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American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    The Role of Complement-Split Products as Biomarkers for Acute Antibody-Mediated Rejection of Kidney Allografts

    B. G. Abu Jawdeh1, B. Campos-Naciff1, K. Harrison1, K. Meganathan1, A. Kumar2, M. Anand1, A. Govil1, E. S. Woodle1, B. P. Dixon3

    1University of Cincinnati, Cincinnati, OH, 2All India Institute of Medical Sciences, New Delhi, India, 3University of Colorado, Aurora, CO

    *Purpose: Acute antibody-mediated rejection (AMR) is mediated by the activation of the classical complement system in addition to non-complement dependent inflammatory pathways. Complement fixation by…
  • 2020 American Transplant Congress

    Characterization of an Integrative Prognostic Score for US Patients Taken from the DART Study

    J. Bromberg1, R. Bloom2, P. Sood3

    1University of Maryland, Baltimore, MD, 2Penn Medicine, Philadelphia, PA, 3University of Pittsburgh Medical Center, Pittsburgh, PA

    *Purpose: iBox is a validated cloud-based software as a service (SaaS) algorithm that provides a predictive analysis of the post-transplant patient, quantifying the risk of…
  • 2020 American Transplant Congress

    Epidemiology of Non-Aspergillus Mold in Lung Transplant Recipients at a Large Transplant Center

    J. A. Morillas1, F. J. Marco Canosa1, H. Hassouna2, K. Brizendine1

    1Infectious Disease, Cleveland Clinic Foundation, Cleveland, OH, 2Infectious Disease, Spectrum Health Medical Group-Michigan State University College of Human Medicine, Grand Rapids, MI

    *Purpose: Invasive fungal infections (IFI) remain a significant cause of mortality among lung transplant recipients (LTR). The emergence of non-Aspergillus molds has become a concern…
  • 2020 American Transplant Congress

    Donor-Derived Cell-Free DNA May Not Discriminate Rejection in Kidney Transplant Recipients with a Prior Allograft in Place

    A. Vo, M. Gillespie, S. C. Jordan, A. Peng, R. Najjar, S. Sethi, K. Lim, N. Ammerman, E. Huang

    Cedars-Sinai, Los Angeles, CA

    *Purpose: Donor-derived cell-free DNA (dd-cfDNA) is an injury biomarker discriminating rejection in kidney transplant (KTx) patients (pts). However, its performance when stratified by rejection risk…
  • 2020 American Transplant Congress

    Simultaneously Detection of ddcfDNA in Plasma and Urine Assist to Determine the Type of Rejection in Renal Transplant Patients

    D. Cheng1, F. Liu2, H. Liu2, T. Jiang2, Y. Zhou3, L. Shu2, X. Li1, K. Xie1, X. Ni1, J. Chen1, J. Ge2, Z. Liu1, H. Shi3

    1Jinling Hospital Nanjing University, Nanjing, China, 2AlloDx, Shanghai; Suzhou, China, 3Jiangsu University, Zhenjiang, China

    *Purpose: The correct diagnosis and treatment of acute rejection (ABMR and TCMR) are the key to the long-term survival after renal transplantation. Renal biopsy is…
  • 2020 American Transplant Congress

    The Plasma DdcfDNA Level Associates with the Pathological Characteristics in Renal Allograft

    R. Wang, J. Shen, J. Wu, J. Chen

    Kidney Disease Center, First Affiliated Hospital of Zhejiang University, Hangzhou, China

    *Purpose: Donor-derived cell-free DNA (ddcfDNA) is a promising biomarker for monitoring the allograft health status, however, its relationship with the pathological characteristics is still elusive.*Methods:…
  • 2020 American Transplant Congress

    The Frequency of De Novo DSA in the Years Following Heart Transplantation

    A. Shen, J. Patel, M. Kittleson, D. Chang, E. Kransdorf, D. Geft, K. Nishihara, L. Czer, F. Esmailian, J. A. Kobashigawa

    Cedars-Sinai Smidt Heart Institute, Los Angeles, CA

    *Purpose: The timing of the development of donor specific antibody (DSA) after heart transplantation is not clear. De novo DSA has been reported to be…
  • 2020 American Transplant Congress

    Donor-Derived Cell-Free DNA Levels During Early Rejection after Kidney Transplant May Be Impacted by Type of Induction Agent Received

    M. Gillespie, K. Lim, A. Vo, E. Huang, N. Ammerman, A. Peng, R. Najjar, S. Sethi, S. Jordan

    Cedars-Sinai, Los Angeles, CA

    *Purpose: Donor-derived cell-free DNA (dd-cfDNA) is an injury biomarker that detects rejection in kidney transplant recipients (KTR). It is reported as % cfDNA from the…
  • 2020 American Transplant Congress

    Incidence of Fragility Fractures and Changes in Bone Mineral Density in Type 1 Diabetes Recipients of Pancreas Transplant Alone

    Y. C. Kudva, S. Batthula, R. Kaur, B. H. Smith, S. R. Rizvi, P. G. Dean, W. K. Kremers, M. D. Stegall, R. A. Wermers

    Mayo Clinic, Rochester, MN

    *Purpose: Type 1 Diabetes (T1D) is associated with increased fracture risk. Solid organ transplant recipients are at high risk for fracture but limited data are…
  • 2020 American Transplant Congress

    Resilience in Heart Transplant Candidates

    Y. T. Bui1, D. S. Yip2, B. W. Hardaway3, S. M. Dunlay4, S. Jowsey-Gregoire5, R. Benzo6, R. C. Daly7, M. A. Hathcock8, K. Thompson9, C. C. Kennedy10

    1Mayo Clinic Alix School of Medicine, Rochester, MN, 2Department of Transplantation, Mayo Clinic, Jacksonville, FL, 3Division of Cardiovascular Diseases, Mayo Clinic, Scottsdale, AZ, 4Department of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, 5Department of Psychiatry, Mayo Clinic, Rochester, MN, 6Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN, 7Division of Cardiovascular Surgery, Mayo Clinic, Rochester, MN, 8Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, 9Pulmonary Clinical Research Unit, Mayo Clinic, Rochester, MN, 10William J. von Liebig Center for Transplantation and Regenerative Medicine, Mayo Clinic, Rochester, MN

    *Purpose: Resilience is the capacity to adapt to or recover from adverse experiences. Our objective was to measure resilience in waitlisted, adult heart transplant candidates…
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