Session Name: Kidney: Cardiovascular and Metabolic Complications
Session Date & Time: None. Available on demand.
*Purpose: With increasing life expectancy, there has been increase in transplant rates amongst elderly recipients who often have more comorbidities than younger recipient. The aim of the study was to evaluate the outcomes of septuagenarian kidney transplant (KT) recipients.
*Methods: Single-center, retrospective cohort study was conducted to evaluate outcomes of recipients more than 70 years old who underwent KT with respect to 1-3-5 year graft and patient survival and peri-operative outcomes like length of stay and delay graft function. For assessment of the results which can be meaningful, we compared it to recipients between age 65 and 69 who underwent KT. We divided the groups in cohort 1 65-69 years old, and cohort 2 70-79 years old. EHR charts were reviewed for hospital stay, need for ICU management, delay graft function and primary non function. We adjusted for patient comorbidities common in this patient population, which include, hypertension, diabetes mellitus, coronary artery disease, cerebral vascular disease, peripheral vascular disease, and chronic obstructive pulmonary disease. T-test was used for comparisons of parametric continuous variables and Mann-Whitney U test was utilized for nonparametric continuous variables.
*Results: From April 2014 to July 2019 55 kidney transplants were performed in cohort 1and 28 in cohort 2. Cohort 1 54% were male, 42% White, 47% Black, 11% other; 27% received living donor (LD), 23% donation after cardiac death (DCD) and 49% brain death donor (BDD). In cohort 2 40% were male, 53% were white, 43% were black and 4% other. 32% received LD, 10% DCD, 58% BDD. One-, three- and five-year graft and patient survival were 94%, 91% and 91%in cohort 1 and 100% in cohort 2 (p=NS). Mean length of stay (LOS) was 8 days for both cohorts with a median of 6 days. Readmission in first 30 days was 18.2% and 33.3% respectively, delay graft function (DGF) was 18.2% and 22.2% respectively.
*Conclusions: We did not find significant differences between the 65-69 year old and the 70-79 year old after adjusting for comorbidities. We found that more women and white patients were in the cohort 2. Kidney transplant is a safe and adequate procedure in septuagenarian recipients.
To cite this abstract in AMA style:Rodriguez PSerrano, Vonderau J, Szempruch K, Desai CS. Renal Transplant is Safe in Septuagenarians [abstract]. Am J Transplant. 2021; 21 (suppl 3). https://atcmeetingabstracts.com/abstract/renal-transplant-is-safe-in-septuagenarians/. Accessed June 11, 2021.
« Back to 2021 American Transplant Congress