ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Screening for West Nile Virus in California: Resolving IgM Anti-WNV in the Area With Dengue Seroprevalence

    C. Chinchilla-Reyes,1,2 D. Tanglao,1 T. Mone,3 M. Koss,1 M. Nowicki.1,2

    1Viracor-IBT Laboratories, Los Angeles; 2Mendez National Institute of Transplantation Foundation, Los Angeles; 3OneLegacy, Los Angeles.

    West Nile Virus (WNV) symptoms develop 2-15 days after exposure with a short period of viremia (6-7 days). It is possible to detect WNV in…
  • 2015 American Transplant Congress

    Dengue Virus Infection Among Renal Transplant Recipients: A Series of 10 Cases in a Tropical Country

    S. Costa,1,2 C. Jacinto,1 L. Martiniano,1 Y. Amaral,1 F. Paes,2 M. Sales,2 E. Daher,1,2 G. Junior,3 R. Esmeraldo.2

    1Post-Graduation Program in Medical Sciences, Department of Internal Medicine, School of Medicine, Federal University of Ceará, Fortaleza, Ceará, Brazil; 2Division of Renal Transplantation, Hospital Geral de Fortaleza, Fortaleza, Ceará, Brazil; 3Post-Graduation Program in Collective Health, School of Medicine, Sciences Center, University of Fortaleza, Fortaleza, Ceará, Brazil.

    Background: Dengue in an important endemic disease in many parts of the world. The aim of this study is to describe a case series of…
  • 2015 American Transplant Congress

    Incidence of Hepatitis B Virus Reactivation in Kidney Transplant Patients Who Received Rituximab Administration

    K. Omoto, M. Okumi, D. Toki, T. Shimizu, H. Ishida, K. Tanabe.

    Department of Urology, Tokyo Women's Medical University, Tokyo, Japan.

    OBJECTIVE:The efficacy of antiviral prophylaxis for rituximab (RIT)-associated hepatitis B virus (HBV) reactivation in patients with lymphoma has been recently reported. However, the immunological effect…
  • 2015 American Transplant Congress

    Changing Demographics of HIV+ Liver Transplant Candidates

    C. Durand, S. Gustafson, J. Locke, J. Snyder, B. Shelton, R. Reed, P. MacLennan, S. Mehta, A. Nellore, D. Segev.

    Johns Hopkins University, Baltimore, MD; Scientific Registry of Transplant Recipients (SRTR), Minneapolis Medical Research Foundation, Minneapolis, MN; University of Alabama, Birmingham, Birmingham, AL.

    Liver transplant (LT) is considered a reasonable therapeutic option for certain HIV+ patients with end-stage liver disease (ESLD). As OPTN does not collect HIV status…
  • 2015 American Transplant Congress

    Safety and Efficacy of Pegylated Interferon and Ribavirin for Chronic Hepatitis C Following Renal Transplantation

    G. Chen, L. Zhu, S. Chen, X. Wang, Z. Lin.

    Institute of Organ Transplantation, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei, China.

    Objective We sought to investigate the safety and efficacy of pegylated Interferon (PEG-IFN) and ribavirin for chronic hepatitis C (HCV) following renal transplantation.Methods Ten adult…
  • 2015 American Transplant Congress

    Increased Frequency of Terminally Differentiated and Exhausted CD8+ T Cells Is Associated With Adverse Clinical Outcome After Mechanical Circulatory Support Device Implantation

    J. Schaenman,1 Y. Korin,2 T. Sidwell,2 G. Sunga,2 G. Bondar,3 N. Wisniewski,3 M. Kwon,4 M. Cadeiras,3 M. Deng,3 E. Reed.2

    1Medicine/Infectious Diseases, David Geffen School of Medicine at UCLA, Los Angeles, CA; 2Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA; 3Medicine/Cardiology, David Geffen School of Medicine at UCLA, Los Angeles, CA; 4Cardiothoracic Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA.

    Clinical outcomes vary after mechanical circulatory support device (MCSD) implantation, with some patients developing multi organ system dysfunction (MOD), sometimes leading to death. We hypothesized…
  • 2015 American Transplant Congress

    A Cross-Organ Tissue Gene Expression Immune Signature Predates Chronicity

    Y. Ng, O. Bestard, T. Sigdel, S.-C. Hsieh, T. Tran, M. Sarwal.

    Transplantation Surgery, UC San Francisco, San Francisco, CA.

    Purpose Meta-analysis of 796 microarrays led to the discovery of 11 over-expressed genes (BASP1, CD6, CXCL9, CXCL10, INPP5D, ISG20, LCK, NKG7, PSMB9, RUNX3, and TAP1)…
  • 2015 American Transplant Congress

    Noninvasive Diagnostic and Predictive Value in Renal Transplant Recipients by Measurement of Urine BCA-1

    D. Chen, J. Chen, W. Peng.

    Kidney Disease Center, The First Affiliated Hospital, College of Medicine, Zhejiang University, Key Laboratory of Nephropathy, Zhejiang Province; Kidney Disease Immunology Laboratory, The Third Grade Laboratory, State Administration of Traditional Chinese.

    ObjectiveTo investigate the relationship between early-stage renal acute rejection and the level of BCA-1 in urine, explore the diagnostic value and noninvasive monitoring in early…
  • 2015 American Transplant Congress

    A Novel Humanized Mouse Model for the Study of Induced Pluripotent Stem Cell-Derived Tissue Transplantation Tolerance and Function

    M. Brown, I. Norman, Y. Zhou, J. Sullivan, W. Burlingham.

    Surgery/Transplant Division, University of Wisconsin-Madison, Madison, WI.

    Patient-specific induced pluripotent stem cells (iPSCs) hold great promise for regenerative medicine therapies, theoretically allowing for the creation of autologous replacement tissues devoid of many…
  • 2015 American Transplant Congress

    Chest Wall,Thymus, and Heart Transplant: Pushing the Boundary of Solid Organ Allotransplantation

    G. Torregrossa,1 M. Sosin,2 G. Gerosa,3 A. Dorafshar.2

    1Cardiothoracic Surgery, Mount Sinai Hospital, NYC, NY; 2Plastic and Reconstructive Surgery, Johns Hopkins Hospital, Baltimore, MD; 3Cardiac Surgery, Universita'di Padova, Padova, Italy.

    Objective:The last 10 years have ushered in the clinical reality of upper extremity and face transplantation with animal models and basic science evidence to support…
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