Date: Saturday, May 30, 2020
Session Time: 3:15pm-4:45pm
Presentation Time: 3:15pm-3:27pm
*Purpose: In October 2018, the US heart allocation system expanded the number of priority “Status” tiers from 3 to 6 and added cardiogenic shock requirements. This study will aim to determine the impact of the new policy on the treatment practices of transplant centers.
*Methods: Initial listing data on all adult heart candidates listed from December 1st, 2017 to April 30th, 2019 were collected from the Scientific Registry of Transplant Recipients. The Status-qualifying treatments (or exception requests) and hemodynamics at listing of a post-policy cohort (December 2018 to April 2019) were compared to a seasonally-matched pre-policy cohort (December 2017 to April 2018). Candidates in the pre-policy cohort were reclassified into 6-tier statuses using treatment, diagnosis, and hemodynamics.
*Results: Comparing the post-policy cohort (N =1,567) to the pre-policy cohort (N = 1,606), there were significant increases in listings justified with extra-corporeal membrane oxygenation (ECMO) (+1.2%), intra-aortic balloon pumps (IABP) (+ 4 %) and exceptions (+ 12%). Listings with low-dose inotropes (-18%) and high-dose inotropes (-3%) significantly decreased. The observed 6-Status distribution had more Status 2 (+14%) candidates than expected and less Status 3 (- 5%), Status 4 (- 4%) and Status 6 (-8%) candidates than expected (p-values < 0.01 for all comparisons).
*Conclusions: After implementation of the new heart allocation policy, transplant centers listed more candidates with ECMO, IABP and exception requests and less candidates with inotrope therapy than expected, leading to significantly more high-priority Status listings than anticipated. If these early trends persist, the new allocation system may not function as intended.
To cite this abstract in AMA style:Chung K, Anderson AS, Siegler M, Churpek MM, Parker W. The Impact of the New Heart Allocation Policy on the Treatment of United States Adult Heart Transplant Candidates [abstract]. Am J Transplant. 2020; 20 (suppl 3). https://atcmeetingabstracts.com/abstract/the-impact-of-the-new-heart-allocation-policy-on-the-treatment-of-united-states-adult-heart-transplant-candidates/. Accessed October 24, 2020.
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