ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Intragraft Gene Expression Profiles of C4d-/DSA+ and C4d-/DSA- Transplant Glomerulopathy Biopsies Compared to Biopsies with Chronic Antibody Mediated Rejection

    N. Hayde, Y. Bao, J. Pullman, G. De Boccardo, M. Lubetzky, E. Akalin

    Montefiore/Einstein Transplant Center, Bronx, NY

    Background: We investigated the histopathologic features and gene expression profiles of C4d-/donor-specific anti-HLA antibodies (DSA)+ and C4d-/DSA- transplant glomerulopathy (TGP) biopsies compared to C4d+/DSA+ chronic…
  • 2013 American Transplant Congress

    Intra-Graft Expression of Transcripts for Endothelial Activation and NK Cell Markers, Detected by Real-Time qPCR, Is Associated with the Presence of Donor Specific Antibodies, and Identifies Kidney Transplants at Risk of Failure

    A. McLean, K. Dominy, H. De Kort, P. Brookes, J. Behmoaras, J. Galliford, C. Roufosse, T. Cook, M. Willicombe, D. Taube

    Imperial College Kidney & Transplant Centre, Hammersmith Hospital, London, United Kingdom; Department of Medicine, Imperial College, London, United Kingdom

    Background: Transcriptome analysis by micro-array from kidney transplant biopsy cores has identified genes associated with endothelial activation (ENDAT), and NK cell activity (NK), which are…
  • 2013 American Transplant Congress

    Technical Variant Liver Transplantation or Whole Liver Transplantation for Pediatric Patients? A Meta-Analysis

    Z. Guo, W. Ju, Y. Wang, X. He

    Organ Transplant Center, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China

    Background: Pediatric liver transplantation has become the standard treatment for children suffering from end-stage liver disease. To overcome the shortage of appropriate-sized whole liver for…
  • 2013 American Transplant Congress

    Effect of Gender on Transplant Outcomes: A Meta-Analysis, The

    Z. Guo, W. Ju, P. Wang, M. He, S. Deng, X. He

    Organ Transplant Center, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China

    Purpose: Although the effects of donor-recipient gender matching on transplant outcomes have been discussed for long, no widely-accepted consensus has been reached. We conducted a…
  • 2013 American Transplant Congress

    Dynamic Dual Role of IL-2 Signaling in the Two-Step Differentiation Process of Adaptive Regulatory T Cells, A

    Z. Guo, Y. Miyahara, G. Wang, M. Khattar, P. Schroder, X. He, W. Chen, S. Stepkowski

    Organ Transplant Center, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China; Department of Medical Microbiology and Immunology, University of Toledo College of Medcine, Toledo; Diabetes and Endocrinology Research Center, Baylor College of Medicine, Houston; Department of Cardiovascular Surgery, Union Hospital, Huazhong University of Science and Technology, Wuhan, China

    Background. Regulatory T (Treg) cells are with potential to induce transplant tolerance. However, the molecular mechanism of the extrathymic generation of adaptive CD4+Foxp3+ regulatory T…
  • 2013 American Transplant Congress

    1-Year Outcomes of a Prospective, Open Label, Randomized, Controlled Trial of Standard vs Extended-Release Tacrolimus as Maintenance Monotherapy in Kidney Transplantation after Alemtuzumab Induction with Rapid Steroid Withdrawal (TAESR Trial)

    A. McLean, K. Chan, J. Galliford, D. Goodall, R. Charif, M. Willicombe, C. Roufosse, T. Cook, D. Taube

    Imperial College Kidney & Transplant Centre, Hammersmith Hospital, London, United Kingdom; Imperial Clinical Trials Unit, Imperial College, London, United Kingdom; Department of Medicine, Imperial College, London, United Kingdom

    Background: Extended-release (ER, once daily) tacrolimus (Advagraf) has been shown to provide equivalent results to standard-release (SR, twice daily) tacrolimus in several regimens for maintenance…
  • 2013 American Transplant Congress

    Influence of HLA Class II Donor-Specific Antibodies Present at the Time of Renal Transplantation on Early Graft Outcome, The

    C. Bryan, A. Gupta, D. Murillo, C. Wang, S. Yarlagadda, A. Nawabi, T. Schmitt

    Midwest Transplant Network, Westwood, KS; Kansas University Medical Center, Kansas City, KS; Research Medical Center, Kansas City, MO

    Introduction. HLA class II donor-specific antibodies (DSA's) have been associated with transplant glomerulopathy and ultimate graft loss. Despite these data, it is unclear if all…
  • 2013 American Transplant Congress

    MELD Score Does Not Predict Outcome of Living Donor Liver Transplantation

    K. Tomiyama, T. Kaido, Y. Ogura, K. Hata, A. Yoshizawa, S. Uemoto

    Hepato-Biliary-Pancreatic and Transplant Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan

    BackgroundLiving donor liver transplantation (LDLT) is the established treatment for the patients with end stage liver disease. Model for End-stage Liver Disease (MELD) score is…
  • 2013 American Transplant Congress

    Subnormothermic Machine Perfusion Improves Preservation of Kidneys from Non-Heart-Beating-Donors

    D. Hoyer, S. Swoboda, A. Gallinat, B. Lüer, A. Paul, T. Minor

    Department for General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany; Surgical Research Division, University Hospital Bonn, Bonn, Germany

    Introduction:Machine perfusion for preservation of donated organs led to compelling success for the outcome of renal transplantation. Though, further refinements of methods to decrease ischemia…
  • 2013 American Transplant Congress

    Prevalence and Outcomes of Pulmonary Embolism in Patients with Kidney Transplant

    A. Sakhuja, J. Schold, D. Deitzer, B. Stephany

    Nephrology and Hypertension, Cleveland Clinic, Cleveland, OH

    Prevalence and Outcomes of Pulmonary Embolism in Patients with Kidney TransplantAnkit Sakhuja MD, Jesse D Schold PhD, Diana Deitzer DO, Brian Stephany MDIntroduction: This study…
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