Am J Transplant, Volume 16, Suppl 3 Archives - ATC Abstracts

2016 American Transplant Congress
Outcomes in Lung Transplant Patients Requiring Extracorporeal Membrane Oxygenation (ECMO) in the Perioperative Period.
A. Habertheuer, M. Williams, S. Miller, E. Cantu, C. Bermudez, P. Vallabhajosyula.
Cardiovascular Surger, Hospital of the University of Pennsylvania, Philadelphia, PA.
Objective As ECMO therapy is increasingly used to bridge high-risk patients with end-stage respiratory failure to lung transplantation, outcomes of this strategy employed in the…
2016 American Transplant Congress
C3 Glomerulopathy Secondary to Complement Factor H Inhibition by Monoclonal Kappa Light Chains.
C. Blosser,¹ Y. Zhang,² T. Dhawale,³ C. Johnson,¹ P. Hendrie,³ R. Smith.²
¹Medicine, University of Washington, Seattle, WA; ²Medicine & Surgery, University of Iowa, Iowa City, IA; ³Medicine, Seattle Cancer Care Alliance, Seattle, WA.
Background: Monoclonal gammopathy of renal significance (MGRS) implies a causal relationship between clonal B cell proliferation and renal disease and is associated with high morbidity…
2016 American Transplant Congress
Anti-HLA Antibodies in Allogeneic and Autologous Hematopoietic Stem Cell Transplantation.
A. Bertocchi, L. Requiao-Moura, M. Torres, E. Tonato, M. Durao Junior, A. de Matos, N. Hamershclak, A. Pacheco-Silva.
Kidney Transplantation, Hematology, Histocompatibility Laboratory, Hospital Israelita Albert Einstein, Sao Paulo, Brazil.
Introduction: Anti-HLA antibodies have been associated with graft rejection in solid organ and hematopoietic stem cell transplantation (HSCT). The aim of this study was describe…
2016 American Transplant Congress
Association of Genetic Polymorphisms in Complement Independent Pathways with Donor Specific Antibodies in Kidney Allograft Recipients.
Y. Chang,^1,2 T. Shah,^1,3 D. Min.¹
¹Western University of Health Sciences, Pomona, CA; ²Mendez National Institute of Transplantation Foundation, Los Angeles, CA; ³St. Vincent Medical Center, Los Angeles, CA.
Background: It is known that detection of donor specific antibodies (DSA) is associated with antibody mediated rejection (AMR) and poor allograft outcomes. DSA mediates graft…
2016 American Transplant Congress
Safety, Efficacy, and Cost Saving Potential of Various Weight-Based Dosing for Thymoglobulin Induction Therapy in Kidney Transplant Recipients.
R. Miller,¹ H. Meadows,¹ S. Strout,¹ T. Veasey,¹ A. Mardis,¹ J. Fleming,¹ C. Mardis,¹ N. Pilch,¹ K. Chavin,² D. Taber.²
¹Department of Pharmacy, Medical University of South Carolina, Charleston, SC; ²Department of Surgery, Medical University of South Carolina, Charleston, SC.
Introduction: There are limited data assessing the appropriate weight to use when dosing Thymoglobulin for induction therapy. The aim of this study is to assess…
2016 American Transplant Congress
Virtual Crossmatching Under the New KAS: Safely Bypassing a Physical Crossmatch When Allocating Kidneys to Highly Sensitized Candidates.
R. Bray,¹ R. Parsons,² N. Turgeon,² H. Gebel.¹
¹Pathology, Emory University, Atlanta, GA; ²Emory Transplant Center, Emory University, Atlanta, GA.
AIM: On 12/4/2014, the OPTN implemented a new KAS for deceased donor(DD) transplants which, among many changes, increased priority for highly sensitized (HS) candidates (cPRA>98%).…
2016 American Transplant Congress
New Kidney Allocation System: Friend or Foe?
F. Cabeza,² A. Dejman,¹ A. Torres,³ J. Gaynor,² P. Ruiz,² D. Roth,² W. Kupin,² G. Burke,² G. Ciancio,² L. Chen,² R. Vianna,² A. Mattiazzi,² G. Guerra.²
¹Nephrology and Hypertension, University of Miami, Miami, FL; ²Kidney Transplant, Miami Transplant Institute, Miami, FL; ³Internal Medicine, Hospital San Jose Tec de Monterrey, Mexico D.F., Mexico.
BACKGROUND The new kidney allocation (KAS) system was implemented 12/2014 to increase recipient life years gained annually and facilitate the transplantation of harder to match…
2016 American Transplant Congress
Reciprocal Effects of HDAC1 and HDAC2 Deletion on Renal Cold Ischemia Survival and Nuclear Co-Repressor Complex Expression.
D. Aufhauser Jr,¹ D. Murken,¹ Z. Wang,¹ A. Samanta,² G. Ge,¹ T. Bhatti,³ W. Hancock,^2,3 M. Levine.¹
¹Surgery, University of Pennsylvania, Philadelphia, PA; ²Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA; ³Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA.
Introduction: Class I histone/protein deacetylases (HDACs) 1 and 2 bear >85% protein sequence homology and conventionally are thought to have similar function via occupancy in…
2016 American Transplant Congress
Hydrogen Sulfide Treatment Mitigates Donor Tissue Necrosis During Prolonged Cold Storage and Improves Survival Following Allogeneic Renal Transplantation.
I. Lobb,^1,3 W. Liu,² J. Jiang,³ D. Lian,³ A. Sener.^1,3,4
¹Microbiology and Immunology, Western University Canada, London, ON, Canada; ²Pathology, Western University Canada, London, ON, Canada; ³Matthew Mailing Centre for Translational Transplant Studies, London Health Sciences Centre, London, ON, Canada; ⁴Surgery, Western University Canada, London, ON, Canada.
Organ procurement is inherently associated with ischemia-reperfusion injury (IRI), resulting from loss and subsequent restoration of blood flow, which is detrimental to short- and long-term…
2016 American Transplant Congress
Health Insurance Trends in United States Living Kidney Donors.
J. Rodrigue,^1,2 A. Fleishman.¹
¹Surgery, Beth Israel Deaconess Medical Center, Boston, MA; ²Surgery, Harvard Medical School, Boston, MA.
The aim of this study was to examine health insurance trends in living kidney donors (LKDs) in the United States and their association with donor…

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