cell Transplant and Solid Organ Transplantation: A First Report of the U.S. Experience.
Surgery, Division of Transplant Surgery, University of Pennsylvania, Philadelphia, PA.
The prevalence of patients who receive both a hematopoetic cell(HCT) and solid organ transplantation(SOT) is rising. There have been no large scale studies of HCT…2016 American Transplant Congress
Live Donor Champion Program: Time to Redefine Living Liver Donation.
UVA Surgery, Charlottesville, VA.
Live Donor Champion (LDC) Programs promote the advocacy for living donor transplantation by patients' family members or friends. Hereby, we conducted a prospective 9 month…2016 American Transplant Congress
Potential Applications of Viral miRNA Assays in the Management of Transplant Patients with Polyomavirus BK Infection.
Background: BKV encodes two miRNAs from a single precursor: BKV-miR-B1-5p & BKV-JCV-miR-BJ1-3p. These viral miRNAs direct cleavage of large T antigen mRNAs, downregulate viral T…2016 American Transplant Congress
Evaluation of the Major Adverse Cardiac Events Risk with Everolimus-Based Calcineurin Inhibitor Reduction or Withdrawal Regimen in Liver Transplant Recipients: 3-Year Post-Hoc Analysis of the Randomized H2304 Extension Study.
1Novartis Pharma AG, Basel, Switzerland; 2Novartis Pharmaceuticals Corporation, East Hannover.
Purpose:Cardiovascular disease (CVD) is one of the leading causes of death in liver transplant recipients (LTxRs). Impaired glomerular filtration rate (GFR) is a risk factor…2016 American Transplant Congress
High-Risk Pharmacogenetic (PGx) Variants in Kidney Transplant (tx) Recipients.
1UofMN, Mpls; 2MMRF, Mpls; 3HCMC, Mpls; 4UAB, Birmingham.
Kidney tx recipients carry a high burden of comorbidities, and some of the medications for these conditions have genetic predictors of efficacy and toxicity. These…2016 American Transplant Congress
Impact of Morbid Obesity on Breakthrough CMV Infection in Kidney Transplant Recipients.
Medical University of South Carolina, Charleston, SC.
Purpose: The aim of this study was to assess the impact of obesity on risk for cytomegalovirus (CMV) infection after kidney transplantation as well as…
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