ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Mapping Heterogeneity in Antibody-Mediated Rejection Using Molecular Phenotypes and Archetype Analysis.

    J. Reeve,1 P. Halloran.1,2

    1Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada; 2Medicine, University of Alberta, Edmonton, AB, Canada.

    Archetype analysis is a method for identifying new relationships among samples without subdividing them into classes, finding a limited number of archetypical cases and calculating…
  • 2016 American Transplant Congress

    Predictors of eGFR Slope at One Year in Kidney Transplants – A Big Data Approach.

    J. Zhang, Z. Su, D. Taber, J. Marsden, W. Moran, P. Mauldin, T. Srinivas.

    MUSC, Charleston.

    Background: Estimated glomerular filtration rate (eGFR), a predictor of graft loss (GL) in kidney transplantation could inform intervention. National data yield eGFRs at fixed time…
  • 2016 American Transplant Congress

    Wait List Removals and Transplant Rates Are Significantly Associated with Transplant Center Performance Oversight.

    J. Schold, L. Buccini, E. Poggio, S. Flechner, D. Goldfarb.

    Cleveland Clinic, Cleveland, OH.

    Prior studies indicate that low performance(LP) center evaluations by the SRTR are associated with reductions in transplant volume. There is limited information to determine whether…
  • 2016 American Transplant Congress

    Utilization and Discard of HCV+ Donor Livers in the Advent of Direct-Acting Antiviral Therapy.

    M. Bowring, L. Kucirka, A. Massie, X. Luo, M. Sulkowski, D. Segev, C. Durand.

    JHU, Baltimore.

    While 45% of liver candidates are hepatitis C (HCV)-antibody positive (+) and might benefit from a HCV+ donor liver, only a small proportion receive one.…
  • 2016 American Transplant Congress

    Insights into the Treatment of Post-Transplant Focal Glomerulosclerosis: Experience Gained from a Concise Diagnostic and Management Protocol.

    K. Koutroutsos,1 R. Charif,1 L. Moran,2 J. Moss,2 T. Cook,2 C. Roufosse,2 D. Taube,1 M. Loucaidou.1

    1Kidney and Transplant Centre, Imperial Healthcare NHS Trust, London, United Kingdom; 2Department of Histopathology, Imperial Healthcare NHS Trust, London, United Kingdom.

    Background: Recurrence of Focal Glomerulosclerosis (FSGS) after kidney transplantation is associated with poor graft survival. We present results from a concise diagnostic and management protocol…
  • 2016 American Transplant Congress

    Donor-Recipient Absolute Weight Mismatch and the Risk of Graft Loss in Renal Transplantation.

    A. Miller,1 B. Kiberd,1 I. Alwayn,2 K. Tennankore.1

    1Medicine, Division of Nephrology, Dalhousie University, Halifax, NS, Canada; 2Surgery, Multi Organ Transplant Program, Dalhousie University, Halifax, NS, Canada.

    Background: Relatively smaller kidney donor to recipient size is proposed to result in increased graft loss due to nephron underdosing and hyperfiltration injury but few…
  • 2016 American Transplant Congress

    Composite Score to Define the Risk of Allograft Loss After Standard-of-Care Treatment of Antibody-Mediated Rejection in Kidney Transplantation.

    D. Viglietti,1 A. Loupy,2 J. Duong Van Huyen,2 J. Verine,1 A. Zeevi,3 C. Legendre,2 D. Glotz,1 C. Lefaucheur.1

    1Saint-Louis Hospital, Paris, France; 2Necker Hospital, Paris, France; 3University of Pittsburgh Medical Center, Pittsburgh.

    The development of a reliable surrogate endpoint for allograft survival after AMR treatment is a current unmet need in clinical transplantation (FDA AMR Workshop). We…
  • 2016 American Transplant Congress

    Pre-Donation Weight Loss Postpones Living Kidney Donation without Attaining the Desired Weight Maintenance in the Midterm.

    P. Ventura-Aguiar, E. De Sousa-Amorim, J. Campistol, F. Diekmann, F. Oppenheimer, I. Revuelta.

    Renal Transplant Unit, Hospital Clinic, Barcelona, Spain.

    Pre-donation weight loss in living kidney donation has two main objectives: reduce surgical risk, and decrease long-term complications from obesity and glomerular hypertrophy secondary to…
  • 2016 American Transplant Congress

    MicroRNAs in Urinary Sediments as Non-Invasive Tool to Detect Acute Rejection After Kidney Transplantation.

    E. Gielis,1,2 J. Anholts,2 H. de Fijter,3 I. Bajema,4 F. Claas,2 M. Eikmans.2

    1Laboratory of Experimental Medicine and Pediatrics, University of Antwerp, Antwerp, Belgium; 2Immunohematology, LUMC, Leiden, Netherlands; 3Nephrology, LUMC, Leiden, Netherlands; 4Pathology, LUMC, Leiden, Netherlands.

    MicroRNAs in urine are suitable targets for non-invasive detection of acute rejection (AR), since they represent relatively stable analytes. Indeed, we found that PCR signals…
  • 2016 American Transplant Congress

    Influence of AKIN Stage on the Outcome of Deceased Donor Kidney Transplantation (DDKTx).

    I. Qaqish, D. Haakinson, K. Reddy, M. Smith, H. Khamash, H. Raymond.

    Mayo Clinic, Phoenix, AZ.

    BackgroundTransplanting kidneys from donors with AKI is one of the methods to minimize the disparity between numbers of listed patient and donor pool. Our aim…
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