ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Outcomes of Pregnancy in Simultaneous Pancreas and Kidney (SPK) Transplant Recipients

    S. Punjala1, B. L. Phillips1, P. Chowdhury1, T. Pile1, K. Harding2, C. J. Callaghan1, C. Nelson-Piercy2, M. Drage1

    1Department of Nephrology, Renal Transplant and Urology, Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom, 2Department of Obstetrics & Gynaecology, Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom

    *Purpose: The chance of successful pregnancy is low in women with end stage renal disease. In women with type-1 DM, not only are the fertility…
  • 2020 American Transplant Congress

    Membrane Expression of CD163 and CD206 by Blood Monocytes is Upregulated in Kidney Allograft Recipients

    I. Striz, L. Curnova, V. Svachova, M. Fialova, M. Novotny, O. Viklicky

    Institute for Clinical and Experimental Medicine, Prague, Czech Republic

    *Purpose: Blood monocytes differentiating into tissue macrophages or dendritic cells are involved in multiple immune responses including reactions to the transplanted allograft. Peripheral monocytes can…
  • 2020 American Transplant Congress

    Evaluation of Pretransplant Serologies and Vaccination Rates in Kidney Transplant Candidates

    S. Schneider, C. Truax, A. Carlson, B. Clark, B. Sirandas, L. Smith

    Department of Pharmacy Services, University of Utah Health, Salt Lake City, UT

    *Purpose: Assessing serologic status presents opportunities to provide live vaccinations to solid organ transplant (SOT) candidates. This is especially important given the increased risk of…
  • 2020 American Transplant Congress

    Precision Dosing for Tacrolimus Using Genotypes and Clinical Factors

    M. Al-Kofahi1, W. Oetting1, A. Israni2, D. Schladt3, W. Guan4, B. Wu4, C. Dorr5, R. Remmel6, R. Mannon7, N. Pankratz8, A. Matas9, P. Jacobson1

    1Experimental and Clinical Pharmacology, Univ of MN, College of Pharmacy, Minneapolis, MN, 2Nephrology, Univ of MN and Hennepin HealthCare, Minneapolis, MN, 3Hennepin HealthCare Research Institute, Hennepin HealthCare, Minneapolis, MN, 4Biostatistics, Univ of MN, Minneapolis, MN, 5Nephrology, Hennepin HealthCare, Minneapolis, MN, 6Medicinal Chemistry, Univ of MN, College of Pharmacy, Minneapolis, MN, 7Nephrology, Univ of Alabama, Minneapolis, MN, 8Lab Medicine Pathology, Univ of MN, Minneapolis, MN, 9Surgery, Univ of MN, Minneapolis, MN

    *Purpose: Variants in CYP3A4/5 genes, clinical factors and drug-drug interactions are associated with tacrolimus (TAC) clearance and dose. This results in high intra- and inter-…
  • 2020 American Transplant Congress

    A Single Center Experience of Atypical Hemolytic Uremic Syndrome Post Solid Organ Transplantation – “Benign Genetic Variants: Perhaps No More”

    M. Khan, M. Anand, T. Kaur, S. Bumb, S. Shah, A. Govil, B. G. Abu Jawdeh

    University of Cincinnati, Cincinnati, OH

    *Purpose: Atypical hemolytic uremic syndrome (aHUS) is a genetic-based thrombotic microangiopathy (TMA) that is mediated by the activation of the alternative complement pathway. Heterozygous deletion…
  • 2020 American Transplant Congress

    Arterial Flow, Lactate and NGAL as a Decision Making Trinity in Normothermic Kidney Preservation

    A. Weissenbacher1, M. L. Lo Faro2, C. C. Coussios2, P. J. Friend2

    1Visceral, Transplant and Thoracic Surgery, Innsbruck Medical University, Innsbruck, Austria, 2University of Oxford, Oxford, United Kingdom

    *Purpose: The aim of our study was to investigate biomarkers in a blood-based perfusate of normothermically perfused discarded human kidneys using urine recirculation as a…
  • 2020 American Transplant Congress

    Public Information Needs about VCA Donation and Transplantation in the United States

    H. Sung1, A. Ferzola1, J. Uriarte2, N. Anderson2, C. Cooney1, G. Brandacher1, E. Gordon2, M. Henderson1

    1Johns Hopkins University, Baltimore, MD, 2Northwestern University, Evanston, IL

    *Purpose: Vascularized Composite Allotransplantation (VCA) involves transplantation of multiple tissues (e.g., skin, muscle, bone, nerves, blood vessels, etc.) as a structural unit from a donor…
  • 2020 American Transplant Congress

    Urinary APOA4 as a Biomarker for Chronic Renal Allograft Injury and Rapid Renal Function Decline in Kidney Transplant Recipients

    H. Jeon1, D. Shin1, J. Oh1, J. Park2, K. Ko3, J. Kim3, S. Lee3

    1Department of Internal Medicine, Hallym University College of Medicine, Kangdong Sacred Heart Hospital, Seoul, Korea, Republic of, 2Department of Laboratory Medicine, Hallym University College of Medicine, Kangdong Sacred Heart Hospital, Seoul, Korea, Republic of, 3Department of Surgery, Hallym University College of Medicine, Kangdong Sacred Heart Hospital, Seoul, Korea, Republic of

    *Purpose: Chronic renal allograft injury (CRAI) remains a major cause of allograft loss in kidney transplant recipients (KTRs). The aim of this study was to…
  • 2020 American Transplant Congress

    T Cell Dysfunction as Measured by Impaired Antigen Response is Associated with Infection and Frailty in Kidney Transplant Recipients

    J. Schaenman, M. Rossetti, V. Groysberg, G. Sunga, E. Liang, S. Bunnapradist, E. Reed

    David Geffen School of Medicine at UCLA, Los Angeles, CA

    *Purpose: Kidney transplant recipients are at risk for infection, especially the growing numbers of older patients. Our previous studies demonstrated that senescent and exhausted T…
  • 2020 American Transplant Congress

    Accelerated Decline in Glomerular Density: An Unrecognized Pathologic Process after Kidney Transplantation

    A. Denic, B. H. Smith, W. D. Park, M. V. Luhman, M. P. Alexander, A. D. Rule, M. D. Stegall

    Mayo Clinic, Rochester, Rochester, MN

    *Purpose: Studies in healthy adults have shown that glomerular density slowly declines with older age (-0.5% per decade), and globally sclerotic glomeruli (GSG) slowly increase…
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