Date: Tuesday, May 5, 2015
Session Time: 5:30pm-6:30pm
Presentation Time: 5:30pm-6:30pm
Location: Exhibit Hall E
The program-specific reports produced by SRTR include 1-month, 1-year, and 3-year posttransplant graft and patient survival measures. The 1-month and 1-year measures use the same 2.5-year cohort of transplant recipients. The 3-year measures use an older non-overlapping 2.5-year cohort. The 3-year measures have limitations: they are calculated for older cohorts, so their relevance for current program evaluation is suspect. Follow-up beyond 3 years is ignored. Graft failure and patient death events that occurred during the first year posttransplant are included in the 3-year measures, so 3-year measures are not distinct from 1-year measures. Separate 5-year conditional survival models were built for deceased and living donor adult kidney graft and patient survival using the 3-year model cohorts, excluding recipients with first-year events to avoid the limitations of the 3-year models. For each model, a hazard ratio (HR) was calculated for each program as a performance measure. HRs tended to be least well correlated between the 1-year and 5-year models (Table 1). There was weak correlation between 1-year and 5-year estimated program HRs for deceased donor adult graft survival (Fig. 1), and substantial program-level variability in 5-year conditional graft survival. Although how much long-term outcomes are determined by factors controlled by transplant programs is unclear, these results suggest that 5-year conditional survival metrics could be a useful supplement to 1-year survival metrics.
|Deceased Donor||Living Donor|
|Adult Kidney Models||Graft||Patient||Graft||Patient|
To cite this abstract in AMA style:Salkowski N, Hunsicker L, Snyder J, Kasiske B. Program-Effect Attenuation With Time Posttransplant [abstract]. Am J Transplant. 2015; 15 (suppl 3). https://atcmeetingabstracts.com/abstract/program-effect-attenuation-with-time-posttransplant/. Accessed January 24, 2020.
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