2013 American Transplant Congress
Critical Role of Notch-2 Signaling in Alloantibody Production
The role of B cells in the alloimmune response is increasingly recognized, while alloantibody production remains a major barrier to the improvement of long-term graft…2013 American Transplant Congress
Bilirubin Improvement Correlates with 90-Day Survival with Use of the ELAD® System in a Randomized, Controlled Study of Subjects with Acute Alcoholic Hepatitis or Acute Decompensation of Cirrhosis
Mary Lea Johnson Richards Organ Transplantation Center, NYU SOM, New York, NY
Background: ELAD, a human cell-based liver support system, circulates ultrafiltrated patient plasma through a hollow fiber cartridge containing active immortalized C3A human liver cells. Studies…2013 American Transplant Congress
Influenza Vaccination and Humoral Alloimmunity in Solid Organ Transplant Recipients
Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
Background: Annual influenza vaccination is usually recommended in solid-organ transplant (SOT) recipients. However, concerns have been raised about the impact of vaccination on alloimmunity. We…2013 American Transplant Congress
Carbapenem Resistant Klebsiella Pneumoniae (CRKP) Infection in Solid Organ Transplant Recipients (SOT): A Single Center Analysis
BACKGROUND: The incidence of Multi-drug-resistant bacterial infections among SOT recipients is steadily increasing. Aim of the present is to describe the epidemiology and outcome of…2013 American Transplant Congress
Inflammatory Bowel Disease in Renal Transplant Recipients: A Retrospective Multicenter Study
Inflammatory bowel disease (IBD) can occur before or, despite corticoids and immunosuppressive treatment, after transplantation. We collected characteristics of cases of IBD in renal transplant…2013 American Transplant Congress
Multi-Center, International Registry of Cardiac Transplantation for Light Chain (AL) and Transthyreitin (TTR) Amyloidosis, A
BackgroundAL and TTR cardiac amyloid has a median survival of only 6-8 months, untreated. Orthotopic heart transplant (OHT) followed by stem cell transplant (SCT) for…2013 American Transplant Congress
IL-1 Receptor Antagonist Treatment Rescues Impact of Brain Death Related Inflammation in Liver of Non-Human Primates
University of Wisconsin, Madison
Donor liver quality is critical to avoid primary non-function or dysfunction after transplantation. Previously, our lab developed a model of Non-human Primate (NHP) Brain death…2013 American Transplant Congress
Activated T Regulatory Cells Escape Death by Increasing Cytoplasmic Serine Protease Inhibitor 6 (SPI6)
Medicine, Harvard Medical School, Boston
Regulatory T cells (Tregs) can employ a granzyme B (GrB)-dependent mechanism to mediate suppression of effector cells by inducing their apoptosis. Herein, we show that…2013 American Transplant Congress
Low GFR after Kidney Donation Is Not Chronic Kidney Disease
Introduction:Living kidney donors have become of great importance to kidney transplantation. Obviously, living kidney donation is only justified if long-term donor safety is guaranteed. Many…2013 American Transplant Congress
Twice Daily Telaprevir in Combination with Peginterferon Alfa-2a/Ribavirin in HCV Genotype 1 Liver Transplant Recipients: Interim Pharmacokinetics of the REFRESH Study
Background: REFRESH is a 2-part Phase 2b, open-label clinical study assessing safety, efficacy, and pharmacokinetics (PK) of telaprevir (T) in combination with peginterferon alfa-2a (P)…
American Transplant Congress abstracts