ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Obesity Is Associated with Increased Risk of ESRD Among Living Kidney Donors.

    J. Locke,1 C. Lewis,1 R. Reed,1 V. Kumar,1 D. Sawinski,2 A. Massie,3 P. MacLennan,1 R. Mannon,1 R. Gaston,1 D. Segev.3

    1School of Medicine, University of Alabama at Birmingham, Birmingham, AL; 2School of Medicine, University of Pennsylvania, Philadelphia, PA; 3School of Medicine, Johns Hopkins University, Baltimore, MD.

    Background: Living kidney donor (LKD) demographics have changed, and transplant centers have relaxed selection criteria to include LKDs who are obese. Prior studies of LKDs…
  • 2016 American Transplant Congress

    Kidney Donor Profile Index Trend Analyses.

    D. Vikraman, K. Ravindra, S. Sanoff, W. Irish, U. Patel, D. Sudan.

    Surgery, Duke University Medical Center, Durham, NC.

    IntroductionIn spite of improved outcomes associated with the usage of extended criteria donor (ECD) kidneys, the number of kidney transplants (KT) using this donor population…
  • 2016 American Transplant Congress

    Anti-IL6R Therapy (Tocilizumab) Improves Long-Term Patient & Graft Survival in Patients with Chronic Antibody-Mediated Rejection and Transplant Glomerulopathy.

    J. Choi, A. Vo, M. Haas, D. Puliyanda, S. Louie, A. Peng, J. Kahwaji, R. Villicana, I. Kim, J. Mirocha, S. Jordan.

    Comprehensive Transplantation Center, Cedars-Sinai Medical Center, Los Angeles, CA.

    Introduction:Extending the functionality of renal allografts is an essential goal of transplant medicine. HS patients (pts) are at increased risk for chronic ABMR (CABMR) due…
  • 2016 American Transplant Congress

    Impact of Pretransplant Non-Donor-Specific HLA Immunization: Mainly Class 1 Immunization Leads to Poor Immunologic Outcome and Graft Loss.

    O. Staeck, F. Halleck, A. Staeck, L. Lehner, M. Duerr, E. Schrezenmeier, K. Budde, D. Khadzhynov.

    Nephrology, Charite, Berlin, Germany.

    Background Anti-HLA immunization measured as Panel Reactive Antibodies (PRA) is known to have a negative impact on patient and graft survival. The influence of pre-transplant…
  • 2016 American Transplant Congress

    The Optimal Time Point for Steroid Withdrawal After Kidney Transplantation Is One Year After Engraftment.

    M. Haller,1 M. Kammer,1,2 A. Kainz,2 G. Heinze,1 R. Oberbauer.1,2

    1Center for Medical Statistics, Informatics and Intelligent Systems (CeMSIIS), Medical University of Vienna, Vienna, Austria; 2Department of Medicine, Medical University of Vienna, Vienna, Austria.

    The optimal time of steroid withdrawal after kidney transplantation remains elusive, since RCTs can evaluate one predefined time point. Thus we analyzed all first kidney…
  • 2016 American Transplant Congress

    Impact of Delayed Graft Function Varies by Demographic and Clinical Characteristics in Deceased Donor Kidney Transplantation.

    C. Liao, A. Massie, S. Bae, A. Muzaale, D. Segev.

    JHU, Baltimore.

    Single-center studies have suggested potential differences in the impact of DGF by recipients' biological susceptibility, quality of allograft, and immune compatibility. The goal of this…
  • 2016 American Transplant Congress

    Association of Neighborhood Poverty and Living Donor Kidney Transplant Rates by Donor Relationship to Recipient.

    G. Vranic, A. Nishio Lucar, D. Keith.

    Medicine, University of Virginia, Charlottesville, VA.

    Background: Living donor (LD) kidney transplant is associated with increased access to transplant and improved patient and allograft outcomes. Despite the known benefits, LD rates…
  • 2016 American Transplant Congress

    Is C3d-fixing Donor Specific HLA Antibody Detection Really Necessary?

    P. Malvezzi,1 M. Villemaire,1 A. Bourdin,2 T. Jouve,1 R. Tetaz,1 B. Janbon,1 N. Terrier,3 D. Masson.2

    1Service de Néphrologie, Grenoble University Hospital, Grenoble, France; 2Laboratoire d'Histocompatibilité, EFS, Grenoble, France; 3Service d'Urologie, Grenoble University Hospital, Grenoble, France.

    Introduction: Chronic antibody–mediated rejection is the main cause of late kidney graft loss. The identification of donor-specific antibodies (DSA) in the serum is one of…
  • 2016 American Transplant Congress

    Malignancies Contribute to Presensitization with Alloreactive T-Cells in Kidney Transplant Recipients.

    T. Schachtner,1,2 M. Stein,2 P. Reinke.1,2

    1Nephrology and Internal Intensive Care, Charite Campus Virchow Clinic, Berlin, Germany; 2Berlin-Brandenburg Center for Regenerative Therapies, Charite Campus Virchow Clinic, Berlin, Germany.

    Alloreactive T-cells have been suggested to impact allograft outcome due to a higher incidence of acute rejection in the initial period after kidney transplantation. Knowledge…
  • 2016 American Transplant Congress

    Human B Cell Cytokines Predict Renal Allograft Rejection and Early Transplant Outcomes.

    A. Cherukuri, R. Mehta, S. Ogunde, S. Hariharan, D. Rothstein.

    UPMC, Pittsburgh.

    In renal transplantation, non-invasive biomarkers that are predictive and allow for early intervention are limited. Here we report findings from a prospective longitudinal study of…
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