2013 American Transplant Congress
Effect of Adipose Tissue Derived Mesenchymal Stem Cells on B Cells Proliferation and Differentiation, The
Background:Mesenchymal stem cells (MSC) have proven immunomodulatory capacity (in vitro and in vivo) which makes them a promising therapeutic tool in transplantation. However, research on…2013 American Transplant Congress
Alemtuzumab as Anti-Rejection Therapy in Kidney Transplant Patients Induces Homeostatic T Cell Proliferation and Impairs IL7 but Not IL2 Responses
Dept of Internal Medicine, ErasmusMC, University Medical Center, Rotterdam, Netherlands
Introduction: Induction therapy with alemtuzumab is known to result in T cell depletion followed by a slow immune recovery leading to hypo-responsiveness to the graft.…2013 American Transplant Congress
Clinical Application of Acoustic Radiation Force Impulse in Donor Kidney Compared with Biopsy Results: A Preliminary Report
Background: Donor kidney can have Interstitial fibrosis (IF) and tubular atrophy (TA), and it could be a source of poor graft function after transplantation. However,…2013 American Transplant Congress
Preservation of CMV-Specific Memory T Cell Responses with Belatacept
Emory Transplant Center, Emory University, Atlanta, GA
Belatacept has emerged with a paradoxical clinical picture including higher rejection rates and a potential signature of impaired viral immunity, particularly in viral-naÏve patients. We…2013 American Transplant Congress
Murine Transplantation of Beta Cell Lines Derived from Human Induced Pluripotent Stem Cells (iPSCs)
Surgery and Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA
In anticipation of cellular transplantation for diabetes, we sought to enrich and expand pancreatic beta-cell lines derived from iPSCs. iPCSs offer the advantage of "self"…2013 American Transplant Congress
Infectious Complications after Depleting or Non-Depleting Antibody Induction in Kidney Transplant Recipients over 60 Years of Age
The Methodist Hospital, Houston
Depleting antibodies have been associated with an increased infection risk after renal transplantation, particularly in older recipients. The purpose of this study is to examine…2013 American Transplant Congress
Alemtuzumab Induction and Belatacept-Based Immunosuppression in Renal Transplant Recipients: Peripheral Dynamics of T and B Cell Populations with Potential Regulatory Signatures
Emory Transplant Center, Emory University, Atlanta, GA
Belatacept has been approved as a calcineurin inhibitor (CNI) replacement, but its optimal use has not been determined. We have performed a pilot trial using…2013 American Transplant Congress
Matrix Metalloproteinase-12 Is a Novel Mediator of Hepatic Ischemia-Reperfusion Injury
Surgery, University of California, Los Angeles, CA
Hepatic ischemia reperfusion injury (IRI), linked to leukocyte recruitment and subsequent release of cytokines and free radicals, remains a significant problem in organ transplantation. Leukocyte…2013 American Transplant Congress
Nucleoside Reverse Transcriptase Inhibitors without HBIG Can Be Safely and Cost-Effectively Administered To Prevent Recurrent Hepatitis B Viremia Post-Liver Transplant
Division of Transplantation, New York University School of Medicine, New York, NY
Background: Hepatitis B virus (HBV)-related cirrhosis and malignancy are common indications for orthotopic liver transplantation (OLT) worldwide. Hepatitis B immunoglobulin (HBIG) infusions are widely used…2013 American Transplant Congress
Role of Mannose Binding Lectin on the Incidence of Rejection after Kidney and Other Solid Organ Transplantation
CHUV Transplantation Centre, Lausanne, Switzerland; CHUV Infectious Diseases, Lausanne, Switzerland
Background. The lectin pathway of complement activation and its major recognition molecule mannose binding lectin (MBL) may play an important role in immune damages after…
American Transplant Congress abstracts