Abstracts Archive - Page 767 of 1683 - ATC Abstracts

2018 American Transplant Congress
Assessment of Bile Production and Quality during Normothermic Ex Vivo Liver Perfusion to Predict Biliary Injury
D. Kollmann,¹ I. Linares,¹ S. Ganesh,¹ R. Rosales,¹ M. Hamar,¹ P. Urbanellis,¹ A. Wiebe,¹ P. Yip,² O. Adeyi,² M. Selzner,¹ N. Selzner.¹
¹Multi Organ Transplant Program, Toronto General Hospital, Toronto, Canada; ²Laboratory Medicine and Pathobiology, University Health Network, Toronto, Canada.
Background. Liver transplantation (LT) with donation after circulatory death (DCD)-grafts is associated with higher risk for biliary strictures. We evaluated bile production and quality during…
2018 American Transplant Congress
Factors Predicting Viability Achievement on Discarded Donor Livers Submitted to Extra-Corporeal Machine Perfusion
Y. Boteon,^1,2 R. Laing,^1,2 A. Schlegel,² J. Attard,^1,2 L. Wallace,¹ A. Smith,² T. Perera,² J. Isaac,² D. Mirza,² S. Afford,¹ H. Mergental.²
¹National Institute for Health Research, Birmingham Liver Biomedical Research Centre, University of Birmingham, Institute of Immunology and Immunotherapy, Birmingham, United Kingdom; ²Liver Unit, Queen Elizabeth Hospital, University Hospitals Birmingham, Birmingham, United Kingdom.
Background: Ex-vivo machine perfusion of livers (MP) may offer superior preservation for marginal donor organs. During normothermic machine perfusion (NMP) is possible to assess liver…
2018 American Transplant Congress
Preoperative Antibiotics Treatment Decreases Endoplasmic Reticulum Stress and Protects Liver Transplant from Ischemia-Reperfusion Injury
T. Ito, F. Kaldas, K. Nakamura, S. Kageyama, A. Aziz, R. Busuttil, J. Kupiec-Weglinski.
Department of Surgery, The Dumont-UCLA Transplant Center, Los Angeles, CA.
Ischemia-reperfusion injury (IRI) represents a major risk factor of graft dysfunction in liver transplantation (LT). We have reported a critical role of endoplasmic reticulum (ER)…
2018 American Transplant Congress
A Cost Analysis on Normothermic Machine Perfusion at a Single Center
D. Pezzati, Q. Liu, H. Hassan, G. Iuppa, L. Hernandez, G. D'Amico, T. Diago Uso, B. Heghtsad, C. Miller, C. Quintini.
General Surgery, Cleveland Clinic, Cleveland, OH.
INTRODUCTION: Normothermic machine perfusion (NMP) for liver transplantation is a novel and promising technique.One of the concerns related to its usage is the high cost.The…
2018 American Transplant Congress
Pumping Donor Kidneys Reduces DGF and Improves Allograft Survival without Affecting Rejection Rates
M. Samoylova, A. Nash, T. Brennan.
Surgery, Duke University, Durham, NC.
Recent evidence suggests that hypothermic machine perfusion of donor kidneys reduces delayed graft function (DGF), but data is sparse on its effect on allograft rejection.…
2018 American Transplant Congress
Consistency of DCD Procurement Procedures across Organ Procurement Organizations – Preliminary Findings
G. Mitro,¹ A. Ortiz,² R. Warnock,³ P. Wiederhold,³ K. Jiles,³ J. Ortiz.¹
¹University of Toledo College of Medicine, Toledo, OH; ²University of California Los Angeles, Los Angeles; ³Life Connection of Ohio, Toledo, OH.
Intro: Variation among procedures across Organ Procurement Organizations (OPOs) may account for discrepancies in outcomes associated with the use of deceased after cardiac death (DCD).…
2018 American Transplant Congress
Protective Effect of Ceria-Nanoparticle on Renal Ischemia Reperfusion Injury in Rats
S-.I. Min,¹ S. Kim,² S. Kim,³ J. Ha.¹
¹Surgery, Seoul National University College of Medicine, Seoul, Korea; ²Surgery, Kangwon National University Hospital, Seoul, Korea; ³Surgery, Myongji Hospital, Goyang, Korea.
Introduction: Ischemia-reperfusion injury (IRI) is a commonly encountered problem in organ transplantation. IRI is associated with delayed graft function and acute rejection; therefore IRI adversely…
2018 American Transplant Congress
Shortened Cold Ischemia Time and Reduced Incidence of Delayed Graft Function for Kidney Transplants through Enhanced Tissue Compatibility Testing
I. Helanterä,¹ T. Saarinen,² J. Peräsaari,² M. Lempinen,¹ J. Lauronen.²
¹Transplantation and Liver Surgery, Helsinki University Hospital, Helsinki, Finland; ²Histocompatibility Laboratory, Finnish Red Cross Blood Service, Helsinki, Finland.
A. HLA-typing and prospective leukocyte cross-matching needed for deceased donor kidney transplantation (kTX) may delay the onset of surgery. We compared cold ischemia times (CIT)…
2018 American Transplant Congress
High Dose Tissue Plasminogen Activator Flush during Donation-after-Cardiac-Death (DCD) Liver Procurements Offers Optimal Outcomes
J. Torabi,² J. Graham,^1,2 S. Bellmare,^1,2 M. Kinkhabwala,^1,2 J. Rocca.^1,2
¹Montefiore Center for Transplantation, Montefiore Medical Center, Bronx, NY; ²Albert Einstein College of Medicine, Bronx, NY.
BackgroundEfforts to expand the donor pool have resulted in increased utilization of donation-after-cardiac-death (DCD) liver donors. Here we report on our experience using high dose…
2018 American Transplant Congress
Allogeneic Mesenchymal Stem Cells as Induction Therapy Are Safe and Feasible in Renal Allografts: Pilot Results of a Multicenter Randomized Controlled Trial
Q. Sun,¹ F. Han,¹ M. Zhao,² R. Cao,³ D. Zhao,¹ Z. Huang,¹ L. Hong,¹ Y. Peng,¹ Q. Sun.¹
¹Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; ²Zhujiang Hospital, Southern Medical University, Guangzhou, China; ³Second Affiliated Hospital, Guangzhou Traditional Chinese Medicine University, Guangzhou, China.
Background: Delayed graft function (DGF) and acute rejection lead to adverse effects on graft outcomes. Optimal induction intervention should include both renal structure injury repair…