2013 American Transplant Congress
Effect of Donor Comorbidites on Patient Survival – Standard Criteria Donor Kidney Compared to Expanded Criteria Donor Kidney Transplantation
The Transplant Institute, Henry Ford Hospital, Detroit, MI
Most studies of Expanded Criteria Donor (ECD) kidney (K) transplantation confirm that recipients(R) of ECD K have improved survival compared with matched dialysis-treated patients. However,…2013 American Transplant Congress
Predictors of Clostridium Difficile Infection in Liver Transplant Recipients: A 10 Year Single-Center Cohort Study
Transplant Institute, Henry Ford Hospital, Detroit, MI
Background: Clostridium difficile infection (CDI) is a common cause of morbidity and is associated with increased in-hospital mortality among solid organ transplant recipients. The incidence…2013 American Transplant Congress
Multicenter Banff Fibrosis Trial: Comparing Visual Assessment of Interstitial Fibrosis in Kidney Biopsies to Computer-Based Image Analysis and Organ Function, The
Interstitial fibrosis (IF) in renal biopsies is a valuable correlate for organ function, provides prognostic information and is a potential end point in trials.From 15…2013 American Transplant Congress
MicroRNA Profiling in Ischemia Reperfusion Injury Performed by Next Generation Sequencing in Human Renal Transplantation
Objectives: In a variety of (patho-) physiological situations microRNAs, small noncoding RNA fragments of 20-24 bp of length, display import post-transcriptional gene regulators. Current pathology…2013 American Transplant Congress
Targeting Inositol-Requiring Enzyme 1α in Prevention of Donor Specific Antibody (DSA) Mediated Rejection
Introduction: Inositol-requiring enzyme 1Α (IRE1Α), an endoplasmic reticulum-located transmembrane protein kinase, is the activator of transcription factor X-box-binding protein 1 (XBP1) that is required for…2013 American Transplant Congress
Different Effects of mTOR Inhibitor VS CN Inhibitor on Human B Cells Proliferations and Activation Markers
Background: Humoral immunity is increasingly recognized as an important factor in promoting transplant rejection. However, it is not well known how commonly used immunosuppressive drugs…2013 American Transplant Congress
Does Secondary Prophylaxis Prevent CMV Relapse Following Treatment of CMV Disease in Kidney Transplant Recipients?
Division of Infectious Diseases, Mount Sinai Hospital, New York, NY
BackgroundAlthough many centers use secondary prophylaxis to prevent relapse following the treatment of CMV disease in kidney transplant recipients (KTR), there is limited data to…2013 American Transplant Congress
Non-Renal Solid Organ Transplant (NRSOT): The Role of the Transplant Nephrologist before Advanced Stage Chronic Kidney Disease (CKD)
Background: Many patients who have not undergone appropriate kidney evaluation pre-NRSOT are found to have progressive or end-stage renal disease post-NRSOT. Recipients of NRSOT who…2013 American Transplant Congress
Decreased mTORC1 and Increased mTORC2 Activity Is Essential for Protective Differentiation Programs in Mesenchymal Stem Cells
mTOR translates microenvironmental signals into cell differentiation responses and controls cell fate including authophagy and apoptosis. Phenotypic conversion of mesenchymal stem cells (MSC) towards osteoblast…2013 American Transplant Congress
Cutaneous Collateral Axonal Sprouting Re-Innervates the Skin Component and Restores Sensation of Denervated Swine Osteomyocutaneous Allografts
BACKGROUND: Reconstructive transplantation is a viable treatment option for select patients with devastating tissue loss. However, sensorimotor recovery is critical determinant of its overall success.…
American Transplant Congress abstracts