Abstracts Archive - Page 776 of 1683 - ATC Abstracts

2018 American Transplant Congress
Safety and Efficacy of Sofosbuvir-Based Direct-Acting Antiviral Agents in Kidney Transplant Recipients with HCV: A Systematic Review and Meta-Analysis
X. Wang,¹ P. Tan,¹ T. Xiang,² Y. Qiu,¹ T. Song,¹ T. Lin.¹
¹Department of Urology/Institute of Urology/Organ Transplantation Center, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China; ²West China School of Clinical Medicine, Sichuan University, Chengdu, Sichuan Province, China.
Background: Outcome data on sofosbuvir (SOF)-based therapy in patients with kidney transplantation (KTx) with hepatitis C virus infection are limited with individual studies having a…
2018 American Transplant Congress
Elbasvir-Grazoprevir (Zepatier) is Effective and Safe for the Treatment of Chronic Hepatitis C (HCV) Genotype 1 Virus in the Post Kidney Transplant Patient
P. Brown, D. Venkat.
Henry Ford Hospital, Detroit.
Objective: Limited real world data exists regarding the use of direct acting antivirals (DAA) for HCV viremia in renal transplant patients, particularly those with marked…
2018 American Transplant Congress
One-Year Outcomes in Patients with Advanced Liver Fibrosis or Compensated Cirrhosis from Chronic Hepatitis C Receiving Kidney Transplant Alone
P. Brown, F. Kumssa, D. Venkat.
Henry Ford Hospital, Detroit.
Background: Hepatitis C (HCV) was difficult to treat post-kidney transplant prior to the direct acting antiviral (DAA) era. As such patients with advanced fibrosis and…
2018 American Transplant Congress
Allogeneic Mesenchymal Stem Cells as Induction Therapy Are Safe and Feasible in Renal Allografts: Pilot Results of a Multicenter Randomized Controlled Trial
Q. Sun,¹ F. Han,¹ M. Zhao,² R. Cao,³ D. Zhao,¹ Z. Huang,¹ L. Hong,¹ Y. Peng,¹ Q. Sun.¹
¹Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; ²Zhujiang Hospital, Southern Medical University, Guangzhou, China; ³Second Affiliated Hospital, Guangzhou Traditional Chinese Medicine University, Guangzhou, China.
Background: Delayed graft function (DGF) and acute rejection lead to adverse effects on graft outcomes. Optimal induction intervention should include both renal structure injury repair…
2018 American Transplant Congress
Ischemia-Free Liver Transplantation for Fatty Liver Grafts in Human
W. Ju, S. Huang, Z. Guo, G. Chen, X. He.
Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
BACKGROUND&AIMS: Fatty liver diseases have led to a continuous increase of available donor livers containing fat. Fatty liver grafts were identified as an independent risk…
2018 American Transplant Congress
Kidney Transplantation (KTx) Using Kidneys from Deceased Donors (DD) with AKIN Stage 2 and 3 Are Associated with Excellent Graft Outcomes
A. Kumar, K. Reddy, A. Srinivasan, J. Huskey, H. Khamash, M. Smith, A. Moss, R. Heilman.
Mayo Clinic, Phoenix.
BackgroundKTx from DD with AKI can be a good source of kidneys however these kidneys are underutilized. The aim of this study is to determine…
2018 American Transplant Congress
Time and Perfusate Dependent Molecular Response in Ex Vivo Lung Perfusion
P. Dromparis,¹ N. Aboelnazar,² S. Wagner,¹ S. Himmat,² C. White,² J. Luc,² D. Freed,² J. Nagendran,² M. Mengel,¹ B. Adam.¹
¹Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Canada; ²Department of Surgery (Cardiac), University of Alberta, Edmonton, Canada.
Lung transplantation has limited organ utilization and high rates of primary graft dysfunction, in part due to acute lung injury (ALI). Cold static preservation (CSP)…
2018 American Transplant Congress
Characterization of Exosomal DNA from Human Lung Transplant Recipients
S. Bansal, M. Sharma, R. Walia, R. Bremner, M. Smith, T. Mohanakumar.
Norton Thoracic Institute, St. Joseph's Hosp & Med Ctr, Phoenix.
Exosomes are small vesicles which contains biological molecules including proteins, RNA`s and miRNAs. It has been reported that exosomes may contain ds DNA originated from…
2018 American Transplant Congress
Identification of Exosomal Proteins from Human Lung Transplant Recipients
S. Bansal,¹ P. Pirrotte,² M. Saltzman,² K. Garcia,² M. Sharma,¹ M. Gunasekaran,¹ M. Smith,¹ R. Bremner,¹ T. Mohanakumar.¹
¹Norton Thoracic Institute, St. Joseph's Hospital & Medical Center, Phoenix; ²Collaborative Center for Translational Mass Spectrophotometry Translational Genomics Research Institute, Phoenix.
Molecular mechanisms involved in rejection following human lung transplantation are not well understood. Goal of this study is to identify proteomic signatures in the circulating…
2018 American Transplant Congress
Long-Term HIF-1α Stabilization is Associated with Fibrosis in Rat Lung Allografts
K. Freischlag,¹ B. Ezekian,¹ P. Schroder,¹ J. Everitt,¹ J. Yoon,¹ M. Swiderska-Syn,³ W. Parker,¹ A. Diehl,¹ J. Kwun,¹ S. Knechtle.¹
¹Duke Transplant Center, Duke University, Durham, NC; ²Medical University of South Carolina, Charleston, SC.
Introduction: HIF-1α is a subunit of a heterodimeric transcription factor hypoxia-inducible factor 1 (HIF-1) and functions as a master transcriptional regulator of cellular and developmental…