ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Current Status of US Intestinal and Multivisceral Transplantation: An Analysis of the UNOS Intestine Transplant Registry

    J. Cai,1 A. Qing,2 G. Wu,3 M. Everly,1 P. Terasaki.1

    1Terasaki Foundation Lab, Los Angeles, CA; 2Lincoln High School, Stockton, CA; 3The 4th Military Medical University, Xi-An, China.

    The purpose of this study is to analyze the current status of US intestinal transplantation (IT). As of 9/19/2014, 2441 IT have been performed in…
  • 2015 American Transplant Congress

    Chimerism for Early Detection of Graft Versus Host Disease in Intestinal Transplantation

    J. Garcia, T. Beduschi, P. Ruiz, A. Tekin, J. Fan, S. Nishida, G. Selvaggi, L. Cubley, R. Vianna.

    Miami Transplant Institute, University of Miami Miller School of Medicine, Miami, FL.

    Graft versus host disease (GVHD) is a potentially fatal complication after multivisceral transplantation (MVT). By definition, donor cells must be present in the blood of…
  • 2015 American Transplant Congress

    Everolimus With Low Dose Tacrolimus in Intestinal Transplantation

    T. Beduschi, J. Garcia, J. Lugo-Baruqui, J. Fan, S. Nishida, J. Jebrock, A. Tekin, G. Selvaggi, P. Ruiz, R. Vianna.

    Miami Transplant Institute, University of Miami Miller School of Medicine, Miami, FL.

    Introduction: Renal dysfunction is a well-known complication after organ transplant given immunosuppression (ISP) with calcineurin inhibitors. This is especially true after intestinal transplant (ITx) given…
  • 2015 American Transplant Congress

    Impact of Anti-CMV Prophylactic Therapy on the Development of CMV Quantiferon Sero-Conversion in High-Risk Patients

    A. Palanisamy, D. Taber, N. Pilch, C. Bratton, J. McGillicuddy, P. Baliga, K. Chavin.

    Transplant Surgery, Medical University of South Carolina, Charleston, SC.

    Body: Abdominal organ transplants at high risk for CMV infection (D+/R­) remain a difficult cohort to prevent late CMV infection despite prolonged valganciclovir (VGC) administration.…
  • 2015 American Transplant Congress

    Gene Expression Monitoring in Pediatric Heart Transplant Recipients

    C. Sutton,1 R. Butts,2 A. Burnette,3 A. Savage,2 W. Uber,1 A. Haney.1

    1Pharmacy, Medical University of South Carolina, Charleston, SC; 2Pediatric Cardiology, Medical University of South Carolina, Charleston, SC; 3Pediatric Heart Transplant, Medical University of South Carolina, Charleston, SC.

    Allomap® gene expression testing is a non-invasive screening tool approved for use in heart transplant recipients age 15 and older. Experience with Allomap® in pediatric…
  • 2015 American Transplant Congress

    Clinical Outcome of Patients With De Novo C1q Binding Donor-Specific HLA Antibodies After Renal Transplantation

    J. Bamoulid,1 A. Roodenburg,2 O. Staeck,1 C. Schoenemann,2 N. Lachmann,2 K. Budde.1

    1Nephrology, Charite Hospital-University of Medicine, Berlin, Germany; 2HLA Laboratory, Charite Hospital-University of Medicine, Berlin, Germany.

    A. Not all de novo donor-specific HLA antibodies (dnDSA) are causing immediate graft loss. The importance of complement-binding DSA was recently shown with a commercial…
  • 2015 American Transplant Congress

    DSA Monitoring in Kidney Transplant Recipients

    F. Pean,1 M. Cooper,1 J. Verbesey,1 A. Gilbert,1 B. Javaid,1 R. Mohammed,1 O. Timofeeva,2 J. Moore,1 K. Cruz,1 R. Ghasemian,1 T. Fishbein,1 M. Grafals.1

    1Medstar Georgetown Transplant Institute, Georgetown University, Washington, DC; 2Clinical Laboratory and Histocompatibility, Georgetown University, Washington, DC.

    Introduction: The development of DSA monitoring is a new technique to detect antibodies in kidney transplant recipients. Data has shown that development of DSA post…
  • 2015 American Transplant Congress

    Responsiveness to Rituximab, Plasmapheresis and Intravenous Immunoglobulins in Antibody Mediated Rejections After Kidney and Pancreas – Kidney Transplantation

    E. Minué,1 L. León,1 P. Uva,1 A. Dotta,1 J. Walther,1 O. Casanova,1 F. Togniolo,1 O. Guardia,1 M. Rial,1 E. Chuluyan,2 D. Casadei.1

    1Instituto de Nefrologia, Nephrology, Buenos Aires, Argentina; 2CEFYBO, Universidad de Buenos Aires-CONICET, Buenos Aires, Argentina.

    The antibody-mediated rejection (AMR) has become clinically critical because this form of rejection is usually unresponsive to conventional anti-rejection therapy. Therefore, it has been recognized…
  • 2015 American Transplant Congress

    Early Antibody Mediated Rejection in HLA Antibody Incompatible Kidney Transplantation – A Treatable Condition Without Heavy Induction Immunosuppression

    S. Daga,1,2 N. Krishnan,1 D. Lowe,3 F. Lam,1 C. Imray,1,2 H. Kashi,1 L. Tan,1 D. Briggs,3 R. Higgins.1,2

    1Renal Department, University Hospital, Coventry, United Kingdom; 2Warwick Medical School, University of Warwick, Coventry, United Kingdom; 3H&I Department, NHSBT, Birmingham, United Kingdom.

    Transplantation across preformed donor specific HLA antibodies (DSA) not only carries a risk of early acute antibody mediated rejection (AMR) and graft loss, but also…
  • 2015 American Transplant Congress

    Clinical and Immunologic Risk Factors Associated With Donor-Specific Antibody (DSA) Formation Following Renal Transplantation

    C. Johnson,1 S. Park,1 J. Schiller.2

    1Department of Surgery, Medical College of Wisconsin, Milwaukee, WI; 2Blood Center of Wisconsin, Milwaukee, WI.

    Background: De novo DSA formation is emerging as an important risk factor for adverse graft outcomes following renal transplantation. Specific pretransplant risk factors for DSA…
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