Abstracts Archive - Page 325 of 1683 - ATC Abstracts

2021 American Transplant Congress
Combined Impact of Pre-sensitization and Delayed Graft Function on Allograft Rejection in Deceased Donor Kidney Transplantation: A Nationwide Cohort Study
H. Lee¹, Y. Park¹, T. Ban², S. Song³, S. Song⁴, J. Yang⁵, C. Ahn⁵, C. Yang¹, B. Chung¹
¹Division of Nephrology, Department of Internal Medicine, Seoul St. Mary’s hospital, Seoul, Korea, Republic of, ²Division of Nephrology, Department of Internal Medicine, Eunpyeong St. Mary’s hospital, Seoul, Korea, Republic of, ³Organ Transplantation Center and Department of Internal Medicine, Pusan National University Hospital, Pusan, Korea, Republic of, ⁴Department of Surgery, Ewha Womans University Medical Center, Seoul, Korea, Republic of, ⁵Department of Nephrology, Seoul National University Hospital, Seoul, Korea, Republic of
*Purpose: The aim of this study is to investigate whether or not delayed graft function (DGF) and pre-transplant sensitization has a synergistic adverse effect on…
2021 American Transplant Congress
Plasma Donor-Derived Cell-Free DNA Levels Risk-Stratify Kidney Allograft Injury with Isolated Transplant Glomerulitis
L. Bu¹, S. Anand², A. Pai³, J. S. Bromberg⁴, G. Gupta⁵, I. Moinuddin⁵, T. Alhamad⁶, V. Bowers⁷, S. Ghosh⁸, W. Tian⁸, E. Stites⁹
¹University of Minnesota, Minneapolis, MN, ²Intermountain Medical Center, Murray, UT, ³University of Texas McGovern Medical School, Houston, TX, ⁴University of Maryland School of Medicine, Baltimore, MD, ⁵Virginia Commonwealth University, Richmond, VA, ⁶Washington University in St. Louis, St. Louis, MO, ⁷Tampa General Hospital, Tampa, FL, ⁸CareDx, Brisbane, CA, ⁹University of Colorado, Aurora, CO
*Purpose: The Banff lesion Glomerulitis (g) characterizes the degree of microvascular glomerular inflammation. Some studies have demonstrated glomerulitis in the absence of C4d in association…
2021 American Transplant Congress
Long Term Safety and Efficacy of Tocilizumab (anti-il6r, Tcz) Therapy in the Treatment of Refractory Chronic Antibody Mediated Rejection (cabmr) in 25 Pediatric Renal Transplant Recipients
M. Pearl¹, P. Weng¹, A. Dokras², H. Pizzo³, J. Garrison³, C. Butler¹, J. Q. Zhang¹, K. Lim³, E. Reed¹, I. Kim³, M. Haas³, X. Zhang³, R. Ettenger¹, S. Jordan³, D. Puliyanda³
¹Pediatric Nephrology, UCLA Medical Center, Los Angeles, CA, ²Pediatric Nephrology, UT South Western, Dallas, CA, ³Pediatric Nephrology, Cedars Sinai Medical Center, West Hollywood, CA
*Purpose: Development of de novo donor specific antibodies (DSA) post renal transplantation puts pediatric patients at risk for chronic Antibody Mediated Rejection (cABMR) and allograft…
2021 American Transplant Congress
NASH-Related HCC is Associated with Lower Rates of Post-Transplant HCC Recurrence: A Large Database Analysis
P. J. Altshuler, R. Lamm, K. Patel, H. Dang, O. Shaheen, A. P. Shah, J. Glorioso, C. G. Ramirez, A. M. Frank, W. R. Maley, A. S. Bodzin
Department of Surgery, Thomas Jefferson University, Philadelphia, PA
*Purpose: As incidence of hepatocellular carcinoma (HCC) and Non-Alcoholic Steatohepatitis (NASH) increase, NASH-related HCC is an increasingly common transplant indication. Large-scale studies evaluating transplantation for…
2021 American Transplant Congress
Adjuvant Immunotherapy for Liver Transplant Recipients with Hepatocellular Carcinoma Using Donor Liver-derived Natural Killer Cells
M. Ohira¹, R. Hotta¹, Y. Imaoka¹, K. Sato¹, N. Tanimine¹, Y. Tanaka¹, S. Nishida², A. Tzakis², H. Ohdan¹
¹Hiroshima University, Hiroshima, Japan, ²University of Miami, Miami, FL
*Purpose: Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide and is an indication for liver transplantation (LT). Immunosuppressive regimens currently used after…
2021 American Transplant Congress
Kidney Transplant Recipients Who Had Covid-19 Prior to Transplant: A Single-center Experience
S. Sultan, M. Aull, R. Craig-Schapiro, E. C. Liu, J. H. Lee, S. Kapur
New York Presbyterian / Weill Cornell, New York, NY
*Purpose: In the early recovery phase after the initial surge of the COVID-19 pandemic, a question emerged in the context of resuming transplant activity: should…
2021 American Transplant Congress
Predictors of Severe Covid-19 in Kidney Transplant Recipients in the First and Second Waves: Analysis of the Spanish Registry
M. Crespo¹, A. Mazuecos², I. Pérez-Flores³, F. Moreso⁴, A. Andrés⁵, C. Jimenez⁶, M. Molina⁷, C. Canal⁸, L. Sánchez-Cámara⁹, S. Zárraga¹⁰, M. Ruiz Fuentes¹¹, M. Aladrén¹², E. Melilli¹³, V. López¹⁴, E. Sanchez¹⁵, J. Pascual for Spanish Nephro Society Covid-Registry¹
¹Nephrology, Hospital del Mar, Barcelona, Spain, ²Nephrology, Hospital Puerta del Mar, Cadiz, Spain, ³Nephrology, Hospital Clinico San Carlos, Madrid, Spain, ⁴Nephrology, Hospital Valle Hebrón, Barcelona, Spain, ⁵Nephrology, Hospital 12 Octubre, Madrid, Spain, ⁶Nephrology, Hospital La Paz, Madrid, Spain, ⁷Nephrology, Hospital Germans Trias i Pujol, Barcelona, Spain, ⁸Nephrology, Fundacio Puigvert, Barcelona, Spain, ⁹Nephrology, Hospital Gregorio Marañón, Madrid, Spain, ¹⁰Nephrology, Hospital de Cruces, Bilbao, Spain, ¹¹Nephrology, Hospital Virgen de las Nieves, Granada, Spain, ¹²Nephrology, Hospital Miguel Servet, Zaragoza, Spain, ¹³Nephrology and Kidney Transplantation, Hospital de Bellvitge, Barcelona, Spain, ¹⁴Nephrology, Hospital Regional de Málaga, Malaga, Spain, ¹⁵Nephrology, Hospital de Cabueñes, Gijon, Spain
*Purpose: To better know the impact and characteristics of Covid-19 in renal patients, the Spanish Society of Nephrology set up a voluntary registry in March,…
2021 American Transplant Congress
Drivers of Graft Failure in Pediatric Kidney Transplant Change Over Time
E. Benz¹, D. Schaubel², S. Amaral¹
¹Children's Hospital of Philadelphia, Philadelphia, PA, ²Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania, Philadelphia, PA
*Purpose: Short-term pediatric kidney transplant outcomes have improved over time with advanced surgical techniques and better immunosuppression, but long-term graft outcomes remain suboptimal - concerning…
2021 American Transplant Congress
A Randomized, Multicenter, Blinded Study Assessing the Effects of Gaseous Nitric Oxide in an Ex Vivo System of Human Lungs
M. G. Hartwig¹, J. A. Klapper¹, N. Poola², A. Banga³, P. G. Sanchez⁴, J. S. Murala³, J. L. Potenziano²
¹Duke University Medical Center, Durham, NC, ²Mallinckrodt Pharmaceuticals, Bedminster, NJ, ³University of Texas Southwestern Medical Center, Dallas, TX, ⁴University of Pittsburgh Medical Center, Pittsburgh, PA
*Purpose: The effects of nitric oxide (NO) on donor lungs during ex vivo lung perfusion (EVLP) have not been studied. We assessed whether the novel…
2021 American Transplant Congress
Perioperative Blood Transfusion is Associated with the Development of New HLA Antibodies After Adult Lung Transplantation
A. Hicks¹, A. Stoker², M. Cooter², A. Ali³, J. Klapper⁴, J. Poisson⁵, D. Chen⁵, J. Haney⁴, K. Ghadimi², M. Hartwig⁴, I. Welsby², B. Bottiger²
¹Anesthesiology, Duke University Hospital, South Portland, ME, ²Anesthesiology, Duke University Hospital, Durham, NC, ³Pulmonology, Allergy and Critical Care Medicine, Duke University Hospital, Durham, NC, ⁴Cardiothoracic Surgery, Duke University Hospital, Durham, NC, ⁵Pathology, Duke University Hospital, Durham, NC
*Purpose: Lung transplant (LT) recipients who develop new antibodies to human leukocyte antigen (HLA) have associated with chronic lung allograft dysfunction and worsened outcomes. We…