ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Transplantation from Donors with Positive Blood Culture

    H. Mo, S. Min, H. Ko, C. Chung, H. Kim, A. Han, J. Ha

    Department of Surgery, Seoul National University Hospital, Seoul, Korea, Republic of

    *Purpose: The use of organs from donors with infection is limited because of the possibility of transmission. Herein we report our experience of transplantation from…
  • 2020 American Transplant Congress

    Real-World Experiences in the Transplantation of Hepatitis C Positive Kidneys

    J. M. Steinbrink, J. Byrns, L. Crona, M. Ellis, S. Sanoff, E. K. Maziarz, C. R. Wolfe

    Duke University, Durham, NC

    *Purpose: With advancements of direct-acting antivirals, transplantation of HCV-NAT+ (HCV+) organs to HCV-negative (HCV-) recipients has been used to decrease wait times without apparent sacrifice…
  • 2020 American Transplant Congress

    Effect of Everolimus and Reduced Calcineurin Inhibitors on Biopsy Proven BK Virus Associated Nephropathy

    Z. S. Zaky, M. Spinner, B. Stephany, S. Nurko, R. Fatica, J. Augustine, E. Poggio

    Cleveland Clinic, Cleveland, OH

    *Purpose: BK virus-associated nephropathy (BKVAN) is a clinically important entity that contributes to allograft loss in kidney transplant recipients (KTRs). Mammalian target of rapamycin inhibitors…
  • 2020 American Transplant Congress

    Viral Kinetics of De Novo HCV Infection and Response to Antiviral Therapy in Liver and Kidney Transplant Recipients Receiving HCV-Viremic Donors

    N. Terrault1, J. Burton2, E. Verna3, C. Mobley4, D. Victor4, J. Trotter5, C. Niemann6, R. Rubin7

    1University of Southern California, Los Angeles, CA, 2UC, Denver, CO, 3Columbia Universeity, New York, NY, 4Houston Methodist, Houston, TX, 5Baylor University, Dallas, TX, 6UCSF, San Francisco, CA, 7Piedmont Atlanta Hosptial, Atlanta, GA

    *Purpose: There is general agreement that expanded use of organs from HCV-viremic donors is desirable, including in recipients without HCV infection. However, the optimal treatment…
  • 2020 American Transplant Congress

    Evaluation of Cytomegalovirus Prophylaxis in Low and Intermediate Risk Kidney Transplant Recipients Receiving Lymphocyte-Depleting Induction

    H. Stamps, K. Linder, D. O'Sullivan, F. Cheema, H. Kutzler

    Hartford Hospital, Hartford, CT

    *Purpose: This study evaluates if choice and duration of Cytomegalovirus (CMV) prophylaxis based on donor (D) and recipient (R) CMV serostatus impacts the incidence of…
  • 2020 American Transplant Congress

    BK Viremia: A Double Edged Sword – The Impact of Immunosuppression Reduction on Allograft Rejection

    A. Szczepanik1, A. Bixby1, C. Burrelli1, A. Padiyar2, T. Srinivas2, K. Chavin3

    1Pharmacy, University Cleveland Medical Center, Cleveland, OH, 2Nephrology, University Cleveland Medical Center, Cleveland, OH, 3Surgery, University Cleveland Medical Center, Cleveland, OH

    *Purpose: BK viremia (BKV) increases the risk of renal allograft loss following transplant. Guidelines recommend reduction of immunosuppression (IS) after BKV diagnosis, however, the ideal…
  • 2020 American Transplant Congress

    Immune Checkpoint Inhibitor Use in Kidney Transplant Recipients: Rejection Risk, Prevention and Transcriptional Signature in Allograft

    N. Murakami1, G. Reid2, A. Weins1, B. Adam2, M. Mengel2, L. Riella1

    1Brigham and Women's Hospital, Boston, MA, 2University of Alberta, Edmonton, AB, Canada

    *Purpose: Immune checkpoint inhibitor (ICI) use has changed the landscape of cancer treatment. Several cases of acute rejection in use of ICI have been reported,…
  • 2020 American Transplant Congress

    Contrary to Expectation, the Use of Immune Checkpoint Inhibitors is Not Consistently Associated with Early Onset Allograft Rejection in Solid Organ Transplant Recipients

    I. Owoyemi1, C. M. Costello2, C. Thongprayoon1, S. Markovic3, H. Joerg4, C. C. Otley5, T. Taner6, A. R. Mangold2, N. Leung1, S. Herrmann1, A. Kukla1

    1Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, 2Department of Dermatology, Mayo Clinic, Scottsdale, AZ, 3Division of Medical Oncology, Mayo Clinic, Rochester, MN, 4Department of Cardiology, Mayo Clinic, Rochester, MN, 5Department of Dermatology, Mayo Clinic, Rochester, MN, 6Departments of Surgery & Immunology, Mayo Clinic, Rochester, MN

    *Purpose: Immune checkpoint inhibitors (ICIs) have revolutionized cancer therapy but are generally avoided in solid organ transplant recipients (SOTRs) due to concern for allograft rejection…
  • 2020 American Transplant Congress

    Comparative Analysis of Risk Factors and Outcomes in Kidney Transplant Recipients with Lung Cancer and Those with No Malignancy: UNOS Data Set

    H. Patel1, V. Nissaisorakarn2, E. Sula Karrecci1, N. Agrawal1, F. Cardarelli1

    1Transplant Nephrology, Beth Israel Deaconess Medical Center, Boston, MA, 2Department of Internal Medicine, Metrowest Medical Center, Boston, MA

    *Purpose: Transplant recipients are at increased risk for malignancy. Patients who develop cancer after transplant have worse outcomes, especially those with lung cancer. Transplant-related risk…
  • 2020 American Transplant Congress

    Clinical Features and Transplant Outcomes in Kidney Transplant Recipients with Renal Cell Carcinoma

    C. Baek, H. Kim, S. Park

    Asan Medical Center, Seoul, Korea, Republic of

    *Purpose: Previous studies have recommended a 2-5-year waiting time prior to kidney transplantation (KT) in patients with end-stage renal disease (ESRD) and symptomatic renal cell…
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