ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Angiotensin II Blockade and Fibroblast Growth Factor-23 in Stable Kidney Transplant Recipients.

    O. Sanchez, S. Reule, S. Li, D. Berglund, R. Spong, H. Ibrahim.

    U of MN, Mpls.

    Introduction: FGF-23 has been linked to allograft failure. However, careful serial profiling of FGF-23 has not been done. Therefore, we measured FGF-23 levels in recipients…
  • 2016 American Transplant Congress

    Urgent Kidney Transplantation as Successful Treatment of Calciphylaxis in Three Patients with End-Stage Kidney Failure.

    E. Nordheim,1 D. Dahle,1 I. Syse,1 A. Åsberg,1,2 A. Reisæter,1 H. Holdaas,1 T. Jenssen,1,3 A. Hartmann.1,4

    1Transplantation Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway; 2Shool of Pharmacy, University of Oslo, Oslo, Norway; 3Kidney, Arctic University of Tromsø, Tromsø, Norway; 4Institute of Clinical Medicine, Medical Faculty, University of Oslo, Oslo, Norway.

    Background: Calciphylaxis often referred to as calcific uremic arteriolopathy (CUA) is a rare and serious complication with limited treatment options. Kidney transplantation restores kidney function…
  • 2016 American Transplant Congress

    Post-Transplantation Hypomagnesemia as a Predictor of Survival Among the Kidney Transplant Population.

    T. Hod, B. Patibandla, A. Chandraker.

    Transplant Research Center, Brigham and women's hospital, Boston, MA.

    We have previously shown a robust relationship between low magnesium in the first year post-transplant and better long-term kidney allograft function. Given this somewhat counterintuitive…
  • 2016 American Transplant Congress

    The Burden and Outcomes of Fractures in Kidney Transplant Recipients.

    N. Atagu, T. Nguyen, N. Phan, O. Famure, Y. Li, J. Kim.

    Multi-Organ Transplant Program, Toronto General Hospital, University Health Network, Toronto, ON, Canada.

    Background: Kidney transplantation confers an increased risk for bone fractures. However, there is poor consensus on the incidence of fractures in kidney transplant recipients (KTRs),…
  • 2016 American Transplant Congress

    Significant Association of Innate Immune Related Genes Polymorphism on Infectious Complications Following Early Post Renal Transplantation phase.

    L. Das, K. Ide, Y. Tanaka, S. Shimizu, N. Tanimine, S. Verma, H. Ohdan.

    Department of Gastroenrological and Transplant Surgery, Hiroshima University, Hiroshima, Japan.

    ObjectiveInfectious complication is the leading cause of graft dysfunction and patient loss after renal transplantation (RT). In the early post-transplant phase where acquired immunity is…
  • 2016 American Transplant Congress

    Association of Genetic Polymorphisms of Angiopoietin-Like 4 with Proteinuria in Kidney Allograft Recipients.

    Y. Chang,1,4 T. Shah,2,4 Y.-T. Chuang,3 D. Min.4

    1Mendez National Institute of Transplantation Foundation, Los Angeles, CA; 2St. Vincent Medical Center, Los Angeles, CA; 3Taipei medical university, Taipei, Taiwan; 4Western University of Health Sciences, Pomona.

    Background: Proteinuria is a hallmark of glomerular injury, and persistent proteinuria is associated with graft failure in kidney transplant patients. Recently, it is known that…
  • 2016 American Transplant Congress

    Marked Alterations in Gene Expression in Peripheral Blood Leukocytes of Kidney Transplant (tx) Recipients Following Mycophenolic Acid (MPA) Treatment.

    K. Sanghavi,1 B. Wu,1 C. Dorr,2 A. Muthuswamy,2 W. Guan,1 D. Schladt,2 R. Remmel,1 D. Ilke,3 A. Matas,1 A. Israni,2 W. Oetting,1 P. Jacobson.1

    1University of Minnestoa, Minneapolis; 2MMRC, Hennepin County Medical Center, Minneapolis; 3Rho.

    MPA exerts its immunosuppressive activity by inhibiting IMPDH2 enzyme, halting DNA synthesis in T and B lymphocytes. Cell culture models have shown MPA effects on…
  • 2016 American Transplant Congress

    What if Mycophenolic Acid Product Is Discontinued Less Than 6 Weeks Before Pregnancy?

    N. Sifontis,1 L. Coscia,2 D. Armenti,2 S. Constantinescu,2,3 M. Moritz.2,4

    1Pharmacy Practice, Temple University, Philadelphia, PA; 2Gift of Life Institute, National Transplantation Pregnancy Registry (NTPR), Philadelphia, PA; 3Medicine, Temple University, Philadelphia, PA; 4Surgery, Lehigh Valley Health Network, Allentown, PA.

    It is recommended that mycophenolic acid (MPA) products be discontinued at least 6 wks prior to conceiving due to potential teratogenic effects and increase risk…
  • 2016 American Transplant Congress

    Pregnancy in the Renal Transplant Recipient: Pregnancy Viability and Effects on Graft Function.

    A. Lima, M. Cristelli, C. Teixeira, I. Pietrobom, G. Basso, L. Viana, M. de Paula, C. C[acirc]ndido, H. Tedesco-Silva, J. Pestana.

    Nephrology, Hospital do Rim, São Paulo, Brazil.

    Background: Fertility in women is recovered few months after kidney transplantation. However, pregnancy viability and maternal complications remain uncertain. Methods: We studied data of patients…
  • 2016 American Transplant Congress

    Clinical Significance of Mycophenolic Acid Therapeutic Drug Monitoring in Kidney Transplant Recipients.

    C.-D. Kim, J.-H. Cho, K. Kim, M. Kim, W. Do, Y. Yang, T. Yim, I. Hwang, J.-H. Lee, H.-Y. Jung, J.-Y. Choi, S.-H. Park, Y.-L. Kim.

    Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea.

    Background: Mycophenolic acid (MPA) is a widely used immunosuppressant to prevent acute rejection in kidney transplant recipients (KTRs). However, clinical significance of MPA therapeutic drug…
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