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American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Robotic Kidney Transplantation With Regional Hypothermia: Results from a Prospective Two-Arm Non-Randomized Controlled Trial (Ideal Phase 2b)

    R. Ahlawat,1 A. Sood,2 P. Ghosh,1 V. Kher,1 M. Bhandari,2 M. Menon.2

    1Institute of Kidney and Urology, Medanta, the Medicity, Gurgaon, Haryana, India; 2Vattikuti Urology Institute, Henry Ford Hospital, Detroit, MI.

    ObjectivesMinimally-invasive approaches to kidney transplantation are up-coming. We recently developed and described a novel technique of robotic KT (RKT) using intra corporeal graft cooling. Here,…
  • 2015 American Transplant Congress

    Hydrogen Sulfide Restores Protective Capacity of University of Wisconsin Solution During Normothermic Preservation

    J. Grewal,1 I. Lobb,1 M. Whiteman,3 A. Sener.1,2

    1Microbiology & Immunology, University of Western Ontario, London, ON, Canada; 2Matthew Mailing Centre for Translational Transplant Studies, London Health Sciences Centre, London, ON, Canada; 3Experimental Therapeutics, University of Exeter Medical School, Exeter, England, United Kingdom.

    Organ preservation solution is crucial in mitigating effects of ischemia reperfusion injury (IRI) associated with transplantation. Although University of Wisconsin (UW) solution is ideally suited…
  • 2015 American Transplant Congress

    Clinical and Radiological Predictors of Transplant Renal Artery Stenosis (TRAS)

    H. Wadei,1 D. Hodge,2 L. White,2 A. Ayub,3 N. Aslam,3 T. Gonwa,1 G. Frey,4 D. Sella,4 M. Mai.1

    1Transplant, Mayo Clinic, Jacksonville, FL; 2Biomedical Statistics, Mayo Clinic, Jacksonville, FL; 3Department of Medicine, Division of Nephrology and Hypertension, Mayo Clinic, Jacksonville, FL; 4Diagnostic Radiology, Mayo Clinic, Jacksonville, FL.

    Elevated peak systolic velocity (PSV) on Doppler ultrasound at the transplant renal artery (TRA) does not always correlate with true transplant renal artery stenosis (TRAS)…
  • 2015 American Transplant Congress

    Significant Association Between Foxp3 Gene Polymorphism and Outcomes in HBV-Related Liver Transplant Patients

    Y. Tanaka, V. Sapana, H. Ohdan.

    Gastroenterological and Transplant Surgery, Hiroshima University, Hiroshima, Japan.

    Background: Previous studies have demonstrated that CD4+Foxp3+ regulatory T (Treg) cells regulate HBV-related disease progression. The present study investigated the association between Treg cells and…
  • 2015 American Transplant Congress

    Safety and Efficacy of All Oral DAA Therapy for Genotype 1 HCV Post-Liver Transplant: Interval Results from the HCV-TARGET Multicenter Prospective Observational Study

    J. O'Leary,1 R. Brown,2 K. Reddy,3 A. Kuo,4 G. Morelli,5 R. Stravitz,6 G. Everson,7 C. Durand,8 H. Vargas,9 P. Kwo,10 C. Frenette,11 J. Peter,12 M. Vainorius,12 L. Akushevich,12 D. Nelson,5 M. Fried,12 N. Terrault.13

    1Baylor University Medical Center, TX; 2Columbia University, NY; 3University of Pennsylvania, PA; 4UCSD, CA; 5University of Florida, Gainesville, Gainesville, FL; 6Virginia Commonwealth University, VA; 7University of Colorado, CO; 8Johns Hopkins, MD; 9Mayo Clinic, AZ; 10Indiana University, IL; 11Scipps Clinic, CA; 12University of North Carolina, NC; 13UCSF, CA.

    The safety and efficacy of direct-acting antivirals (DAA) for HCV post-LT remain unknown. METHODS: We describe the safety and efficacy of all oral DAA-therapy for…
  • 2015 American Transplant Congress

    Changes in Utilization, Discard, and Outcomes Associated With Hepatitis C (+) Donor Livers in the Era of Direct Acting Anti-Retroviral Therapy

    M. Bowring, L. Kucirka, X. Luo, A. Massie, D. Segev, C. Durand.

    Johns Hopkins University, Baltimore, MD.

    While 45% of liver candidates are hepatitis C (HCV) (+) and might benefit from an HCV (+) donor liver, only 7.1% receive one, and HCV…
  • 2015 American Transplant Congress

    The Impact of the New Antivirals Sofosfuvir/Ledipasvir on Liver Transplantation for Hepatitis C Cirrhosis

    S. Munoz,1 D. Reich,2 K. Rothstein.1

    1Div of Hepatology, Liver Failure Unit, Hanemann University Hospital, Philadelphia, PA; 2Liver, Kidney and Pancreas Transplant Program, Hahnemann University Hospital, Philadelphia, PA.

    The approval of potent antiviral therapy (AVT) with sofosfuvir/ledipasvir (sof/ldv) for hepatitis C (HCV) dramatically increased cure rates (SVR) to nearly 100%. A recent prospective…
  • 2015 American Transplant Congress

    Outcomes of HIV+ Liver Transplant Recipients Compared to HCV+ or HIV+/HCV+ Co-Infected Recipients: The “Real World” Experience

    D. Sawinski,1 G. David,2 E. Blumberg,3 P. Abt,4 R. Bloom,1 K. Forde.2

    1Renal Division, Univ. of Penn, Philadelphia, PA; 2Gastroenterology Division, Univ. of Penn, Philadelphia, PA; 3Infectious Disease, Univ. of Penn, Philadelphia, PA; 4Surgery, Univ of Penn, Philadelphia, PA.

    End stage liver disease is a frequent cause of mortality in patients with HIV. Though demonstrated in the NIH observational trial, the effectiveness of LT…
  • 2015 American Transplant Congress

    Post-Liver Transplant Metabolic Syndrome Increases the Risk of Recurrent Fibrosis in Patients With Hepatitis C

    R. Sharma, M. Laurito, R. Brown, Jr., E. Verna.

    Department of Medicine, Columbia University, New York, NY.

    Introduction: Post-liver transplant (LT) metabolic syndrome (MS) is common and may impact fibrosis progression in LT recipients with hepatitis C virus (HCV). Methods: All adults…
  • 2015 American Transplant Congress

    Validation of the Model for End-Stage Liver Disease Score Criteria in Liver Transplantation for Acute Flare Up of Hepatitis B in Non-Cirrhotic Liver

    W.-C. Lee,1 T.-J. Wu,1 C.-F. Lee,1 R.-S. Soong,1 C.-H. Cheng,1 H.-S. Chou,1 T.-H. Wu,1 K.-M. Chan,1 Y.-C. Wang,1 C.-S. Lee.2

    1Liver and Transplantation Surgery, Chang-Gung Memorial Hospital, Chang-Gung University College of Medicine, Taoyuan, Taiwan; 2Hepatology, Chang-Gung Memorial Hospital, Chang-Gung University College of Medicine, Taoyuan, Taiwan.

    Background: Decision of necessity of urgent liver transplantation for acute flare up of hepatitis B in the patients without cirrhosis is difficult. The MELD score…
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