ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    DNA Binding Transcription Factors STAT3, PU.1 and CEBPα Cooperate in Regulating the Expression of the Inflammatory Biomarker CCL2 in Human Hepatocytes

    N. Sarma, V. Tiriveedhi, J. Crippin, W. Chapman, T. Mohanakumar

    Washington University School of Medicine, St. Louis, MO

    Background: CCL2 is a cytokine of the CC chemokine family primarily secreted by monocytes, macrophages and dendritic cells. CCL2 has been shown to be elevated…
  • 2013 American Transplant Congress

    Nesiritide Use in Adult Heart Transplant Recipients with Early Acute Kidney Injury: 6 Month Follow-Up

    M. Molina, E. Ticehurst, T. Claridge, Y. Quiaoit, J. La Joie, J. Cervino, L. Goldberg

    Heart Failure and Cardiac Transplant, Hospital of the University of Pennsylvania, Philadelphia, PA; Pharmacy, Hospital of the University of Pennsylvania, Philadelphia, PA

    Purpose: Nesiritide (rhBNP), B-type natriuretic peptide is known to reduce endothelin levels, cause afferent arteriole vasodilatation, increase natriuresis & diuresis. We hypothesize that rhBNP infusion…
  • 2013 American Transplant Congress

    Hepatitis C Virus Induced Changes in miRNA-449a Modulates the Expression of the Inflammatory Biomarker CCL2 through IL6 Receptor

    N. Sarma, V. Tiriveedhi, J. Crippin, W. Chapman, T. Mohanakumar

    Washington University School Medicine, St. Louis, MO

    Background: Hepatitis C virus (HCV) infection and the resulting liver diseases are a major health problem both in the United States and worldwide. The natural…
  • 2013 American Transplant Congress

    Liver Transplant (OLT) Length of Stay (LOS) 2000-2010: An Analysis of the UNOS/OPTN Database

    D. Kelly, J. Hammel, J. Fung

    General Surgery, Cleveland Clinic, Cleveland, OH

    Aim: To define regional patterns in post OLT LOS.Methods: Using the UNOS database (06/2011) we reviewed data on 65,891 OLT recipients, 01/2000-12/2010. Patients excluded (n=11,784)…
  • 2013 American Transplant Congress

    Early and Late Reuse of Liver Allografts from Brain-Dead Liver Transplant Recipients

    C. Desai, K. Shetty, K. Khan, R. Girlanda, C. Matsumoto, T. Fishbein

    Transplant Surgery, Medstar Georgetown transplant Institute, Washington, DC

    A unique method of donor pool expansion is the retransplantation of livers from recipients who die (brain-death). The hesitancy to reuse livers is in part…
  • 2013 American Transplant Congress

    New Proposed National Allocation Policy for Deceased Donor Kidneys in the U.S. and Its Possible Impact on Patient Outcomes

    A. Israni, S. Gustafson, N. Salkowski, K. Lamb, J. Friedewald, R. Formica, J. Snyder, B. Kasiske

    Scientific Registry of Transplant Recipients, Minneapolis Medical Research Foundation, Minneapolis, MN; Northwestern University, Chicago, IL; Yale University, New Haven, CT

    Introduction:The Organ Procurement and Transplantation Network (OPTN) has proposed a new national kidney allocation policy. Its important features include: allocating kidneys in the top twentieth…
  • 2013 American Transplant Congress

    Does Living Donor–Recipient Age Difference Matter in Long Term Outcome of Kidney Transplantation? Implication for Kidney Paired Donation

    V. Kute, A. Vanikar, M. Gumber, H. Patel, P. Shah, D. Engineer, P. Modi, J. Rizvi, V. Shah, H. Trivedi

    IKDRC-ITS, Ahmedabad, Gujarat, India

    BackgroundKidney Paired Donation (KPD) is a rapidly growing modality for facilitating living donor renal transplantation (LDRTx) for patients who are incompatible with their healthy living…
  • 2013 American Transplant Congress

    Impact of Donor Age on Three-Year Outcomes in Recipients of Extended Criteria Kidneys Treated with Belatacept vs Cyclosporine in BENEFIT-EXT Trial

    K. Budde, J. Morales, G. Blancho, F. Muehlbacher, F. Lehner, K. Rice, L. Pupim, S. Aigner, F. Vincenti

    Charité Univ Berlin, Germany; Hosp 12 de Octubre Madrid, Spain; Univ Hosp Nantes, France; Med Univ Vienna, Austria; Med Hochschule Hannover, Germany; Baylor Univ Med Ctr, TX; BMS, NJ; BMS, France; UCSF, CA

    Introduction: Belatacept (bela) was associated with improved renal function & similar pt/graft survival & AR rates vs CsA through 3 yrs follow-up in BENEFIT-EXT, the…
  • 2013 American Transplant Congress

    Eculizumab Therapy for Chronic Antibody-Mediated Injury in Kidney Transplantation: An Interim Assessment

    S. Kulkarni, N. Kirkles-Smith, R. Tomlin, R. Formica, G. Moeckel, J. Pober

    Surgery, Yale University School of Medicine, New Haven, CT; Immunobiology, Yale University School of Medicine, New Haven, CT; Medicine, Yale University School of Medicine, New Haven, CT; Pathology, Yale University School of Medicine, New Haven, CT

    Purpose: Development of de novo donor specific antibody (DSA) following kidney transplantation is associated with worse graft survival. It is generally assumed that DSA binds…
  • 2013 American Transplant Congress

    Impact of Pre-Existing and New Onset Diabetes on Hepatitis C Recurrence Following Liver Transplant, The

    K. Morbitzer, D. Taber, J. Fleming, N. Pilch, H. Meadows, C. Jordan, C. Makowski, A. Mardis, C. Bratton, P. Baliga, K. Chavin, J. McGillicuddy

    Pharmacy, MUSC, Charleston, SC; Surgery, MUSC, Charleston, SC

    Background: Hepatitis C (HCV) is the leading indication for liver transplantation in the United States. HCV recurrence after transplant is universal with several factors, including…
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