Abstracts Archive - Page 776 of 1683 - ATC Abstracts

2018 American Transplant Congress
ABO‐incompatible Deceased Donor Liver Transplantation
X. Luo, C. Haugen, A. Thomas, J. Garonzik-Wang, D. Segev.
Johns Hopkins, Baltimore, MD.
ABO-incompatible liver transplantation (ILT) has increased over the past decade despite reports suggesting that adult ILT recipient have worse outcomes than ABO-compatible liver transplant (CLT)…
2018 American Transplant Congress
Portal Vein Flow as an Indicator of Liver Transplantation for Acute Liver Failure
C-.H. Cheng,¹ C. Lee,² Y-.C. Wang,¹ T-.H. Wu,¹ C-.F. Lee,¹ T-.J. Wu,¹ H. Chou,¹ K-.M. Chan,¹ W-.C. Lee.¹
¹Division of Liver and Transplantation Surgery, Department of General Surgery, Chang-Gung Memorial Hospital, Chang-Gung University College of Medicine, Taoyuan, Taiwan; ²Department of Hepatology, Chang-Gung Memorial Hospital, Chang-Gung University College of Medicine, Taoyuan, Taiwan.
Background: Liver transplantation is the most effective treatment for acute liver failure. Timing of liver transplantation is important to rescue the dying patients. This study…
2018 American Transplant Congress
Outcomes of Liver Transplant in Sequential Eras in Patients with Polycystic Liver Disease at Various Stages of Disease
C. Desai,¹ J. Shurney,¹ P. Serrano Rodriguez,¹ A. Barritt,¹ D. Gerber,¹ A. Gruessner.²
¹University of North Carolina, Chapel Hill, NC; ²SUNY Downstate Medical Center, Brooklyn, NY.
Patients with polycystic liver disease (PLD) receive liver transplants at various time points in their disease process. Some patients receive liver transplant alone (L), some…
2018 American Transplant Congress
Hyaluronic Acid as Early Biomarker of Graft Loss after Liver Transplantation: A Prospective Study
A. Rostved,¹ S. Ostrowski,² L. Peters,³ J. Lundgren,³ C. Sørensen,¹ H-.C. Pommergaard,¹ J. Hillingsø,¹ A. Rasmussen.¹
¹Department of Surgical Gastroenterology and Transplantation, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark; ²Department of Clinical Immunology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark; ³CHIP, Department of Infectious Diseases, Section 2100, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
Introduction: Improved diagnosis and understanding the pathophysiology of early allograft dysfunction is essential to improve the short-term outcome after liver transplantation (LT). Hyaluronic acid (HA)…
2018 American Transplant Congress
Involvement of Aldehyde Dehydrogenase 2 (ALDH2) in Fatty Liver Graft Protection Mechanisms against Cold Ischemic Injury
A. Panisello-Rosello,¹ A. Lopez,² C. Castro,² S. Bellogi,¹ E. Folch-Puy,¹ A. Rolo,³ C. Palmeira,³ R. Adam, J. Roselló-Catafau.
¹Experimental Pathology, Instituto de Investigaciones Biomédicas de Barcelona, Barcelona, Catalonia, Spain; ²INSERM U935, Hôpital Paul Brousse, Paris, France; ³Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal.
Aldehyde dehydogenase (ALDH2) is a mitochondrial enzyme that recently has been involved in the cardioprotection against ischemia injury. No data are reported on the potential…
2018 American Transplant Congress
Circulating Wnt Pathway Factors Are Non-Invasive Biomarkers of Transplant Vascular Injury
M. Seifert,¹ A. Malone,² L. Boohaker,¹ J. Gaut,² S. Jain,² D. Brennan,^2,3 R. Mannon.¹
¹UAB School of Medicine, Birmingham; ²Washington University, St. Louis; ³Johns Hopkins University, Baltimore.
Purpose: Transplant vascular injury (TVI) is a major cause of renal allograft failure and is resistant to treatment. Non-invasive pathogenic biomarkers of TVI would provide…
2018 American Transplant Congress
Time and Perfusate Dependent Molecular Response in Ex Vivo Lung Perfusion
P. Dromparis,¹ N. Aboelnazar,² S. Wagner,¹ S. Himmat,² C. White,² J. Luc,² D. Freed,² J. Nagendran,² M. Mengel,¹ B. Adam.¹
¹Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Canada; ²Department of Surgery (Cardiac), University of Alberta, Edmonton, Canada.
Lung transplantation has limited organ utilization and high rates of primary graft dysfunction, in part due to acute lung injury (ALI). Cold static preservation (CSP)…
2018 American Transplant Congress
Characterization of Exosomal DNA from Human Lung Transplant Recipients
S. Bansal, M. Sharma, R. Walia, R. Bremner, M. Smith, T. Mohanakumar.
Norton Thoracic Institute, St. Joseph's Hosp & Med Ctr, Phoenix.
Exosomes are small vesicles which contains biological molecules including proteins, RNA`s and miRNAs. It has been reported that exosomes may contain ds DNA originated from…
2018 American Transplant Congress
Identification of Exosomal Proteins from Human Lung Transplant Recipients
S. Bansal,¹ P. Pirrotte,² M. Saltzman,² K. Garcia,² M. Sharma,¹ M. Gunasekaran,¹ M. Smith,¹ R. Bremner,¹ T. Mohanakumar.¹
¹Norton Thoracic Institute, St. Joseph's Hospital & Medical Center, Phoenix; ²Collaborative Center for Translational Mass Spectrophotometry Translational Genomics Research Institute, Phoenix.
Molecular mechanisms involved in rejection following human lung transplantation are not well understood. Goal of this study is to identify proteomic signatures in the circulating…
2018 American Transplant Congress
Long-Term HIF-1α Stabilization is Associated with Fibrosis in Rat Lung Allografts
K. Freischlag,¹ B. Ezekian,¹ P. Schroder,¹ J. Everitt,¹ J. Yoon,¹ M. Swiderska-Syn,³ W. Parker,¹ A. Diehl,¹ J. Kwun,¹ S. Knechtle.¹
¹Duke Transplant Center, Duke University, Durham, NC; ²Medical University of South Carolina, Charleston, SC.
Introduction: HIF-1α is a subunit of a heterodimeric transcription factor hypoxia-inducible factor 1 (HIF-1) and functions as a master transcriptional regulator of cellular and developmental…